KDELR2 (NM_001100603) Human 3' UTR Clone

CAT#: SC216938

3`UTR clone of KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 (KDELR2) transcript variant 2 for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: KDELR2
• Synonyms: ELP-1; ERD2.2
• ACCN: NM_001100603
• Insert Size: 1907
• Sequence Data:
  Insert Sequence

  >SC216938 3'UTR clone of NM_001100603
  The sequence shown below is from the reference sequence of NM_001100603. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  AAACGCAGAGGAAAAGAGCCAGAAGGTTTCTGTTTAATGCATCTTGCCTTATCTTTTTTTATTACTGTGT
  ACAAAGATTTTTTTACACAAAGAAACTTAATGCTGTATTAATAAATTCAGTGTGTAGCTTCAATTGGGAT
  AGTTCCAAAAGTGAAGATTTTGTGAGGAATAAGTGCAAATTTTTTTTTTATTTTAAAAAATTCTTTGAAA
  CTCTTAAGTCTTTGTGTCTGCAATGAAATTGTACTCCTTGACAGTTGATAGATTATATATTCTTCCATCC
  CTCAAACTTGCATTCCACTATATTTATTTTTTGGCAAAAGATGAGCTGTATTTGTTTGAAATCTGAGACA
  CTATGTTCAATTGGATGTATCTGTTCAAATTTATTCCCACGTGACGTGGAAGTCCTTCGTTGGATGTCAC
  AACACTACATTTAAGGTTGGTAAGGATGACTTGGAGGTCCATGGTTTTCATTACCAACATTTTAAGATTC
  TGAATGTCGATGGAGTCTCACTGAAGAGTCACCAAAGGTGCCTGCCCTCCTCCCCTGCTGGGAAGTGTCA
  GTTGGAGACTGTCCCAAGGGTGCTGAAGAATCCAGTGGCAGGGGTTCTGGCTGCTTTCCATCTGAGTGTG
  GGATGGGAGGGGTGTTCATGATCATTTGGATATAGCAATCTACTCTGAGAAATGGAACACAAGGAGTTAC
  CTATCACTTTCACTTATAATTCCAAAAGATGACTACAACCATGTCCATGCTCAGATTCAAACAGTTTTCC
  ATATCACTTTTGGGTGGTAAGATGATTTAATTACAGTTTTTTTTTTAATTGGCAGCACCACTAACCATTC
  CTTACATTCTTTTTTGTATGTGTGGTTTTCTTTTTATTTAACCCGCAGCCGACATCGTAGTTTCTTGTTT
  TGTTTTGTTTTACAGAGCTGTTGCATGACTTATGTTACCATCCTAAAAAACACTATATTAAACATGGAAT
  AAATTGTCTTTTTATGAATTAGGCTTTTTGAACATCCTGTGTTGGGATTTTTTTGTTTTTCAATTGGCAA
  CAAAAGCTCTGTAGGGCTGCAGACATTTAAAGTTCACATAATCATCTGTAAGACATTATGTATTTTGTGG
  AAATACTAGAATTTTTTTCCTGATTTTGCCATTATATGGATTTGCTATTTTTTGATTAATGCAAAAGTAT
  ATGACTTTGTTTTTTATGTGATACACCATAAATATTAAAGTGTTGAATACTAACAGTGCTGACTACAAGA
  AGGATGTAGTATTTTGGCTTTCTGCATTACAACGTCTTCTGGAGGAAGGGAGCAGGATGGGTTTCATTTG
  TATCTAGTGTGTGTCTTAACATCTTTCTAAATCGGCAGTGTAACTGCATAGTTTAACTTCCTGTCTGTCT
  CCCTCATTTTACTCTTCCCTCCTTGTCTTATGTTTTGGCTTTTGTGTATCAGAGCATCTTTCTTTGCAGC
  ATCCTAGTCTTGCTTCAGTTTCTGTGGTCTCTTTTCATCCTGCTTGAAGATTCGGAGTGTGGAAGGAGGC
  TAGGAAGTCTGGTGCAGTAGGTGAGCAGACCTCTTGCTGCCCAGCCCAGGGTGGGTGGGGCGCACACCTG
  TCTTTGTGCATGCAAATCTGATACACCTGGCGCATCCTCTGGAGAGCACAACGCATGGAAAGGTCTGGAA
  GCTCTGTGTAGCCATTCCTTCTGCAGTCATCCTACCCAAGTAAAAGTAACCTTGGCTATGTTACCACCGT
  TTTGGTCACCCAGGAGGACATCTTAGCAAGGGTGCCTGCGAGGGAGTGTGGGACTGGGCCTCATCCTCGC
  CGGCGTTGGAAACCAAGGCCTTGTATGCCACGCCTTATGAAGCACTGTTTCACAGTTACTTTCACTTCCC
  GAATAAAGGTTACCAGG
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_001100603.1
• Summary: Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. KDELR2 was the second member of the family to be identified, and it encodes a protein which is 83% identical to the KDELR1 gene product. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
• Locus ID: 11014