Gaa (NM_008064) Mouse Untagged Clone

CAT#: MC203732

Gaa (untagged) - Mouse glucosidase, alpha, acid (Gaa), transcript variant 1, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Gaa
• Synonyms: E430018M07Rik
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC010210
  GCTGCCCGCTGAGCCTGGGGGTCTTCGGCCTGGAGGGTGATTGCGCAGGTGAGCTGGGCGAGCTGGTGAA GGCTGTCTCCGGCCCCAGAGCCTCCGGAGGAGCGGCCTCCTCCAGGCAGGCAGGGCCGACTGTCAGCGAG TTCCTGCTTTGGAGAATCGAGCAGAGACACGCGGCATAGGCCTTCAGAAGTATTCATGCTGCCCCGAACC AACAGGCTTTCACCATGAATATACGGAAGCCCCTCTGTTCGAACTCCGTGGTTGGGGCCTGCACCCTTAT CTCTCTGACTACAGCGGTCATCCTGGGTCATCTCATGCTTCGGGAGTTAATGCTGCTTCCCCAAGACCTT CATGAGTCCTCTTCAGGACTGTGGAAGACGTACCGACCTCACCACCAGGAAGGTTACAAGCCAGGGCCTC TGCACATCCAGGAGCAGACTGAACAGCCCAAAGAAGCACCCACACAGTGTGATGTGCCCCCCAGCAGCCG CTTTGACTGTGCCCCCGACAAAGGCATCTCACAGGAGCAATGCGAGGCCCGCGGCTGCTGCTATGTCCCA GCAGGGCAGGTGCTGAAGGAGCCGCAGATAGGGCAGCCCTGGTGTTTCTTCCCTCCCAGCTACCCAAGCT ACCGTCTAGAGAACCTGAGCTCTACAGAGTCGGGGTACACAGCCACCCTGACCCGTACCAGCCCGACCTT CTTCCCAAAGGATGTGCTGACCTTACAGCTGGAGGTGCTGATGGAGACAGACAGCCGCCTCCACTTCAAG ATCAAAGATCCTGCTAGTAAGCGCTACGAAGTGCCCCTGGAGACCCCACGTGTGCTGAGCCAGGCACCAT CCCCACTTTACAGCGTGGAATTCTCAGAGGAACCCTTTGGAGTGATCGTTCGTAGGAAGCTTGGTGGCCG AGTGTTGCTGAACACAACCGTGGCCCCCCTGTTCTTCGCTGACCAGTTCCTGCAGCTGTCCACTTCCCTG CCCTCCCAGCACATCACAGGCCTGGGGGAACACCTCAGCCCACTCATGCTCAGCACCGACTGGGCTCGTA TCACCCTCTGGAACCGGGACACACCACCCTCGCAAGGTACCAACCTCTACGGGTCACATCCTTTCTACCT GGCACTGGAGGACGGTGGCTTGGCTCACGGTGTCTTCTTGCTAAACAGCAATGCCATGGATGTCATCCTG CAACCCAGCCCAGCCCTAACCTGGAGGTCAACGGGCGGGATCCTGGATGTGTATGTGTTCCTAGGCCCAG AGCCCAAGAGCGTTGTGCAACAATACCTGGATGTTGTGGGATACCCCTTCATGCCTCCATACTGGGGCCT CGGCTTCCACCTCTGCCGCTGGGGCTACTCCTCGACCGCCATTGTCCGCCAGGTAGTGGAGAACATGACC AGGACACACTTCCCGCTGGATGTGCAATGGAATGACCTGGACTACATGGACGCCCGAAGAGACTTCACCT TCAACCAGGACAGCTTTGCCGACTTCCCAGACATGGTGCGGGAGCTGCACCAGGGTGGCCGGCGCTACAT GATGATCGTGGACCCTGCCATCAGCAGCGCAGGCCCTGCTGGGAGTTACAGGCCCTACGACGAGGGTCTG CGGAGGGGTGTGTTCATCACCAACGAGACTGGGCAGCCGCTGATTGGGAAGGTTTGGCCCGGAACCACCG CCTTCCCTGATTTCACCAACCCTGAGACCCTTGACTGGTGGCAGGACATGGTGTCTGAGTTCCACGCCCA GGTGCCCTTCGATGGCATGTGGCTCGACATGAACGAACCGTCCAACTTCGTTAGAGGCTCTCAGCAGGGC TGCCCCAACAATGAACTGGAGAACCCCCCCTATGTGCCCGGGGTGGTTGGCGGGATCTTGCAGGCAGCCA CCATCTGTGCCTCCAGCCACCAATTCCTCTCCACACACTACAACCTCCACAACCTGTACGGCCTCACTGA AGCTATCGCCTCCAGCAGGGCCCTGGTCAAGACTCGGGGAACACGACCCTTTGTGATCTCCCGCTCAACC