Sphk2 (NM_020011) Mouse Untagged Clone

CAT#: MC204704

Sphk2 (untagged) - Mouse sphingosine kinase 2 (Sphk2), transcript variant 2, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Sphk2
• Synonyms: C76851
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC053737
  CCAGAACCAAAGAGAAGTCAGCCTGAGGAAAGGGCTGGGACCCGGAGCCTCTCTGGCCTTTCCCCGTCCC TGCTCTAACACTCTCCAGGGGTAAAGGGACCGGAGAATCAGAGACATGATCGGAGCTTGCTGGACGAGTC GCGTGGTGACTCTCTGGCCGCACGCCGACCGCTTCTCGGTGGCTCGCGGAGGACCCGGTGGGCTGTGTGT CGGAGCCTCCGAAGTAGCTGGGATCACCGTCTTTCAACACTTGGCCTGGCTCTGCCATTTAAAGTTGTGA TCTTGGAGGCTGGTCCAGGAGCTGACCACAAGCCAAGAGCCTAGGAGTGCTTGGGACTGAACCAGGGTCA TGGCCCCACCACCACTACTGCCAGTGGCTGCCAGCACTCCAATCCTGCACGGCGAGTTTGGTTCCTACCC GGCCAACGGCCCACGGTTTGCCCTCACCCTCACAACACAAGCCCTACACATACAGCGACTACGCCCAAAG CCAGAAGCCCGGCCCCGAGATGGTCTAGTCTCTCTGGATGAGGTCTCGGGCTGTGGCACCCTGCAGAGCC GTAGCCCCGAGGACACTGCAGCCTACTTCTGCATCTACACCTACCCACGTGGCCGTCGAGGGGGCCGGCG CAGAGCTACGCGGACCTTCCGGGCGGATGGGGCCACCACTTATGAGGAGAATCGTGCAGAGGCCCAGCGC TGGGCCACTGCCCTCACGTGTCTCCTCCGAGGAGTGCCTCTGTCAGGGGACCAGGAAATCACCCCTGAAT TGCTGCCCCGGAAGCCCAGGCTGCTCATATTGGTCAATCCCTTTGGGGGGCGGGGCCTGGCCTGGCAGCG CTGTATGGACCACGTGGTGCCAATGATCTCTGAAGCTGGGCTGTCCTTCAACCTCATACAGACAGAACGA CAGAACCATGCCCGTGAGCTGGTGCAGGGGTTAAGCCTGAGTGAGTGGGAAGGCATTGTCACTGTGTCTG GAGACGGGCTGCTTTACGAGGTGCTGAATGGGCTCCTTGATCGGCCAGACTGGGAGGATGCCGTGCGGAT GCCCATTGGTGTCCTCCCCTGTGGATCGGGCAATGCGCTAGCTGGGGCGGTGAACCATCATGGCGGGTTT GAGCAGGTTGTCGGTGTTGACCTGTTGCTCAACTGCTCGCTTCTTCTCTGCCGTGGTGGCAGCCATCCTC TGGACCTGCTCTCTGTGACGCTAGCCTCGGGATCCCGCTGTTTTTCCTTCCTGTCAGTGGCCTGGGGATT CTTGTCAGATGTGGACATTCACAGTGAGCGCTTCAGGGCCCTGGGCAGCGCTCGATTCACACTGGGTGCA GTGCTAGGCCTGGCCTCGTTGCATACCTACCGTGGACGCCTCTCCTACCTCCCCGCTACCACAGAACCAG CCTTGCCCATCCCAGGCCACAGTCTGCCTCGAGCCAAGTCAGAACTAGTCTTGGCTCCAGCCCCAGCCCC CGCCGCCACCCACTCGCCTCTACATCGATCTGTGTCTGACCTGCCTCTGCCCCTTCCCCAGCCTGCCTTG GTCTCCCCTGGCTCCCCTGAGCCCCTGCCTGACCTGTCCCTCAATGGTGGTGGTCCAGAGCTGACTGGAG ACTGGGGAGGAGCTGGGGATGCACCTCTGTCCCCAGACCCACTGCTGCCTTCATCCCCCAACGCTCTCAA AACAGCTCAGCTTTCACCCATCGCTGAAGGGCCCCCAGAAATGCCAGCATCTTCGGGGTTCCTGCCTCCC ACCCACAGTGCCCCAGAAGCCTCTACCTGGGGCCCAGTGGACCACCTCCTCCCTCCCCTGGGCTCTCCAC TGCCCCAAGACTGGGTGACAATAGAGGGGGAGTTTGTACTCATGTTGGGCATCTTGCCGAGCCACCTCTG CGCAGACCTGATGGCAGCCCCACATGCACGCTTTGATGATGGCGTTGTGCACCTGTGTTGGGTGCGGAGC GGCATCTCACGGGCTGCACTTCTACGCATTTTGCTGGCCATGGAGCATGGAAACCACTTCAGCCTGGGCT GCCCCCATCTGGGCTATGCTGCAGCACGTGCCTTCCGCCTTGAACCACTCACGCCTCGTGGCCTGCTCAC TGTAGATGGGGAGTTAGTGGAGTATGGGCCAATACAGGCGCAGGTGCACCCAGGTCTCGCCACGCTGCTC ACTGGGCCTGCAGGTCAAAAGCCGCAAGCCTGAACGAGCCTAAAAGCATGGCGAGTTGGTGGAACCAGCG CCCCATAGGCTAAGATCTATCATTTACAGGTAGAAGTGGGGCCCGCACTCAGAACTGTGAGGAGGGTGGA GAGTGGTCCTGACCCTCAGTTCCCAGAGGACCTAGAGGCTCGAGGGTGGGGCCTGCCTTTCTTGATGTCC AATGATGGGGCCTGGAATGTATGAGCTAGCAAGGCTTCTTCAGCTTATTGACCAGCCAGGGTTTCTTCTT GCCTACTCCGGTGCCTCTACTTGACTGGCCAATCAGCCCTTGAGGGGCAGGTTCCCCCAGGTGGTCCCCA GATTTGCACTAATGTTCCTCCCCTGGCCAGTTAGGGATGGGATGTTCTGTGTCTTGTGTGTCCCTCTCCC TAGTCTAAAAAGCAATTGAAAAGGTCTATGCAATAAAGGTTGTTGCTTCCCTCTAGGCCTTCACCCCTTC CACCCGAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_020011
• ORF Size: 1854 bp
• Insert Size: 1854
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: BC053737, AAH53737
• RefSeq Size: 2691
• RefSeq ORF: 1854
• Locus ID: 56632
• Gene Summary: This gene encodes a kinase that phosphorylates sphingosine into sphingosine-1-phosphate, which is involved in cell differentiation, motility, and apoptosis. The encoded protein plays a role in maintaining cellular levels of sphingosine-1-phosphate. The gene product also enhances apoptosis in different cell types and suppresses cellular proliferation. In mast cells, the encoded protein is necessary for influx of calcium, protein kinase C activation, and cytokine production and degranulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
  Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.