Proc (NM_001042767) Mouse Untagged Clone

CAT#: MC204280

Proc (untagged) - Mouse protein C (Proc), transcript variant 2, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Proc
• Synonyms: PC
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC013896
  CCACGCGTCCGGGATTAACCTGACTCCCAGACTGACATGGCGCTACCTGGACGAAATTGCAGTTTCTCCT TGGCCCACGCCTGTGTCAGCAGCTCCAGGATGTGGCAATTCAGAGTCTTCCTGCTGCTCATGTCCACCTG GGGAATATCTAGCATACCGGCCCATCCTGACCCAGTGTTCTCCAGCAGCGAGCATGCCCACCAGGTGCTT CGGGTCAGACGTGCCAACAGCTTCCTGGAAGAGATGCGGCCAGGCAGCCTGGAACGGGAGTGTATGGAGG AGATCTGTGACTTCGAGGAGGCCCAGGAGATTTTCCAAAATGTGGAAGACACACTGGCCTTCTGGATCAA GTACTTTGACGGTGACCAGTGCTCGGCTCCACCCTTGGACCACCAGTGCGACAGCCCATGCTGCGGGCAT GGCACTTGCATCGACGGCATAGGCAGCTTCAGCTGCAGCTGCGATAAGGGCTGGGAGGGCAAGTTCTGTC AGCAGGAGTTGCGCTTCCAGGACTGTCGGGTGAACAATGGCGGCTGCTTGCACTACTGCCTGGAGGAGAG CAATGGGCGGCGCTGCGCTTGTGCCCCGGGCTATGAGCTGGCAGACGACCACATGCGCTGCAAGTCCACT GTGAATTTTCCATGTGGGAAACTGGGGAGGTGGATAGAGAAGAAACGCAAGATCCTCAAACGAGACACAG ACTTAGAAGATGAACTGGAACCAGATCCAAGGATAGTCAACGGAACGCTGACGAAGCAGGGTGACAGTCC TTGGCAGGCAATCCTTCTGGACTCCAAGAAGAAGCTGGCCTGCGGAGGGGTGCTCATCCACACTTCCTGG GTGCTGACGGCAGCCCACTGCGTGGAGGGCACCAAGAAGCTTACCGTGAGGCTTGGTGAGTATGATCTGC GACGCAGGGACCACTGGGAGCTGGACCTGGACATCAAGGAGATCCTCGTCCACCCTAACTACACCCGGAG CAGCAGTGACAACGACATTGCTCTGCTCCGCCTAGCCCAGCCAGCCACTCTCTCCAAAACCATAGTGCCC ATCTGCCTGCCGAACAATGGGCTGGCGCAGGAGCTCACTCAGGCTGGCCAGGAGACAGTGGTGACAGGCT GGGGCTATCAAAGCGACAGAATCAAGGATGGCAGAAGGAACCGCACCTTCATCCTCACCTTCATCCGCAT CCCTTTGGTTGCTCGAAATGAGTGCGTGGAGGTCATGAAGAATGTGGTCTCGGAGAACATGCTGTGTGCA GGCATCATTGGGGACACGAGAGACGCCTGTGATGGTGACAGTGGGGGGCCCATGGTGGTCTTCTTTCGGG GTACCTGGTTCCTGGTGGGCCTGGTGAGCTGGGGTGAGGGCTGTGGGCACACCAACAACTATGGCATCTA CACCAAAGTGGGAAGCTACCTCAAATGGATTCACAGTTACATTGGGGAAAAGGGTGTCTCCCTTAAGAGC CAGAAGCTATAGCACCCCTCCCTGCTCACCTCTGGACCCTAGAAGTCACTCTTGGAGTAAGGCTGGGCTA GTGAGTACCAAGACAGAGGACATTAAAGGAGCATGCAACAAACATAAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_001042767
• ORF Size: 1383 bp
• Insert Size: 1383
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: BC013896, AAH13896
• RefSeq Size: 1603
• RefSeq ORF: 1383
• Locus ID: 19123
• Gene Summary: This gene encodes the vitamin K-dependent protein C, which plays a vital role in the anticoagulation pathway. The encoded protein undergoes proteolytic processing including activation by thrombin-thrombomodulin complex to form the anticoagulant serine protease that degrades activated coagulation factors. A complete lack of the encoded protein in mice results in severe perinatal consumptive coagulopathy in the brain and liver, resulting in death within 24 hours after birth. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate the mature protein. [provided by RefSeq, Sep 2015]
  Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and uses an in-frame downstream start codon, compared to variant 1. The encoded isoform (2) is shorter at the N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.