TTCTCGGGCCACGGCCGGTACGCTGGTCACTGGACAGGGGATGTGCGGAGCTCTTGGGAGCATCTTGCAT ACTCTGTGCCAGACATCCTGCAGTTCAACCTGCTGGGCGTGCCCCTGGTCGGGGCGGACATCTGCGGCTT CATAGGAGACACGTCAGAAGAGCTGTGTGTGCGCTGGACCCAGTTGGGGGCCTTCTACCCCTTCATGCGG AACCACAATGACCTGAATAGCGTGCCTCAGGAGCCGTACAGGTTCAGCGAGACGGCGCAGCAGGCCATGA GGAAGGCCTTCGCCTTACGCTATGCCCTTCTGCCCTACCTGTACACTCTCTTCCACCGCGCCCACGTCAG AGGAGACACGGTGGCCCGGCCCCTCTTCCTGGAGTTCCCTGAGGATCCCAGCACCTGGTCTGTGGACCGC CAGCTCTTGTGGGGGCCGGCCCTGCTCATCACACCTGTGCTTGAGCCTGGGAAAACTGAAGTGACGGGCT ACTTCCCCAAGGGCACGTGGTACAACATGCAGGTGGTGTCAGTGGATTCCCTCGGTACTCTCCCTTCTCC ATCATCGGCTTCATCCTTCAGATCTGCTGTCCAGAGCAAGGGGCAGTGGCTGACACTGGAAGCCCCACTG GATACCATCAACGTGCACCTGAGGGAGGGGTACATCATACCGCTGCAGGGTCCCAGCCTCACAACCACGG AGTCCCGAAAGCAGCCCATGGCTCTGGCTGTGGCATTAACAGCAAGCGGCGAGGCCGATGGGGAGCTGTT CTGGGACGACGGGGAGAGCCTTGCAGTTCTGGAGCGTGGGGCCTACACACTGGTCACCTTCTCAGCCAAG AACAATACCATTGTGAACAAGTTAGTGCGTGTGACCAAGGAGGGAGCTGAGCTACAACTGAGGGAGGTGA CCGTCTTGGGAGTGGCCACAGCTCCTACCCAGGTCCTTTCCAACGGCATCCCTGTCTCCAATTTCACCTA CAGCCCTGACAACAAGAGCCTGGCCATCCCTGTCTCACTGCTGATGGGAGAGCTGTTTCAAATCAGCTGG TCCTAGGAGAGTCCGTCGTTTACAGAGGCCTCCAGGGAGGCAGAGGGAGCTTGAGCTGGCTCTGGCTGGT GGCTCCTGTAAGGACCTGCGTCCTGCTCTCCTGACACATCTTTGAGCTTTTCCCACCGTGTTGCTGCATG CGCCCCTGAAGCTCTGTGTTCTTAGGAGAGTGAGGCTCGCCTCACCTGCCCCACCCCAGCTGTCTGTCCC TCACCTGGCACTAGAGAATGTGGAGCTCGGCGTGGGGACATCGTGTCTGCACCAACATCAGGCTGTGCAG CCACTGCAGCCGCAACCCTGCAGAGACAGAGCTGGTGCCTTCACCAGGTTCCCAAGACTTGAGAAACTTA CTGTGAAGTGTACTTACTTTTAATAAAAAGGATATTGTTTGGAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_008064
• ORF Size: 2862 bp
• Insert Size: 2862
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: BC010210, AAH10210
• RefSeq Size: 3504
• RefSeq ORF: 2862
• Locus ID: 14387
• Gene Summary: This gene encodes a lysosomal acid glucosidase that is involved in the degradation of glycogen. The encoded preproprotein undergoes proteolytic processing to generate a mature enzyme that cleaves alpha-1-4 and alpha-1-6 glycosidic bonds of glycogen, maltose and intermediate oligosaccharides within the lysosome. Mice lacking the encoded protein exhibit symptoms similar to human Pompe syndrome such as accumulation of glycogen in cardiac and skeletal muscle lysosomes resulting in reduced mobility and strength. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Nov 2015]
  Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.