Eif2ak3 (NM_010121) Mouse Untagged Clone

CAT#: MC203473

Eif2ak3 (untagged) - Mouse eukaryotic translation initiation factor 2 alpha kinase 3 (Eif2ak3), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Eif2ak3
• Synonyms: Pek; Perk
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC054809
  CGGAACCCTCGCTCAATGGGCGATGTCTGCACAAGGCTGTCACTCAGGTGGCAGTGGCTGAGACGTGGCC GGGCAGCTCTGCTGCTGCGGCGCGAAGTCGAGAGGCGGCGGGGTCCGTGGCGCGCGCTCGCAGTGCTCCG AGGCTCCGAGCGGCGAGACGGGCGGGCGCCGACGGCAGGGTCTCCATGCCCGCGCGTGGGGCGGGCCGCT GATGGAGCGCGCCACCCGGCCCGGGCCGCGCGCGCTGCTGCTGCTTCTGTTCCTGCTGCTGGGCTGCGCG GCGGGGATCTCGGCGGTCGCGCCCGCCCGCAGTTTGCTTGCTCCCGCGTCGGAGACAGTGTTTGGCTTAG GGGCAGCGGCCGCCCCGACTTCGGCCGCGCGGGTGCCTGCGGTGGCAACGGCCGAAGTGACCGTGGAGGA CGCCGAGGCATTGCCGGCTGCCGCTGGCGAACCGGAGTCACGCGCGACGGAGCCCGATGACGACGTGGAA CTGCGGCCTCGCGGCAGGTCCTTGGTAATCATCAGCACTTTAGATGGACGAATCGCTGCACTGGATGCCG AGAATGATGGGAAAAAGCAGTGGGATTTGGACGTGGGGTCTGGTTCCTTGGTTTCATCTAGCCTCAGCAA GCCAGAGGTGTTTGGGAACAAGATGATCATCCCCTCCCTGGATGGAGACCTCTTCCAGTGGGACCGGGAC CGAGAGAGCATGGAGGCCGTCCCCTTCACGGTGGAGTCCCTGCTCGAATCTTCCTACAAGTTTGGAGATG ATGTTGTTCTGGTTGGAGGGAAATCTCTGACTACATACGGACTCAGTGCTTACAGTGGAAAGCTGAGGTA TATCTGTTCTGCCTTGGGATGTCGCCGATGGGATAGTGATGAAATGGAAGAAGAGGAAGACATCTTGCTT CTGCAGCGTACGCAGAAGACTGTGCGAGCTGTCGGGCCTCGAAGCGGCAGTGAGAAGTGGAATTTCAGTG TTGGCCACTTTGAACTTCGGTATATTCCAGACATGGAAACTAGAGCCGGATTCATTGAAAGCACCTTTAA ACCGGGTGGAAACAAAGAAGACTCTAAAATTATTTCAGATGTGGAAGAACAAGAAGCCACCATGCTGGAC ACAGTGATAAAAGTTTCCGTTGCTGATTGGAAGGTCATGGCGTTTAGTAGGAAGGGAGGCCGCCTGGAAT GGGAGTACCAGTTTTGTACTCCCATCGCGTCCGCCTGGCTGGTGAGGGATGGCAAGGTCATCCCCATCAG CCTGTTTGATGATACAAGTTACACAGCCAGCGAAGAAGCCTTGGGAGACGAAGAAGACATTGTAGAGGCT GCTCGGGGAGCCACAGAGAACAGCGTGTACTTAGGGATGTACAGAGGCCAGCTGTACCTGCAGTCGTCCG TCAGGGTCTCAGAAAAGTTCCCTACAAGCCCAAAGGCCTTGGAGTCTGTAAATGGCGAAAATGCAATTAT TCCTCTGCCGACGATCAAATGGAAGCCCTTAATCCATTCTCCTTCTAGGACTCCTGTCTTGGTTGGGTCT GATGAATTTGACAAATGTCTAAGTAATGATAAGTATTCCCACGAAGAATACAGTAATGGTGCACTTTCAA TCCTCCAGTATCCATACGATAACGGTTACTATCTGCCATACTACAAGAGAGAAAGGAATAAGCGGAGCAC GCAGATCACAGTCAGGTTCCTGGACAGCCCCCACTACAGCAAGAACATCCGCAAGAAGGACCCTATCCTC CTGCTGCACTGGTGGAAGGAGATATTCGGGACGATCCTGCTTTGCATCGTAGCCACGACCTTCATCGTGC GCAGGCTTTTCCATCCTCAGCCCCACAGGCAGCGGAAGGAGTCTGAAACTCAGTGCCAGACTGAAAGTAA ATACGACTCCGTGAGTGCCGATGTCAGTGACAACAGCTGGAATGACATGAAGTACTCAGGATACGTATCC CGATATCTAACAGATTTTGAGCCAATTCAGTGCATGGGTCGTGGTGGCTTTGGCGTTGTCTTTGAAGCTA AAAACAAAGTAGATGACTGCAATTACGCTATCAAGAGGATCCGGCTCCCCAACAGGGAGTTGGCACGGGA GAAGGTAATGCGGGAAGTTAAAGCCTTGGCTAAGCTGGAACACCCAGGCATTGTGAGGTATTTCAACGCC TGGCTGGAAACCCCACCAGAGAAGTGGCAAGAAGAGATGGATGAGATCTGGCTCAAAGACGAAAGCACAG ACTGGCCGCTCAGCTCCCCTAGCCCGATGGATGCCCCATCTGTTAAGATCCGAAGGATGGATCCTTTCTC