Cdkn2c (NM_007671) Mouse Untagged Clone

CAT#: MC204135

Cdkn2c (untagged) - Mouse cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) (Cdkn2c), (10ug)


  "NM_007671" in other vectors (4)

Reconstitution Protocol

USD 210.00

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Size
    • 10 ug

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Specifications

Product Data
Type Mouse Untagged Clone
Tag Tag Free
Symbol Cdkn2c
Synonyms C77269; INK4c; p18; p18-INK4c; p18-INK6; p18INK4c
Vector PCMV6-Kan/Neo
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>BC027026
CCCCTCTCCAATGGGCTCACTTTTGCTGAATAATCACGTGTGAATCGAGGGGCGGGCTTTTGGCAGGCCG ACCTTACTAGTATTTACTACCAAGCTCTACTCCAGATTAACCATCCCAGTCCTTCTGTCAGCCTCCGATG CCATCATGCAGCCTGATTAGGAGCAAAGGAAAGGGGAAAAAGAGAAGCAACTAATCGTCTTTTCCCGATC GTCAGGACCCTAAAGAATGGCCGAGCCTTGGGGGAACGAGTTGGCGTCCGCAGCTGCCAGGGGGGACCTA GAGCAACTTACTAGTTTGTTGCAAAATAATGTAAACGTCAACGCTCAAAATGGATTTGGGAGAACTGCGC TGCAGGTTATGAAACTTGGAAATCCGGAGATTGCCAGGAGGCTTCTCCTCAGAGGTGCTAATCCCAATTT GAAAGATGGAACTGGTTTTGCTGTCATTCATGATGCTGCCAGAGCAGGTTTCCTGGACACTGTACAGGCT TTGCTGGAGTTCCAGGCTGATGTTAACATTGAAGATAATGAAGGGAACCTGCCCTTGCACTTGGCTGCCA AAGAAGGCCACCTCCCTGTGGTGGAGTTCCTTATGAAGCACACAGCCTGCAATGTGGGGCATCGGAACCA TAAGGGGGACACCGCCTTCGACTTGGCCAGGTTCTATGGAAGAAATGAGGTCATTAGCCTGATGGAGGCA AATGGGGTTGGGGGAGCCACAAGCCTGCAGTGAATGTGTAGAGGTCTCTCTCACTGACCTCACACTGTCC GTTAGTTGGTTGGCTGTCCGTTTCACTATCACTTATTAAAATATAGGGTTTCCTTTCGCTTTGTTTTCAT ATTTTAAGCAGCCAAATCCTTCAAAACTGCCTAAGTGGAAATCTTACTACAAGTTTATGAAATATTTAAA CTTCTTTTTCACTGTCAAAATTCTGATTTCTAACATGTAATAGCTATTCCTTTTTTTCTGGATATTTTAT CTTTGATTTTTTTTTTCTTTGCTTACCCTTTTTCATTCTCAGTGTCTGACTTGGAGACTTTGTTTTAAAA ATTATTTGTCCTGATGCATCTTTTGCCTAATTAAAACACATTTTTCCAGAAGAGGAAAAAAAAAAAAAA
Restriction Sites RsrII-NotI     
ACCN NM_007671
ORF Size 507 bp
Insert Size 507
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq BC027026, AAH27026
RefSeq Size 1119
RefSeq ORF 507
Locus ID 12580
Gene Summary The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase (cdk) inhibitors, and contains five ankyrin repeats. This protein interacts with both Cdk4 and Cdk6 to inhibit their kinase activities, and prevent their interactions with D-type cyclins, thereby negatively regulating cell division. This gene is differentially expressed in a variety of tissues, and is cell cycle regulated. Deletion of this gene can lead to tumor growth. Maximal expression is observed at the G2/M phase. Alternative splicing and promoter usage results in multiple transript variants. [provided by RefSeq, Aug 2014]
Transcript Variant: This variant (2, also known as p18(S)) differs in the 5' UTR and represents use of an alternate promoter, compared to variant 1. Both variants 1 and 2 encode the same protein.

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