KDELR2 (NM_001100603) Human 3' UTR Clone
CAT#: SC216938
3`UTR clone of KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 (KDELR2) transcript variant 2 for miRNA target validation
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Specifications
Product Data | |
Vector | pMirTarget |
Species | Human |
Transfection Reporter | RFP |
Assay Reporter | Luciferase |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Symbol | KDELR2 |
Synonyms | ELP-1; ERD2.2 |
ACCN | NM_001100603 |
Insert Size | 1907 |
Sequence Data |
>SC216938 3'UTR clone of NM_001100603
The sequence shown below is from the reference sequence of NM_001100603. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon CAATTGGCAGAGCTCAGAATTCAAGCGATCGC AAACGCAGAGGAAAAGAGCCAGAAGGTTTCTGTTTAATGCATCTTGCCTTATCTTTTTTTATTACTGTGT ACAAAGATTTTTTTACACAAAGAAACTTAATGCTGTATTAATAAATTCAGTGTGTAGCTTCAATTGGGAT AGTTCCAAAAGTGAAGATTTTGTGAGGAATAAGTGCAAATTTTTTTTTTATTTTAAAAAATTCTTTGAAA CTCTTAAGTCTTTGTGTCTGCAATGAAATTGTACTCCTTGACAGTTGATAGATTATATATTCTTCCATCC CTCAAACTTGCATTCCACTATATTTATTTTTTGGCAAAAGATGAGCTGTATTTGTTTGAAATCTGAGACA CTATGTTCAATTGGATGTATCTGTTCAAATTTATTCCCACGTGACGTGGAAGTCCTTCGTTGGATGTCAC AACACTACATTTAAGGTTGGTAAGGATGACTTGGAGGTCCATGGTTTTCATTACCAACATTTTAAGATTC TGAATGTCGATGGAGTCTCACTGAAGAGTCACCAAAGGTGCCTGCCCTCCTCCCCTGCTGGGAAGTGTCA GTTGGAGACTGTCCCAAGGGTGCTGAAGAATCCAGTGGCAGGGGTTCTGGCTGCTTTCCATCTGAGTGTG GGATGGGAGGGGTGTTCATGATCATTTGGATATAGCAATCTACTCTGAGAAATGGAACACAAGGAGTTAC CTATCACTTTCACTTATAATTCCAAAAGATGACTACAACCATGTCCATGCTCAGATTCAAACAGTTTTCC ATATCACTTTTGGGTGGTAAGATGATTTAATTACAGTTTTTTTTTTAATTGGCAGCACCACTAACCATTC CTTACATTCTTTTTTGTATGTGTGGTTTTCTTTTTATTTAACCCGCAGCCGACATCGTAGTTTCTTGTTT TGTTTTGTTTTACAGAGCTGTTGCATGACTTATGTTACCATCCTAAAAAACACTATATTAAACATGGAAT AAATTGTCTTTTTATGAATTAGGCTTTTTGAACATCCTGTGTTGGGATTTTTTTGTTTTTCAATTGGCAA CAAAAGCTCTGTAGGGCTGCAGACATTTAAAGTTCACATAATCATCTGTAAGACATTATGTATTTTGTGG AAATACTAGAATTTTTTTCCTGATTTTGCCATTATATGGATTTGCTATTTTTTGATTAATGCAAAAGTAT ATGACTTTGTTTTTTATGTGATACACCATAAATATTAAAGTGTTGAATACTAACAGTGCTGACTACAAGA AGGATGTAGTATTTTGGCTTTCTGCATTACAACGTCTTCTGGAGGAAGGGAGCAGGATGGGTTTCATTTG TATCTAGTGTGTGTCTTAACATCTTTCTAAATCGGCAGTGTAACTGCATAGTTTAACTTCCTGTCTGTCT CCCTCATTTTACTCTTCCCTCCTTGTCTTATGTTTTGGCTTTTGTGTATCAGAGCATCTTTCTTTGCAGC ATCCTAGTCTTGCTTCAGTTTCTGTGGTCTCTTTTCATCCTGCTTGAAGATTCGGAGTGTGGAAGGAGGC TAGGAAGTCTGGTGCAGTAGGTGAGCAGACCTCTTGCTGCCCAGCCCAGGGTGGGTGGGGCGCACACCTG TCTTTGTGCATGCAAATCTGATACACCTGGCGCATCCTCTGGAGAGCACAACGCATGGAAAGGTCTGGAA GCTCTGTGTAGCCATTCCTTCTGCAGTCATCCTACCCAAGTAAAAGTAACCTTGGCTATGTTACCACCGT TTTGGTCACCCAGGAGGACATCTTAGCAAGGGTGCCTGCGAGGGAGTGTGGGACTGGGCCTCATCCTCGC CGGCGTTGGAAACCAAGGCCTTGTATGCCACGCCTTATGAAGCACTGTTTCACAGTTACTTTCACTTCCC GAATAAAGGTTACCAGG ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_001100603.1 |
Summary | Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. KDELR2 was the second member of the family to be identified, and it encodes a protein which is 83% identical to the KDELR1 gene product. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] |
Locus ID | 11014 |
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