Klotho (KL) (NM_004795) Human 3' UTR Clone

CAT#: SC217236

3`UTR clone of klotho (KL) for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: KL
• Synonyms: klotho; OTTHUMP00000018796
• ACCN: NM_004795
• Insert Size: 1978
• Sequence Data:
  Insert Sequence

  >SC217236 3'UTR clone of NM_004795
  The sequence shown below is from the reference sequence of NM_004795. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  ACTACTCGAAGAAAGGCAGAAGAAGTTACAAATAGTTCTGAACATTTTTCTATTCATTCATTTTGAAATA
  ATTATGCAGACACATCAGCTGTTAACCATTTGCACCTCTAAGTGTTGTGAAACTGTAAATTTCATACATT
  TGACTTCTAGAAAACATTTTTGTGGCTTATGACAGAGGTTTTGAAATGGGCATAGGTGATCGTAAAATAT
  TGAATAATGCGAATAGTGCCTGAATTTGTTCTCTTTTTGGGTGATTAAAAAACTGACAGGCACTATAATT
  TCTGTAACACACTAACAAAAGCATGAAAAATAGGAACCACACCAATGCAACATTTGTGCAGAAATTTGAA
  TGACAAGATTAGGAATATTTTCTTCTGCACCCACTTCTAAATTTAATGTTTTTCTGGAAGTAGTAATTGC
  AAGAGTTCGAATAGAAAGTTATGTACCAAGTAACCATTTCTCAGCTGCCATAATAATGCCTAGTGGCTTC
  CCCTCTGTCAAATCTAGTTTCCTATGGAAAAGAAGATGGCAGATACAGGAGAGACGACAGAGGGTCCTAG
  GCTGGAATGTTCCTTTCGAAAGCAATGCTTCTATCAAATACTAGTATTAATTTATGTATCTGGTTAATGA
  CATACTTGGAGAGCAAATTATGGAAATGTGTATTTTATATGATTTTTGAGGTCCTGTCTAAACCCTGTGT
  CCCTGAGGGATCTGTCTCACTGGCATCTTGTTGAGGGCCTTGCACATAGGAAACTTTTGATAAGTATCTG
  CGGAAAAACAAACATGAATCCTGTGATATTGGGCTCTTCAGGAAGCATAAAGCAATTGTGAAATACAGTA
  TACCGCAGTGGCTCTAGGTGGAGGAAAGGAGGAAAAAGTGCTTATTATGTGCAACATTATGATTAATCTG
  ATTATACACCATTTTTGAGCAGATCTTGGAATGAATGACATGACCTTTCCCTAGAGAATAAGGATGAAAT
  AATCACTCATTCTATGAACAGTGACACTACTTTCTATTCTTTAGCTGTACTGTAATTTCTTTGAGTTGAT
  AGTTTTACAAATTCTTAATAGGTTCAAAAGCAATCTGGTCTGAATAACACTGGATTTGTTTCTGTGATCT
  CTGAGGTCTATTTTATGTTTTTGCTGCTACTTCTGTGGAAGTAGCTTTGAACTAGTTTTACTTTGAACTT
  TCACGCTGAAACATGCTAGTGATATCTAGAAAGGGCTAATTAGGTCTCATCCTTTAATGCCCCTTAAATA
  AGTCTTGCTGATTTTCAGACAGGGAAGTCTCTCTATTACACTGGAGCTGTTTTATAGATAAGTCAATATT
  GTATCAGGCAAGATAAACCAATGTCATAACAGGCATTGCCAACCTCACTGACACAGGGTCATAGTGTATA
  ATAATATACTGTACTATATAATATATCATCTTTAGAGGTATGATTTTTTCATGAAAGATAAGCTTTTGGT
  AATATTCATTTTAAAGTGGACTTATTAAAATTGGATGCTAGAGAATCAAGTTTATTTTATGTATATATTT
  TTCTGATTATAAGAGTAATATATGTTCATTGTAAAAATTTTTAAAACACAGAAACTATATGCAAAGAAAA
  AATAAAAATTATCTATAATCTCAGAACCCAGAAATAGCCACTATTAACATTTCCTACGTATTTTATTTTA
  CATAGATCATATTGTATATAGTTAGTATCTTTATTAATTTTTATTATGAAACTTTCCTTTGTCATTATTA
  GTCTTCAAAAGCATGATTTTTAATAGTTGTTGAGTATTCCACCACAGGAATGTATCACAACTTAACCGTT
  CCCGTTTGTTAGACTAGTTTCTTATTAATGTTGATGAATGTTGTTTAAAAATAATTTTGTTGCTACATTT
  ACTTTAATTTCCTTGACTGTAAAGAGAAGTAATTTTGCTCCTTGATAAAGTATTATATTAATAATAAATC
  TGCCTGCAACTTTTTGCC
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_004795.3
• Summary: This gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss. [provided by RefSeq, Jul 2008]
• Locus ID: 9365