Icosl (NM_015790) Mouse Untagged Clone

CAT#: MC202216

Icosl (untagged) - Mouse icos ligand (Icosl), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Icosl
• Synonyms: AU044799; B7-H2; B7h; B7RP-1; BG071784; GI50; GL50; GL50-B; ICOS-L; Icoslg; LICOS; Ly115l; mKIAA0653
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC029227 sequence for NM_015790
  AGCGGGTCTCCTGCCGCCAAAGCCTCAAGAACCCCAGATTTCAGCGCCCCAAGCCTGGAAGCTCCCCAGT TCTTCGTGGCCCCCAACAGCTCCGGAACCCCAGCCGCTGCAACTCTCCGCGTCCGAAATCCAGCACCCCG CAGTCTGCGCTCGCACCATGCAGCTAAAGTGTCCCTGTTTTGTGTCCTTGGGAACCAGGCAGCCTGTTTG GAAGAAGCTCCATGTTTCTAGCGGGTTCTTTTCTGGTCTTGGTCTGTTCTTGCTGCTGTTGAGCAGCCTC TGTGCTGCCTCTGCAGAGACTGAAGTCGGTGCAATGGTGGGCAGCAATGTGGTGCTCAGCTGCATTGACC CCCACAGACGCCATTTCAACTTGAGTGGTCTGTATGTCTATTGGCAAATCGAAAACCCAGAAGTTTCGGT GACTTACTACCTGCCTTACAAGTCTCCAGGGATCAATGTGGACAGTTCCTACAAGAACAGGGGCCATCTG TCCCTGGACTCCATGAAGCAGGGTAACTTCTCTCTGTACCTGAAGAATGTCACCCCTCAGGATACCCAGG AGTTCACATGCCGGGTATTTATGAATACAGCCACAGAGTTAGTCAAGATCTTGGAAGAGGTGGTCAGGCT GCGTGTGGCAGCAAACTTCAGTACACCTGTCATCAGCACCTCTGATAGCTCCAACCCGGGCCAGGAACGT ACCTACACCTGCATGTCCAAGAATGGCTACCCAGAGCCCAACCTGTATTGGATCAACACAACGGACAATA GCCTAATAGACACGGCTCTGCAGAATAACACTGTCTACTTGAACAAGTTGGGCCTGTATGATGTAATCAG CACATTAAGGCTCCCTTGGACATCTCGTGGGGATGTTCTGTGCTGCGTAGAGAATGTGGCTCTCCACCAG AACATCACTAGCATTAGCCAGGCAGAAAGTTTCACTGGAAATAACACAAAGAACCCACAGGAAACCCACA ATAATGAGTTAAAAGTCCTTGTCCCCGTCCTTGCTGTACTGGCGGCAGCGGCATTCGTTTCCTTCATCAT ATACAGACGCACGCGTCCCCACCGAAGCTATACAGGACCCAAGACTGTACAGCTTGAACTTACAGACCAC GCCTGACAGGACTCTGCCCAGGATATGGACAGGGTTTCTGTGAGTTGCCACCAGGTGGATGTCAGACACA ACTTCAGAGTGGACCCCCACAGGCCTGGTGACAGAGGACAACGAGCTGTCTGCTTATGGGCTGTGATGGA GGCCAGGAATCCCTGGCTTTACGAGGCACAGAGACTTCATCCCAGAAACCCCGAGGGAGATCTCTCCAGT GGGCAGCAGCAACATCATCGGAATATGGAGCCTCCGGTGAGCTGTCGGCACAGAGAGCAGCAGCTTGTGA GAAGATCCTTCCTTGGCACGTTACTACTCAGGCCTAGGAGCTTTATAAAAGAGCGTTTGAGCCACTCTGA AAGCCCTACAGAGTCTACTGGAGACTTTCCCTGCAGGACCTTCAGTTGGGGAGGAAGCCTGACTTTATTT AGGTCTCAGGCTACTTGGGCCTCTTCGAGGATATGTGGGATTTTGTCTACTGCAAACCTGTTTCTGGCTG ACAATGGTTGGGCTCAGAGGCACTCAGCTTCACAACATCAATGGGACACGCCTCATCCTTGACTTCCTGT GGCTACAGAAGCTTTCCGAAAGCCTTGAGCTCTTTCAGACTGAACAGCTCTGCCCAGTCTCAGCAGCCCA TGAAGATCTCAACTCCAGCTTCCTGGGTCTCCGTGTTGCTGGCCAGAATAGAGCTAGCTCTTTTGTTTCA AGATGGTTCTGCAAAGTTGGCTGCTTGGAAACCTAGGGATGTATGTACAAGCTCCAGGCTGATGCAGTAG GGGGCACGGACTCCCCGATGGAACACAGTATCTGACCCTAGGTGAGGGCAAGCTCCTTCCCACGCAGAGG ACTGGAAATTCTGGACCGTCAAGGCCTGTCTGCTATGTGGCTGGGGCTCAGTGCTGATGGATGTGTGAGA TCTCAGGAATGAGGAGTGAGAACCCTGGGCTCAGGACTAGGAAGACCTGTCCATTTTTTTTTTTTTTTAA TGCCCACATGGACTTTTTATTCTTCACACCGATGTATTCAATGAGTGTAGAGAGAACTACTTAAGTCCTT CCCGAGTACAAAGCATTACCTACCTGCAGAATAGCAACTGTTGTTATGGGTCTTGAGTTGGCAGCTACAG CAAACAAGCACAAGGAGCAGTTGGGGTGCAAGAAGATGGGGTGCAGCGCCCCCAAGGACAGACATTTGGG AATTAGTGGTCTCCCTGATGCCCATAGTTCCCCAGGAACTCAGGTGGGTCTGCGGCAGCACAGTAGGAGT ATTCCTCCTACTTTAACTTTTCTTGTCAGACGTAGTTTAGGTTCAGAAAGAGGTCAACTCAGCAAGCCAG CTAGCCGCCTTGGGGCACCAGACACACTGCCCCCCACCCCCTGCTTATGTAGGCATTGGGAACCCTTCAC AGACCACTGGCTGTACAGTCACCATCACCTGCTGATTCCAGCAGGCCCCCACCTTCTTGTGGAATCCTGG GAGCACTCCCCTCTTACCCCTCACTGCCCCCCACCCCCTGCACATCAGCATTCATTAGATTTGCCCTGTA ACGTCTGATTCCTCCTTTATCTGGGTTGTAGATGGGGCATAGTGACTTTTAGAAACCTAACAAGGGAATA AATGTAAGATGTGCTTTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_015790
• ORF Size: 969 bp
• Insert Size: 969
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: BC029227, AAH29227
• RefSeq Size: 2803
• RefSeq ORF: 969
• Locus ID: 50723
• Gene Summary: Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function. During pregnancy, may function to skew the cytokine of maternal T-cells toward immunoprotective Th2 phenotype. [UniProtKB/Swiss-Prot Function]