Mvk (NM_023556) Mouse Untagged Clone

CAT#: MC200602

Mvk (untagged) - Mouse mevalonate kinase (Mvk), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Mvk
• Synonyms: 2310010A05Rik; AI256848; AI414037; MK
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC005606 sequence for NM_023556
  GGAGAAGACCGGGAGCTGCGGCCCGGGTTTCAGCTCACTTGGGCGCTGGCCGGGGCAGAAGTCTCAGAAG CCATGTTGTCAGAAGCCCTGCTGGTGTCCGCCCCGGGGAAGGTCATCCTCCATGGAGAACACGCTGTGGT CCATGGCAAGGTCGCTCTGGCAGCGGCCTTGAACTTGAGAACTTTCCTCCTGCTGCGACCGCAGAGCAAT GGGAAAGTGAGCGTCAATTTACCCAACATCGGTATTAAGCAGGTGTGGGATGTGGGCATGCTTCAGCGAC TGGACACGAGCTTTCTTGAGCAAGGTGATGTCTCGGTACCCACCTTGGAGCAACTGGAGAAGCTAAAGAA GATGGGGGACCTCCCCAGAGACCGTGCAGGCAATGAAGGCATGGCTCTGCTTGCCTTTCTCTACCTGTAC CTGGCAATCTGCCGGAAGCAGAGGACACTCCCGAGCCTGGACATGGTGGTGTGGTCGGAACTTCCCCCCG GGGCAGGCTTGGGCTCCAGCGCCGCCTACTCTGTGTGTCTGGCAGCCGCCCTCCTGACTGCCTGTGAGGA GGTCTCCAACCCGCTCAAGGACGGGGTCTCCGTCAGCAGGTGGCCCGAGGAAGATCTGAAGTCAATCAAC AAGTGGGCCTTCGAAGGGGAGAGAGTGATCCATGGGAACCCTTCTGGTGTGGACAATGCCGTCAGCACCT GGGGCGGAGCCCTGCGCTTCCAGCAAGGGACGATGTCTTCCTTGAAGAGCCTCCCGTCTCTGCAGATCCT GCTCACCAACACCAAGGTCCCGCGGAGTACCAAGGCCCTTGTGGCTGCTGTCAGAAGCAGGCTGACCAAG TTCCCTGAGATTGTGGCCCCGCTGCTGACCTCCATTGACGCAATATCCCTGGAGTGTGAGCGCGTGCTAG GGGAGATGGTGGCAGCTCCAGTTCCGGAACAGTACCTCGTACTAGAAGAGCTGATAGACATGAACCAGCA CCATCTGAATGCTCTCGGGGTGGGCCACAACTCCCTGGACCAGCTCTGCCAAGTAACGGCAGCACACGGA CTGCACAGCAAGCTGACGGGCGCTGGCGGTGGCGGCTGTGGCATCACCCTCCTGAAGCCAGGTCTAGAGC AAGCCACAGTGGAGGCAGCCAAGCAGGCCCTGACCAGCTGCGGGTTTGACTGCTGGGAGACCAGCATCGG CGCACCCGGAGTTTCCACACACTCAGCTGCAGCTGTAGGGGACCCTGTCCGACAAGCCCTGGGCCTCTGA GACCACCCGACACACCATCCTACCAAGAAGCCTCTAAGTATCTGGGGCTGGAGTTGGCCTGCACCTTCTA GACTCTGACCTCATCCGTGTTCTGCCGTTTCTGAAGCCAGGCAGGGATTAGTTGTGGGGTCTTCTGAGAT GGCAGGCTGACACAGGAGGCCTTCGCCCTGGAGCTCCTATGGGCACATCGGCCTCACACAAACTCTCTGG CTCCTAGCCACGCACTCTTCTGTCCAGCCACGATGTCCCCTAAGGAACCACCTGGCCAGCAGCTCGTGGC TCCTGGCTCCTGGCTCTTGCCCTCTCTCGGAGATCATCAGCTGAGGCAAGGCATGCCGACTGCCTGTCTC CGTGTGGAAAAGCTGCTGTGGGGGAAATAAAAAGAAATAGTACAAACAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_023556
• ORF Size: 1188 bp
• Insert Size: 1188
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: BC005606, AAH05606
• RefSeq Size: 1712
• RefSeq ORF: 1188
• Locus ID: 17855
• Gene Summary: This gene encodes mevalonate kinase, a key enzyme involved in the biosynthesis of cholesterol and non-sterol isoprenes. The complete lack of encoded protein is lethal to mouse embryos. Mice lacking one allele of this gene exhibit increased levels of mevalonate in spleen, heart and kidney, as well as increased levels of serum immunoglobulins A and D. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
  Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1.