Selenos (NM_024439) Mouse Untagged Clone

CAT#: MC203796

Vimp (untagged) - Mouse histocompatibility 47 (H47), (10ug), (Note: selenocysteine protein, Internal stop codon present. see reference data summary below)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Symbol: Selenos
• Synonyms: 1500011E07Rik; C78786; H-4; H-47; H4; H47; Sels; Seps1; Vimp
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC011091
  CGCAGAGCAGAGAGGAGCAGCGGGCTTGTCGTTGGTGGCGGTGGCGGTGGCCGCCATGGATCGCGATGAG GAACCTCTGTCTCCGAGGCCGGCGCTGGAGACCGAGAGCCTGCGATTCCTGCACGTGACAGTGGGCTCCC TGCTGGCCAGCTATGGCTGGTACATCCTCTTCAGCTGCATCCTACTCTACATTGTCATCCAGAGGCTCTC CCTTCGACTGAGGGCTTTGAGGCAGAGACAGCTGGACCAAGCCGAGACTGTTCTGGAACCTGATGTTGTT GTTAAGCGACAAGAGGCTTTAGCAGCTGCTCGTTTGAGAATGCAGGAAGATCTAAATGCCCAAGTTGAAA AACATAAGGAAAAACTAAGACAGCTTGAAGAAGAAAAAAGAAGACAGAAGATTGAAATGTGGGACAGCAT GCAAGAAGGCAGAAGTTACAAAAGAAATTCAGGAAGGCCTCAGGAAGAAGATGGTCCTGGACCTTCTACT TCATCTGTCATCCCCAAAGGAAAATCTGACAAAAAGCCTTTGCGAGGAGGTGGTTATAACCCTCTGACGG GTGAAGGGGGTGGAACCTGCTCCTGGAGACCTGGACGCAGGGGCCCATCATCTGGTGGATGAAACTAAGA CTCTTGTTAGTGTCGCTCTGACATTAGCAAGGTGAACCTTTAACCCTCAACTCAATTGCCTTACGCACAC TTTCACAGTGACTGGCCAAGGAGAGGTGGGGCTTTTCTCTGTTCTAAACTACTTGTACTTTAAGGGCTTT GGTCAGCATGAGATATAGACATTGCCATTAGGCCACACTCTAGACAAGACAGCCATGGCTTTCATGGCTG CTGGCTAGTTGGTAGGTTGAAGGCTTCTTGCTGTTTAGCAGACTTCATAAAGGAGGCCCAGTGATGATAC TTTGGGGTAGAAGTCCTTGCTGACAGGATGGTCTCTGTGACGGGATGCGTTGAATGATGTCTTCCTTATA AATGGTGAACCCACCAGTGAGGATTACTGATGTTCACAGTTGATGGGGTTTGCTTCTGTATATTTATTTT ATGTACAGAACTTTGTAAAAAAAAAAAGTTAAATACTTAAAAAGTAACATTTTTAGCATCTTTATTAAAC TCAAGGAAATTTCTTTGTGAGCTTGACTTTGTCAGACAGTAAACAGCTTTGTATCAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_024439
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). The expression of this clone is not guaranteed due to the nature of selenoproteins.
• OTI Annotation: This clone encodes a selenoprotein containing the rare amino acid selenocysteine (Sec). Sec is encoded by UGA codon, which normally signals translational termination. Expression of this clone is not guaranteed due to the nature of selenoproteins.

Reference Data

• RefSeq: BC011091, AAH11091
• RefSeq Size: 1219
• Locus ID: 109815
• Gene Summary: This gene encodes a transmembrane protein that is localized in the endoplasmic reticulum (ER). It is involved in the degradation process of misfolded proteins in the ER, and may also have a role in inflammation control. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Two additional phylogenetically conserved stem-loop structures (Stem-loop 1 and Stem-loop 2) in the 3' UTR of this mRNA have been shown to function as modulators of Sec insertion (PMID:23614019). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2017]
  Transcript Variant: This variant (1) represents the predominant transcript and encodes the longer isoform (1).