Furin (NM_001081454) Mouse Untagged Clone

CAT#: MC202300

Furin (untagged) - Mouse furin (paired basic amino acid cleaving enzyme) (Furin), transcript variant 2, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Furin
• Synonyms: 9130404I01Rik; Fur; PACE; Pcsk3; SPC1
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC048234 sequence for NM_001081454
  GCCCCGGGACCCTGGCACTGAGCAGGCACGTGGCAGCCAAGGCCCTGTGACCAGGCCAGGGAGACAGGCG CTCTGGGGTTCCAGTCACCTGCCCCCCCATGGAGCTGAGATCCTGGTTGCTATGGGTGGTCGCAGCAGCA GGAGCCGTGGTCCTGCTGGCAGCTGATGCTCAAGGCCAGAAGATCTTCACCAACACCTGGGCCGTGCACA TTCCTGGAGGCCCAGCTGTGGCTGATAGGGTGGCGCAGAAGCATGGCTTCCACAACCTGGGCCAGATCTT CGGTGACTATTACCACTTCTGGCACAGAGCAGTGACAAAGCGGTCCCTGTCGCCTCACCGCCCGCGGCAC AGCCGGCTACAGAGGGAGCCTCAAGTAAAGTGGCTGGAGCAGCAGGTAGCCAAGCGAAGAGCCAAGAGGG ACGTGTATCAGGAGCCCACGGACCCCAAGTTCCCCCAGCAGTGGTACCTGTCTGGTGTCACTCAGCGAGA CCTGAATGTGAAGGAGGCCTGGGCCCAGGGCTTCACAGGCCATGGCATTGTGGTCTCCATCCTGGATGAC GGCATTGAGAAGAATCATCCCGACCTAGCAGGCAATTATGACCCTGGAGCCAGTTTTGACGTGAATGACC AGGACCCCGACCCACAGCCTCGGTACACACAGATGAATGACAACAGGCATGGCACTCGCTGTGCCGGGGA AGTGGCAGCAGTGGCCAACAATGGTGTCTGTGGCGTAGGTGTAGCTTACAATGCCCGAATTGGAGGGGTG CGGATGTTGGATGGCGAGGTGACTGATGCAGTAGAGGCACGTTCGCTGGGCCTGAATCCCAACCACATCC ACATCTACAGCGCCAGCTGGGGCCCTGAGGACGACGGCAAGACCGTGGATGGACCAGCCCGGCTCGCTGA GGAGGCCTTCTTTCGGGGAGTTAGCCAGGGCCGAGGAGGGCTGGGCTCCATCTTTGTCTGGGCCTCAGGG AATGGGGGCCGGGAACATGACAGCTGCAACTGTGACGGCTACACCAACAGCATCTATACACTGTCCATCA GCAGCGCCACACAGTTCGGCAATGTGCCCTGGTACAGTGAGGCCTGCTCCTCCACACTGGCCACCACCTA CAGCAGCGGCAACCAGAATGAGAAGCAGATCGTGACAACTGACCTGAGGCAGAAGTGCACAGAATCTCAC ACAGGCACCTCGGCTTCTGCCCCCTTGGCAGCTGGTATCATTGCTCTCACCCTGGAGGCCAACAAGAACC TCACCTGGCGGGACATGCAGCACCTGGTAGTGCAGACCTCAAAGCCAGCCCACCTCAACGCTGATGATTG GGCTACCAACGGCGTGGGCCGGAAAGTGAGCCATTCGTATGGCTACGGGCTGTTGGATGCAGGTGCCATG GTGGCTCTGGCCCAGAACTGGACAACAGTGGCCCCCCAGCGGAAGTGCATTGTTGAAATCCTGGTGGAAC CCAAGGACATCGGCAAACGGCTAGAGGTGCGCAAGGCGGTGACAGCATGCCTGGGTGAGCCCAACCACAT CACCAGGCTGGAACACGTTCAGGCCCGGCTCACCCTGTCTTACAATCGCCGCGGTGACCTGGCTATCCAC CTCATCAGCCCCATGGGCACCCGCTCCACCCTGTTAGCTGCCAGACCACATGACTACTCTGCTGATGGGT TTAATGATTGGGCTTTCATGACAACCCATTCCTGGGATGAGGATCCGGCTGGCGAATGGGTCCTAGAGAT TGAAAATACCAGTGAAGCCAACAACTATGGGACGCTGACCAAGTTCACTCTCGTTCTGTATGGCACAGCC CCCGAGGGGCTCTCTACACCTCCAGAAAGCAGCGGCTGCAAGACCCTCACATCCAGCCAGGCCTGCGTGG TGTGTGAGGAAGGTTACTCTCTGCACCAGAAAAGCTGTGTCCAGCACTGCCCACCAGGCTTCATCCCCCA AGTCCTTGATACACACTACAGCACTGAGAATGATGTGGAGATCATCCGTGCCAGCGTCTGTACCCCCTGC CACGCCTCATGTGCCACTTGCCAGGGCCCGGCCCCCACAGACTGCCTCAGCTGCCCCAGCCATGCCTCCC TGGACCCAGTGGAGCAGACCTGCTCCCGGCAAAGCCAGAGCAGCCGGGAGTCTCGGCCTCAGCAGCAGCC TCCTGCACTGCGCCCTGAGGTGGAGATGGAGCCCCGGCTGCAGGCTGGGTTGGCCTCTCACCTGCCCGAG