TLR7 (NM_016562) Human 3' UTR Clone

CAT#: SC216098

3`UTR clone of toll-like receptor 7 (TLR7) for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: TLR7
• Synonyms: TLR7-like
• ACCN: NM_016562
• Insert Size: 1718
• Sequence Data:
  Insert Sequence

  >SC216098 3'UTR clone of NM_016562
  The sequence shown below is from the reference sequence of NM_016562. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  CAGGTGTTCAAGGAAACGGTCTAGCCCTTCTTTGCAAAACACAACTGCCTAGTTTACCAAGGAGAGGCCT
  GGCTGTTTAAATTGTTTTCATATATATCACACCAAAAGCGTGTTTTGAAATTCTTCAAGAAATGAGATTG
  CCCATATTTCAGGGGAGCCACCAACGTCTGTCACAGGAGTTGGAAAGATGGGGTTTATATAATGCATCAA
  GTCTTCTTTCTTATCTCTCTGTGTCTCTATTTGCACTTGAGTCTCTCACCTCAGCTCCTGTAAAAGAGTG
  GCAAGTAAAAAACATGGGGCTCTGATTCTCCTGTAATTGTGATAATTAAATATACACACAATCATGACAT
  TGAGAAGAACTGCATTTCTACCCTTAAAAAGTACTGGTATATACAGAAATAGGGTTAAAAAAAACTCAAG
  CTCTCTCTATATGAGACCAAAATGTACTAGAGTTAGTTTAGTGAAATAAAAAACCAGTCAGCTGGCCGGG
  CATGGTGGCTCATGCTTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCACGAGGTCAGGAGTT
  TGAGACCAGTCTGGCCAACATGGTGAAACCCCGTCTGTACTAAAAATACAAAAATTAGCTGGGCGTGGTG
  GTGGGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAGGTGGAGG
  TGGCAGTGAGCCGAGATCACGCCACTGCAATGCAGCCCGGGCAACAGAGCTAGACTGTCTCAAAAGAACA
  AAAAAAAAAAAACACAAAAAAACTCAGTCAGCTTCTTAACCAATTGCTTCCGTGTCATCCAGGGCCCCAT
  TCTGTGCAGATTGAGTGTGGGCACCACACAGGTGGTTGCTGCTTCAGTGCTTCCTGCTCTTTTTCCTTGG
  GCCTGCTTCTGGGTTCCATAGGGAAACAGTAAGAAAGAAAGACACATCCTTACCATAAATGCATATGGTC
  CACCTACAAATAGAAAAATATTTAAATGATCTGCCTTTATACAAAGTGATATTCTCTACCTTTGATAATT
  TACCTGCTTAAATGTTTTTATCTGCACTGCAAAGTACTGTATCCAAAGTAAAATTTCCTCATCCAATATC
  TTTCAAACTGTTTTGTTAACTAATGCCATATATTTGTAAGTATCTGCACACTTGATACAGCAACGTTAGA
  TGGTTTTGATGGTAAACCCTAAAGGAGGACTCCAAGAGTGTGTATTTATTTATAGTTTTATCAGAGATGA
  CAATTATTTGAATGCCAATTATATGGATTCCTTTCATTTTTTGCTGGAGGATGGGAGAAGAAACCAAAGT
  TTATAGACCTTCACATTGAGAAAGCTTCAGTTTTGAACTTCAGCTATCAGATTCAAAAACAACAGAAAGA
  ACCAAGACATTCTTAAGATGCCTGTACTTTCAGCTGGGTATAAATTCATGAGTTCAAAGATTGAAACCTG
  ACCAATTTGCTTTATTTCATGGAAGAAGTGATCTACAAAGGTGTTTGTGCCATTTGGAAAACAGCGTGCA
  TGTGTTCAAGCCTTAGATTGGCGATGTCGTATTTTCCTCACGTGTGGCAATGCCAAAGGCTTTACTTTAC
  CTGTGAGTACACACTATATGAATTATTTCCAACGTACATTTAATCAATAAGGGTCACAAATTCCCAAATC
  AATCTCTGGAATAAATAGAGAGGTAATTAAATTGCTGG
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_016562.3
• Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X. [provided by RefSeq, Jul 2008]
• Locus ID: 51284