TGF beta Receptor II (TGFBR2) (NM_001024847) Human 3' UTR Clone

CAT#: SC219094

3`UTR clone of transforming growth factor beta receptor II (70/80kDa) (TGFBR2) transcript variant 1 for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: TGFBR2
• Synonyms: AAT3; FAA3; LDS1B; LDS2; LDS2B; MFS2; RIIC; TAAD2; TBR-ii; TBRII; TGFbeta-RII; TGFR-2
• ACCN: NM_001024847
• Insert Size: 2569
• Sequence Data:
  Insert Sequence

  >SC219094 3'UTR clone of NM_001024847
  The sequence shown below is from the reference sequence of NM_001024847. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  AGATTCCTGAAGACGGCTCCCTAAACACTACCAAATAGCTCTTCTGGGGCAGGCTGGGCCATGTCCAAAG
  AGGCTGCCCCTCTCACCAAAGAACAGAGGCAGCAGGAAGCTGCCCCTGAACTGATGCTTCCTGGAAAACC
  AAGGGGGTCACTCCCCTCCCTGTAAGCTGTGGGGATAAGCAGAAACAACAGCAGCAGGGAGTGGGTGACA
  TAGAGCATTCTATGCCTTTGACATTGTCATAGGATAAGCTGTGTTAGCACTTCCTCAGGAAATGAGATTG
  ATTTTTACAATAGCCAATAACATTTGCACTTTATTAATGCCTGTATATAAATATGAATAGCTATGTTTTA
  TATATATATATATATATCTATATATGTCTATAGCTCTATATATATAGCCATACCTTGAAAAGAGACAAGG
  AAAAACATCAAATATTCCCAGGAAATTGGTTTTATTGGAGAACTCCAGAACCAAGCAGAGAAGGAAGGGA
  CCCATGACAGCATTAGCATTTGACAATCACACATGCAGTGGTTCTCTGACTGTAAAACAGTGAACTTTGC
  ATGAGGAAAGAGGCTCCATGTCTCACAGCCAGCTATGACCACATTGCACTTGCTTTTGCAAAATAATCAT
  TCCCTGCCTAGCACTTCTCTTCTGGCCATGGAACTAAGTACAGTGGCACTGTTTGAGGACCAGTGTTCCC
  GGGGTTCCTGTGTGCCCTTATTTCTCCTGGACTTTTCATTTAAGCTCCAAGCCCCAAATCTGGGGGGCTA
  GTTTAGAAACTCTCCCTCAACCTAGTTTAGAAACTCTACCCCATCTTTAATACCTTGAATGTTTTGAACC
  CCACTTTTTACCTTCATGGGTTGCAGAAAAATCAGAACAGATGTCCCCATCCATGCGATTGCCCCACCAT
  CTACTAATGAAAAATTGTTCTTTTTTTCATCTTTCCCCTGCACTTATGTTACTATTCTCTGCTCCCAGCC
  TTCATCCTTTTCTAAAAAGGAGCAAATTCTCACTCTAGGCTTTATCGTGTTTACTTTTTCATTACACTTG
  ACTTGATTTTCTAGTTTTCTATACAAACACCAATGGGTTCCATCTTTCTGGGCTCCTGATTGCTCAAGCA
  CAGTTTGGCCTGATGAAGAGGATTTCAACTACACAATACTATCATTGTCAGGACTATGACCTCAGGCACT
  CTAAACATATGTTTTGTTTGGTCAGCACAGCGTTTCAAAAAGTGAAGCCACTTTATAAATATTTGGAGAT
  TTTGCAGGAAAATCTGGATCCCCAGGTAAGGATAGCAGATGGTTTTCAGTTATCTCCAGTCCACGTTCAC
  AAAATGTGAAGGTGTGGAGACACTTACAAAGCTGCCTCACTTCTCACTGTAAACATTAGCTCTTTCCACT
  GCCTACCTGGACCCCAGTCTAGGAATTAAATCTGCACCTAACCAAGGTCCCTTGTAAGAAATGTCCATTC
  AAGCAGTCATTCTCTGGGTATATAATATGATTTTGACTACCTTATCTGGTGTTAAGATTTGAAGTTGGCC
  TTTTATTGGACTAAAGGGGAACTCCTTTAAGGGTCTCAGTTAGCCCAAGTTTCTTTTGCTTATATGTTAA
  TAGTTTTACCCTCTGCATTGGAGAGAGGAGTGCTTTACTCCAAGAAGCTTTCCTCATGGTTACCGTTCTC
  TCCATCATGCCAGCCTTCTCAACCTTTGCAGAAATTACTAGAGAGGATTTGAATGTGGGACACAAAGGTC
  CCATTTGCAGTTAGAAAATTTGTGTCCACAAGGACAAGAACAAAGTATGAGCTTTAAAACTCCATAGGAA
  ACTTGTTAATCAACAAAGAAGTGTTAATGCTGCAAGTAATCTCTTTTTTAAAACTTTTTGAAGCTACTTA
  TTTTCAGCCAAATAGGAATATTAGAGAGGGACTGGTAGTGAGAATATCAGCTCTGTTTGGATGGTGGAAG
  GTCTCATTTTATTGAGATTTTTAAGATACATGCAAAGGTTTGGAAATAGAACCTCTAGGCACCCTCCTCA
  GTGTGGGTGGGCTGAGAGTTAAAGACAGTGTGGCTGCAGTAGCATAGAGGCGCCTAGAAATTCCACTTGC
  ACCGTAGGGCATGCTGATACCATCCCAATAGCTGTTGCCCATTGACCTCTAGTGGTGAGTTTCTAGAATA
  CTGGTCCATTCATGAGATATTCAAGATTCAAGAGTATTCTCACTTCTGGGTTATCAGCATAAACTGGAAT
  GTAGTGTCAGAGGATACTGTGGCTTGTTTTGTTTATGTTTTTTTTTCTTATTCAAGAAAAAAGACCAAGG
  AATAACATTCTGTAGTTCCTAAAAATACTGACTTTTTTCACTACTATACATAAAGGGAAAGTTTTATTCT
  TTTATGGAACACTTCAGCTGTACTCATGTATTAAAATAGGAATGTGAATGCTATATACTCTTTTTATATC
  AAAAGTCTCAAGCACTTATTTTTATTCTATGCATTGTTTGTCTTTTACATAAATAAAATGTTTATTAGAT
  TGAATAAAGCAAAATACTCAGGTGAGCATCCTGCCTCCTGTTCCCATTC
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_001024847.2
• Summary: The protein encoded by this gene is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with TGF-beta receptor type-1, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of genes related to cell proliferation, cell cycle arrest, wound healing, immunosuppression, and tumorigenesis. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Aug 2017]
• Locus ID: 7048