Tgfb2 (NM_009367) Mouse Untagged Clone

CAT#: MC200993

Tgfb2 (untagged) - Mouse transforming growth factor, beta 2 (Tgfb2), (10ug)


  "NM_009367" in other vectors (4)

Reconstitution Protocol

USD 210.00

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Size
    • 10 ug

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Specifications

Product Data
Type Mouse Untagged Clone
Tag Tag Free
Symbol Tgfb2
Synonyms BB105277; Tgf-beta2; Tgfb-2
Vector PCMV6-Kan/Neo
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>BC011170 sequence for NM_009367
CTGCTTTGCAAAAGTTTCGTATTAAAAACAACTCTACCTGACCGCTCTGAGAATTACTAGTTTCTTTTTT ATATATATTTTTTCTTACTTTAAATAACAACATCAACGTTTCTTCCTTTTAAAAACATGCACTACTGTGT GCTGAGCACCTTTTTGCTCCTGCATCTGGTCCCGGTGGCGCTCAGTCTGTCTACCTGCAGCACCCTCGAC ATGGATCAGTTTATGCGCAAGAGGATCGAGGCCATCCGCGGGCAGATCCTGAGCAAGCTGAAGCTCACCA GCCCCCCGGAAGACTATCCGGAGCCGGATGAGGTCCCCCCGGAGGTGATTTCCATCTACAACAGTACCAG GGACTTACTGCAGGAGAAGGCAAGCCGGAGGGCAGCCGCCTGCGAGCGCGAGCGGAGCGACGAGGAGTAC TACGCCAAGGAGGTTTATAAAATCGACATGCCGTCCCACCTCCCCTCCGAAAATGCCATCCCGCCCACTT TCTACAGACCCTACTTCAGAATCGTCCGCTTTGATGTCTCAACAATGGAGAAAAATGCTTCGAATCTGGT GAAGGCAGAGTTCAGGGTCTTCCGCTTGCAAAACCCCAAAGCCAGAGTGGCCGAGCAGCGGATTGAACTG TATCAGATCCTTAAATCCAAAGACTTAACATCTCCCACCCAGCGCTACATCGATAGCAAGGTTGTGAAAA CCAGAGCGGAGGGTGAATGGCTCTCCTTCGACGTGACAGACGCTGTGCAGGAGTGGCTTCACCACAAAGA CAGGAACCTGGGGTTTAAAATAAGTTTACACTGCCCCTGCTGTACCTTCGTGCCGTCTAATAATTACATC ATCCCGAATAAAAGCGAAGAGCTCGAGGCGAGATTTGCAGGTATTGATGGCACCTCTACATATGCCAGTG GTGATCAGAAAACTATAAAGTCCACTAGGAAAAAAACCAGTGGGAAGACCCCACATCTCCTGCTAATGTT GTTGCCCTCCTACAGACTGGAGTCACAACAGTCCAGCCGGCGGAAGAAGCGCGCTTTGGATGCTGCCTAC TGCTTTAGAAATGTGCAGGATAATTGCTGCCTTCGCCCTCTTTACATTGATTTTAAGAGGGATCTTGGAT GGAAATGGATCCATGAACCCAAAGGGTACAATGCTAACTTCTGTGCTGGGGCATGCCCATATCTATGGAG TTCAGACACTCAACACACCAAAGTCCTCAGCCTGTACAACACCATAAATCCCGAAGCTTCCGCTTCCCCT TGCTGTGTGTCCCAGGATCTGGAACCACTGACCATTCTCTATTACATTGGAAATACGCCCAAGATCGAAC AGCTTTCCAATATGATTGTCAAGTCTTGTAAATGCAGCTAAAGTCCTTGGGAAAGCCAGGACACGAAAAT CACGGTGACAATGACATATAATGACAACGATGACGACCATGATGTTTGTGACAGGAGGGAGGGAGTTTTG ATTCATCAGTGTTTAAAAAAAAAAAAATTGGAGAAAAAAAATCGGTACTAGTTCAAACATTTTGCAAGCT TGTGTTCTGTTTGTTAAAACTGGCATCTGAGATTACAGCAACAACAACCACAAAAATGGAAGGCGTTAGT CTGCATCTCACCTACTTCCTAAGAGACACAAAAAGAAAACATCTTTTTTTTTTTTTTAAGGAAAAAAATA AACACTGGAAGAATTTGTTAGTGTTAATTATGTGAAAAAAAAAAAAAAAAAAAAAAAAAAA
Restriction Sites RsrII-NotI     
ACCN NM_009367
ORF Size 1245 bp
Insert Size 1245
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Reference Data
RefSeq BC011170, AAH11170
RefSeq Size 1741
RefSeq ORF 1245
Locus ID 21808
Gene Summary This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. Mice lacking a functional copy of this gene display developmental defects in multiple organs and perinatal lethality. Heterozygous mutant mice exhibit aortic root aneurysm. This gene encodes multiple isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Aug 2016]
Transcript Variant: This variant (1) represents the shorter transcript and encodes the shorter isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.

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