Lefty1 (NM_010094) Mouse Untagged Clone

CAT#: MC202041

Lefty1 (untagged) - Mouse left right determination factor 1 (Lefty1), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Lefty1
• Synonyms: AI450052; Ebaf; Leftb; lefty; lefty-1; Stra3; Tgfb4
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC050221 sequence for NM_010094
  CACACATCCAAGGCTCCTCTTCCCGGACAGCACCATGCCATTCCTGTGGCTCTGCTGGGCACTCTGGGCA CTGTCGCTGGTTAGCCTCAGGGAAGCCCTGACCGGAGAGCAGATCCTGGGCAGCCTGCTGCAACAGCTGC AGCTCGATCAACCGCCAGTCCTGGACAAGGCTGATGTGGAAGGGATGGTCATCCCCTCGCACGTGAGGAC TCAGTATGTGGCCCTGCTACAACACAGCCATGCCAGCCGCTCCCGAGGCAAGAGGTTCAGCCAGAACCTT CGAGAGGTGGCAGGCAGGTTCCTGGTGTCAGAGACCTCCACTCACCTGCTAGTGTTCGGAATGGAGCAGC GGCTGCCGCCTAACAGCGAGCTGGTGCAGGCTGTGCTGCGGCTGTTCCAGGAGCCTGTGCCCAGAACAGC TCTCCGGAGGCAAAAGAGGCTGTCCCCACACAGTGCCCGGGCTCGGGTCACCATTGAATGGCTGCGCTTC CGCGACGACGGCTCCAACCGCACTGCCCTTATCGATTCTAGGCTCGTGTCCATCCACGAGAGCGGCTGGA AGGCCTTCGACGTGACCGAGGCCGTGAACTTCTGGCAGCAGCTGAGCCGGCCGAGGCAGCCGCTGCTGCT CCAGGTGTCGGTGCAGAGGGAGCATCTGGGGCCGGGAACCTGGAGCTCACACAAGTTGGTTCGTTTCGCG GCGCAGGGGACGCCGGATGGCAAGGGGCAGGGCGAGCCACAGCTGGAGCTGCACACGCTGGACCTCAAGG ACTATGGAGCTCAAGGCAATTGTGACCCCGAGGCACCAGTGACTGAAGGCACCCGATGCTGTCGCCAGGA GATGTACCTGGACCTGCAGGGGATGAAGTGGGCCGAGAACTGGATCCTAGAACCGCCAGGGTTCCTGACA TATGAATGTGTGGGCAGCTGCCTGCAGCTACCGGAGTCCCTGACCAGCAGGTGGCCATTTCTGGGGCCTC GGCAGTGTGTCGCCTCAGAGATGACCTCCCTGCCCATGATTGTCAGCGTGAAGGAGGGAGGCAGGACCAG GCCTCAAGTGGTCAGCCTGCCCAACATGAGGGTGCAGACCTGTAGCTGCGCCTCAGATGGGGCGCTCATA CCCAGGAGGCTGCAGCCATAGGCGCGGGGTGTGGCTTCCCCAAGGATGTGCCTTTCATGCAAATCTGAAG TGCTCATTATACTGGGAGAGCTGGGGATTCTAACTCCCTAATGGGCAATCCCTGTGTGTGCTCTTTGCTT CCTCTGAAGTAGCCTCATCCCTAAATTTTTACCTTCGAGGAATGTGACTCGCTGGCCCCTGGAGGCGCTC TGACCCAGTGGTCTCTGTCCTTCATATTGTTCACTGCACTGTATGCGAAGCACTTACATGTATAGATACT GCAAACCAAGGACAGAATCCCCAATTGCCATTGTTCCCTTAATTTGTCGCTGAATCTGGGCTGAGTCCCA GTCTTGACTCTGGACCTAAGCCACAAGTTGGGCAAACATGTCCAACCTAGGCAATACTGGCTTTGCTAGA TGTGAATAAAATATGCTTTGTTTTGTAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_010094
• ORF Size: 1107 bp
• Insert Size: 1107
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: BC050221, AAH50221
• RefSeq Size: 1582
• RefSeq ORF: 1107
• Locus ID: 13590
• Gene Summary: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in left-right asymmetry determination of organ systems during development. Mice lacking a functional copy of this gene exhibit embryonic lethality and defects in left-right patterning. [provided by RefSeq, Aug 2016]