Caveolin 1 (CAV1) (NM_001753) Human 3' UTR Clone

CAT#: SC216973

3`UTR clone of caveolin 1 caveolae protein 22kDa (CAV1) for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: CAV1
• Synonyms: BSCL3; CGL3; LCCNS; MSTP085; PPH3; VIP21
• ACCN: NM_001753
• Insert Size: 1910 bp
• Sequence Data:
  Insert Sequence

  >SC216973 3'UTR clone of NM_001753
  The sequence shown below is from the reference sequence of NM_001753. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  CAGCAATGTCCGCATCAACTTGCAGAAAGAAATATAAATGACATTTCAAGGATAGAAGTATACCTGATTT
  TTTTTCCTTTTAATTTTCCTGGTGCCAATTTCAAGTTCCAAGTTGCTAATACAGCAACAATTTATGAATT
  GAATTATCTTGGTTGAAAATAAAAAGATCACTTTCTCAGTTTTCATAAGTATTATGTCTCTTCTGAGCTA
  TTTCATCTATTTTTGGCAGTCTGAATTTTTAAAACCCATTTAAATTTTTTTCCTTACCTTTTTATTTGCA
  TGTGGATCAACCATCGCTTTATTGGCTGAGATATGAACATATTGTTGAAAGGTAATTTGAGAGAAATATG
  AAGAACTGAGGAGGAAAAAAAAAAAAAAGAAAAGAACCAACAACCTCAACTGCCTACTCCAAAATGTTGG
  TCATTTTATGTTAAGGGAAGAATTCCAGGGTATGGCCATGGAGTGTACAAGTATGTGGGCAGATTTTCAG
  CAAACTCTTTTCCCACTGTTTAAGGAGTTAGTGGATTACTGCCATTCACTTCATAATCCAGTAGGATCCA
  GTGATCCTTACAAGTTAGAAAACATAATCTTCTGCCTTCTCATGATCCAACTAATGCCTTACTCTTCTTG
  AAATTTTAACCTATGATATTTTCTGTGCCTGAATATTTGTTATGTAGATAACAAGACCTCAGTGCCTTCC
  TGTTTTTCACATTTTCCTTTTCAAATAGGGTCTAACTCAGCAACTCGCTTTAGGTCAGCAGCCTCCCTGA
  AGACCAAAATTAGAATATCCATGACCTAGTTTTCCATGCGTGTTTCTGACTCTGAGCTACAGAGTCTGGT
  GAAGCTCACTTCTGGGCTTCATCTGGCAACATCTTTATCCGTAGTGGGTATGGTTGACACTAGCCCAATG
  AAATGAATTAAAGTGGACCAATAGGGCTGAGCTCTCTGTGGGCTGGCAGTCCTGGAAGCCAGCTTTCCCT
  GCCTCTCATCAACTGAATGAGGTCAGCATGTCTATTCAGCTTCGTTTATTTTCAAGAATAATCACGCTTT
  CCTGAATCCAAACTAATCCATCACCGGGGTGGTTTAGTGGCTCAACATTGTGTTCCCATTTCAGCTGATC
  AGTGGGCCTCCAAGGAGGGGCTGTAAAATGGAGGCCATTGTGTGAGCCTATCAGAGTTGCTGCAAACCTG
  ACCCCTGCTCAGTAAAGCACTTGCAACCGTCTGTTATGCTGTGACACATGGCCCCTCCCCCTGCCAGGAG
  CTTTGGACCTAATCCAAGCATCCCTTTGCCCAGAAAGAAGATGGGGGAGGAGGCAGTAATAAAAAGATTG
  AAGTATTTTGCTGGAATAAGTTCAAATTCTTCTGAACTCAAACTGAGGAATTTCACCTGTAAACCTGAGT
  CGTACAGAAAGCTGCCTGGTATATCCAAAAGCTTTTTATTCCTCCTGCTCATATTGTGATTCTGCCTTTG
  GGGACTTTTCTTAAACCTTCAGTTATGATTTTTTTTTCATACACTTATTGGAACTCTGCTTGATTTTTGC
  CTCTTCCAGTCTTCCTGACACTTTAATTACCAACCTGTTACCTACTTTGACTTTTTGCATTTAAAACAGA
  CACTGGCATGGATATAGTTTTACTTTTAAACTGTGTACATAACTGAAAATGTGCTATACTGCATACTTTT
  TAAATGTAAAGATATTTTTATCTTTATATGAAGAAAATCACTTAGGAAATGGCTTTGTGATTCAATCTGT
  AAACTGTGTATTCCAAGACATGTCTGTTCTACATAGATGCTTAGTCCCTCATGCAAATCAATTACTGGTC
  CAAAAGATTGCTGAAATTTTATATGCTTACTGATATATTTTACAATTTTTTATCATGCATGTCCTGTAAA
  GGTTACAAGCCTGCACAATA
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.

Reference Data

• RefSeq: NM_001753.4
• Summary: 'The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.[provided by RefSeq, Mar 2010]'
• Locus ID: 857