Cldn3 (BC012650) Mouse Untagged Clone

CAT#: MC200803

Cldn3 (untagged) - Mouse claudin 3 (cDNA clone MGC:13769 IMAGE:4217040), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Cldn3
• Synonyms: AI182374|Cpetr2|mRVP1
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC012650
  CCACGCGTCCGCCCTGAGCTGCCCGGCCGAGCCGGTTCAAGTCCAGCAGCCATGTCCATGGGCCTGGAGA TCACCGGCACGTCGCTGGCCGTGCTGGGCTGGCTGTGCACCATCGTGTGCTGCGCCCTTCCCATGTGGCG CGTTTCGGCCTTCATCGGCAGCAGCATCATCACGGCGCAGATCACCTGGGAGGGCCTGTGGATGAACTGC GTGGTGCAGAGCACCGGTCAGATGCAGTGCAAAATGTACGACTCGCTGCTGGCCGCCTTCGGGCTCCTCG TGGCGCTCGTGGGCGCCCAGTGTACCAACTGCGTACAAGACGAGACGGCCAAGGCCAAGATCACCATCGT GGCGGGAGTGCTTTTCCTGTTGGCGGCTCTGCTCACCTTAGTACCGGTGTCCTGGTCGGCCAACACCATC ATCAGGGATTTCTATAACCCGTTGGTGCCCGAGGCCCAGAAGCGGGAGATGGGAGCTGGGTTGTACGTGG GCTGGGCTGCCGCCGCGCTGCAGTTGCTAGGGGGCGCCTTGCTGTGTTGCTCCTGCCCACCGCGCGACAA GTATGCACCCACCAAGATCCTCTATTCTGCGCCGCGATCCACCGGCCCTGGCACCGGTACCGGCACCGCC TACGACCGCAAGGACTACGTCTGAGGGGCCGGGTGCACGCAGACCGTACCGTCACCACTACCAGCAGTCG ATGAACCCCACCCGTCCAGCGTGCAGCCTCGCGTCTGAGACTACCGGGCCTAGGAACTGTCCAAGCCGAA TGGACAAAGAAACCTCGCCCTTCCCAAGAACTGGGCTGGGGTGGCCACTGCAGCTACTTGCCAGCCCCGC AGAAGCTCACAGTGGGCAGAGACAGGCAAACCATGAAACGGGCCATTTCATATTTTTCAATAAAAGTCTT TCGTTTTTTGCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: BC012650
• ORF Size: 603 bp
• Insert Size: 603
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: BC012650, AAH12650
• RefSeq Size: 999
• RefSeq ORF: 603
• Locus ID: 12739
• Gene Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a low-affinity receptor for clostridium perfringens enterotoxin (CPE) produced by the bacterium Clostridium perfringens, and the interaction with CPE results in increased membrane permeability by forming small pores in plasma membrane. This protein is highly overexpressed in uterine carcinosarcoma. This protein is also predominantly present in brain endothelial cells, where it plays a specific role in the establishment and maintenance of blood brain barrier tight junction morphology. [provided by RefSeq, Aug 2012]