GTCCTGGCCGGCCTCAGCTGCCTTATCATCGTGCTCATCTTTGGCATCGTCTTCCTGTTCCTGCATCGGT GTTCGGGCTTCAGCTTCCGGGGAGTGAAAGTGTACACCATGGACCGCGGCCTCATCTCCTACAAGGGGCT GCCCCCTGAAGCCTGGCAGGAGGAGTGCCCATCGGACTCAGAGGAGGACGAGGGCCGGGGCGAGAGGACC GCCTTCATCAAAGACCAGAGCGCCCTTTGAAAAGCCCACTGCCCACCCTATCAAATCGATCCCTTCCTCG GGCACTTTTTAATTCACCAAAGTATTTTTTTATCTTGCGACTGGATTTGGACCCTAGCTGGGAGGCGAGA GGGGCAGAGACTGCTTCTTACCCCACCCTTGGGCCTACCTGTTTGCCTGAGGTGGGATCCCAGGAGCCTC ACCCCTACCACCCCTCCATGTGGAGGAAAGAGGAAATCTTTAGGGCAGCTTCCTTGGCCCAGCTGGACTT CCCGCAGAGTGAAGAGGGGCGGCCTCTCTCTGAGTCCCTGACCAGGCTGCAGCCCTGCCCCTTCCCTTCC CTGCCCCTCAGAAAGCAATAATGGTTCCCATCCAGGCAACAGGGAGGCTGGCCAGGAGGTACTTGAAGAA GGCAGCCACCTCTCCAAGGGCTTTTGCATCCCCTGACCCTCTCTGGCTCACAGGTGAGCCTCCGAAGAAG CTGCAGTCTTAGGAAGGGACCAAAGCAAAGCAGGCCCCTCCCAGTGTGCCTGTACTTTCTTGCTCTCAGC CTGCCTCTGCACTCCAGGCCTCCACCTCCGTGGAAGCCAGGCTGAGCTAGGCCAGCACGGGCCGGCCGAG CTAAAGCTCTGGGGGCCTTGCTGGTGTCTGACCATCCTTTATGGCACCCTCCCCCCTTGCCAGGGCCCTG TTTTCTGAGCCCGGGGCTGCCTGGGCTGTTGGCAGTTACAGTACAGGAGCCCCTGGGTGGGTGGTGGGGA GGCACGGTGGCCCAGCCTTCTCCTCCCGCCTCCCACCCGATGCTGCTTTCCCCTGTGGGGATCTCAGGAG CTGTTTGAGGATATATTTTCACTTTGTGATTATTCACTTTAGATGCTGATTCTTTTTTTTTTTTTTTTTT TGTATTTTTAATGGGGGTAGCAGCTGGACCCTTGACCTTCTCATGCCCACACCCACCCTGCCCTTCCCAT GGCTGCCCAGCCCTGGGGTATAGGGAATAACTAAGCCCCATGTCCTGAAGAGGCAGGCCAGCCCGGTGGG CTCTAAGAAAGGGGGTTGTGGTGGGAGGGGTAGGCTGACATCATCTGTTTCAAATGGGGTTGTGCCAAGG GCTTATGGGTCGCTGGCTCTCCAAGTGCCAGGGGTGGGCAGGTGGCACCACCAAGCCCTTTCTAACACTG TGCCCTGGTGGAGAAAGCATTGGCCTATGATGCCCCCCAAACCCCCTCTTCTGATGTGCCTTTTGCACCC TTCCCATTAGGACAATCAGTCCCCTCCCACTTGGGCTCCCCCCCCCCCATTTTCTTTTCCTTAGCCCTTC TCAGTACCCAGCCTACCTGTCCAGGGGTGCCCCTTGCTCTCCTGCCCACCCCTCACGGCCATCCAGGCTG GTTTTGTAAGATGCTGGGTTGGTGCACAGTGATTTTTTTTTTCCTTGTAATTTAAACAGGCCTGGCATTG TTGGTTCTATTTAATGGACACGAGATAATGTTAGAGGTTTTAAAGTGATTAAACGTGCAGACTATGCAAA CCAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_001081454
• ORF Size: 2382 bp
• Insert Size: 2382
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: BC048234, AAH48234
• RefSeq Size: 4017
• RefSeq ORF: 2382
• Locus ID: 18550
• Gene Summary: This gene encodes a calcium-dependent serine endoprotease that proteolytically activates different proprotein substrates traversing the secretory pathway. The encoded protein undergoes proteolytic autoactivation during which an N-terminal propeptide is cleaved to generate the mature protein. Mice lacking the encoded protein die at an embryonic stage and display hemodynamic insufficiency, cardiac ventral closure defect, axial rotation defect and abnormal yolk sac vasculature. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
  Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.