TACAAAAGAGCAGATCGAAGTCATAGCTCCTTCTCCTGAAAGAAGTCGGTCTTTCTCGGTGGGCATTTCC TGTGGCCAGACAAGCTCATCGGAGAGCCAGTTCTCTCCCCTGGAGTTCTCAGGGACAGACTGCGGAGACA ACAGTGACTCAGCGGACGCAGCCTACAACCTCCAGGACAGTTGCCTGACGGACTGCGAGGACGTGGAAGA TGGCACCGTGGACGGCAATGACGAGGGACACTCCTTTGAACTTTGTCCGTCCGAAGCTTCTCCCTATACC CGGTCAAGGGAAGGAACGTCCTCCTCCATAGTGTTTGAGGACTCTGGCTGCGGCAACGCGTCCAGTAAGG AGGAGCCCAGAGGGAACCGGCTGCATGATGGCAACCATTATGTTAATAAGCTAACTGATCTCAAGTGCTC CAGCAGCAGGTCTTCTTCAGAAGCCACCACCTTGTCTACCTCCCCTACCAGGCCAACCACTCTAAGCTTG GATTTCACCAAGAACACTGTGGGCCAGCTCCAGCCCAGCTCCCCCAAGGTGTATCTGTACATTCAGATGC AGCTGTGCAGGAAGGAGAACCTCAAAGACTGGATGAACCGGCGCTGCAGCTTGGAGGACCGGGAGCACGG CGTGTGCCTGCACATCTTCCTGCAGATCGCAGAGGCAGTGGAGTTCCTGCACAGCAAGGGACTCATGCAC AGGGACCTCAAGCCTTCCAACATATTCTTCACAATGGATGATGTGGTCAAGGTTGGGGACTTTGGACTGG TGACTGCTATGGACCAAGATGAAGAAGAGCAGACTGTACTGACTCCAATGCCAGCCTATGCTACGCACAC GGGACAAGTAGGGACCAAGCTATACATGAGCCCAGAGCAGATTCATGGAAACAACTACTCCCATAAAGTG GACATCTTCTCTTTAGGCTTGATTCTGTTTGAACTCCTCTACCCATTCAGCACCCTGATGGAACGAGTCC GGATTTTAACTGATGTCAGAAATCTCAAGTTTCCTCTACTGTTCACTCAGAAATATCCCCAAGAGCATAT GATGGTTCAAGACATGCTCTCTCCATCCCCCACGGAGCGGCCTGAAGCCACAGACATCATTGAAAATGCC ATATTTGAGAACTTGGAGTTTCCCGGGAAAACGGTTCTGAGACAGCGGTCCCGCTCCATGAGTTCATCTG GAACAAAACATTCCAGACAGCCCAGCTGCTCGTACAGCCCACTGCCTGGCAACTAGCCCTCAGCTGCCCT CGAAGGTGGCAGAGCAGGCACCCTGAGGAACATGGCTCTCCACAGCGGTGGACTCAGATTTTATGCTTTG ATCAGTTGGACTCGGGACCAATTTTTCTAAGTCAGACTGGATCACGGGCCTAACCCAGTTTGATCTTAAC TGAACTTCAAGGAAAGGGCTGTGTAAAGGACACATGAACTTGTTGCTTGTCGGTGTCCCAAGACTAGCTG GTCAGCTTAGAACCTTCACTTTTCACCAGGCGGTAGAAGAGATCCTCAAATGGTCTGAACTGGAAATGTC TTTAAAGCACAAAAGTGTAAAAGACCCTCTCACATGGGAACTACATGTTCTAGAAACGTGCTTTCTAGAG ATACAAGGGTGATTTTGGAAGTGGTTGTTATAAAGCTGACTTCATTTTTTTCCCTGGTGAGCCGTGACCC ATCTGCACTAATTTGCAAGGCACATAGCACAAGCTGGGTCGCCATTTATGTCGGTAGTGTCATAGTCTGC AGCAGTGAATAGCGTCATTCTTCAGGTGGTCTAGGGAGCGCGAAGAGCTTTTTTGTACTTTTTACCTCCA ATAATGGGAAAATGAAGCTTTTAGGTATTGGTCAAAAGATCTGATTTGAGAGTTTTGGGTTTTTTTTTTA AGTGCAGTAGGAAATGGATTATCTATTACAACTAACTTCTTCAATTATGGAATTTTTATCCTAGTAGAAT TCTGTCTTAAATGTAATACTACAAGTGGGTACATTCCCCCAAACTGATTATAGATAAGTTTAATCATCTC AACTTGCTAACATGTTTTCATTTTTCCTGTAAATACGTTTATTTTTTATTTATAAAAATTCTGAAATCAA TCCATTTGGGTTGGTGGTGTACAGAACGCACGTAAGTGTGATAACTATTATGACTTCTTTCAAGTCTAAA TGATTTAATAAAAAAATTTTAAATTATAAAAAAAAAAAAAAAAA
• Restriction Sites: AscI-NotI
• ACCN: NM_010121
• ORF Size: 3345 bp
• Insert Size: 3345
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: BC054809, AAH54809
• RefSeq Size: 4524
• RefSeq ORF: 3345
• Locus ID: 13666
• Gene Summary: The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in a similar gene in human are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Sep 2015]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.