CLDN19 (NM_148960) Human 3' UTR Clone

CAT#: SC217319

3`UTR clone of claudin 19 (CLDN19) transcript variant 1 for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: CLDN19
• Synonyms: HOMG5
• ACCN: NM_148960
• Insert Size: 2040
• Sequence Data:
  Insert Sequence

  >SC217319 3'UTR clone of NM_148960
  The sequence shown below is from the reference sequence of NM_148960. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  CAGTTGTTAAATTGCCCGCCTCCGCCAAGGGCCCCCTGGGTGTGTAATGTCCAGTCCCCAGCCAGGCTCT
  GTCCCCTGCCATACCTAGACTGTGTGTTTCATATTTTTTTGGAAAGAGAAGTGAACATCCAGCCCCAATC
  ATGGTATCATTCGGTCTGTCCTCAGCGTGGCTTGGACGGGGCCTGTGTCAGAGTGGTCAGTGCTGACCCC
  TGGGGCTCTTGGGCAGAAAGATGAGGAGACAGAGGTCCAGGGTGGGTTACATAGCACATCCAGGGCTAAG
  CAAGAAATAATTCAGAGGTCCTACCCTCTGTCTAGGGACCCCCCTCCCAAGCCTGGCCTTGGCCTTGGCA
  CAAAGTCCTCCTTGATAGGAGATCCCACTCACTCCTGGAGGCTGCCCCTGAGGCTTGGCCCAGCTCTAGG
  AGCAGTCCCCAGGGTCAGGGAGCCCCTGGTGTGGAAAGAGGCCCCAAGGTAGTAAACCCTGCCCCTGTTA
  CTGTGCTCCAGAGACCTCCTAAGGGAAGGGACAGTTCCTGGAAGGCCCTCCAGCTGGATGCTGGGGATCA
  GCGATAGGTGAGGGGACACAGTGTAGGAGCTCCCCATGTAGAAAAGGGAATGTGGGGAGGGCGTTAGGAG
  CTTGCAGGCATTAGGACTGTCCTGAGCAAGGTCTGCAGCCCCCAGCTCTGCTCACCCCGAATCCTGCCCC
  TTGTTTCCACACCTACCATTCCTCCTCTCCTGATCCCCAGCATCCAGCTGAGGTCCAAGGTCTTTGTCCT
  AGAATCAGAGTGGGGAGGGGACAGCCTGGGGCTGCCCAGAGACTGTGGGTGGAGCTGCCTGCTGCACTCA
  GCAGTGCGGTCAGAGAAGGGCTTTTGGTCTTGAAGTCCAGGTACCATCCCCCCTTAGCATACAGGGGGAA
  GGGCCTGAGAGGAATGTAAGGAAACCAGCCCAGATCAGTCCCAAGGCCAGAGTCCTTTGTCCTACATCTC
  CCTGAACCAGAGTGTGCCCTGCCCCTCATGCTCAGACCTCTCCCACCCCAAACCCTCTCCCGGGACTCAG
  TCTCCCTGGCCACTGCGTATCAGGCTTCTGGGGAAAGCATCCATCACAGAACCTCCCCTTCCCTGCCACG
  CACCTTCCTTGGCCAGCTCCATTCTGGCCTCCTCCACCACCTGCCTTGTGACCACATCTCCCACCACGTC
  CCCAGATCTCAAGAACGCAGCTCAGCTTCTCCTTCGAGCTTGACTCTGAGAGGGAAAGTGACGGAAACCA
  AGTCAGATGAGATGACTGCCATGTACACTGCAGTCAAGGGCAGGGAGGGGAGGAATGACACAAATGGCAG
  GGAGCTGCTGGGGGACTGACCCCTCGGCGCCTGGCCTGGCCGGTGCTGCACATCCACCGGGGCACAACAG
  GGACTTGTCCAGCCTCTGGTCAGAGGATGTGGCCACCTGACCCTAAATAGGTTCCCCAGAGTCCTGCCCC
  TCTAATGAATGAGAACTGCAGGAGTTTCTCCTCTGGGTGCCTGAAGCTATAGTGCAATGGTTCCCAACCC
  TGCATGCACATTCGAATCACCTGGGGGCACAATGCCTAGGCTCCAACCCCAGACACTCTTATTTCATTGG
  TCTGGGTGGACCTGGCATCAGAAGTCATGTAGCTCCTCAGGGGACTGTAGTGTGTGGTCAGCACTGAGGG
  CTCCTCTATGAGGCCTCAAGCCCAGGTGACTCTGTGAGGTCTGCAGAGGGAGAAAAGAACCCACAAGGGA
  AGAGGTGGAGGTCAGGCACGGTGGCTCACGCTTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGTAGAT
  ACCTGAAGTCAGGAGTTCGAGACTAGCCTGGCCAATATGGTAAAACCCCGTGTCTATTAAAAATACAAAA
  ATTAGCTGGCTGTGGTGGTGGGCACCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTG
  AACTCGGGAGGTGGAGGTTGCAGTCAGCCAAGATCGTGCCACTGCACACCATCCTGGATGACAGAGCAAG
  ACTCCATCAC
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_148960.2
• Summary: The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2010]
• Locus ID: 149461