Srebf1 (NM_011480) Mouse Untagged Clone

CAT#: MC205184

Srebf1 (untagged) - Mouse sterol regulatory element binding transcription factor 1 (Srebf1), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Srebf1
• Synonyms: ADD1; bHLHd1; SREBP1
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC056922
  CCTTAACGTGGGCCTAGTCCGAAGCCGGGTGGGCGCCGGCGCCATGGACGAGCTGGCCTTCGGTGAGGCG GCTCTGGAACAGACACTGGCCGAGATGTGCGAACTGGACACAGCGGTTTTGAACGACATCGAAGACATGC TCCAGCTCATCAACAACCAAGACAGTGACTTCCCGGGCCTGTTTGACGCCCCCTATGCTGGGGGTGAGAC AGGGGACACAGGCCCCAGCAGCCCAGGTGCCAACTCTCCTGAGAGCTTCTCTTCTGCTTCTCTGGCCTCC TCTCTGGAAGCCTTCCTGGGAGGACCCAAGGTGACACCTGCACCCTTGTCCCCTCCACCATCGGCACCCG CTGCTTTAAAGATGTACCCGTCCGTGTCCCCCTTTTCCCCTGGGCCTGGGATCAAAGAGGAGCCAGTGCC ACTCACCATCCTACAGCCTGCAGCGCCACAGCCGTCACCGGGGACCCTCCTGCCTCCGAGCTTCCCCGCA CCACCCGTACAGCTCAGCCCTGCGCCCGTGCTGGGTTACTCGAGCCTGCCTTCAGGCTTCTCAGGGACCC TTCCAGGAAACACTCAGCAGCCACCATCTAGCCTGCCGCTGGCCCCTGCACCAGGAGTCTTGCCCACCCC TGCCCTGCACACCCAGGTCCAAAGCTTGGCCTCCCAGCAGCCGCTGCCAGCCTCAGCAGCCCCTAGAACA AACACTGTGACCTCACAGGTCCAGCAGGTCCCAGTTGTATTGCAGCCACACTTCATCAAGGCAGACTCAC TGCTGCTGACAGCTGTGAAGACAGATGCAGGAGCCACCGTGAAGACTGCAGGCATCAGCACCCTGGCTCC TGGCACAGCCGTGCAGGCAGGTCCCCTGCAGACCCTGGTGAGTGGAGGGACCATCTTGGCCACAGTACCT TTGGTTGTGGACACAGACAAACTGCCCATCCACCGACTCGCAGCTGGCAGCAAGGCCCTAGGCTCAGCTC AGAGCCGTGGTGAGAAGCGCACAGCCCACAATGCCATTGAGAAGCGCTACCGGTCTTCTATCAATGACAA GATTGTGGAGCTCAAAGACCTGGTGGTGGGCACTGAAGCAAAGCTGAATAAATCTGCTGTCTTGCGCAAG GCCATCGACTACATCCGCTTCTTGCAGCACAGCAACCAGAAGCTCAAGCAGGAGAACCTGACCCTACGAA GTGCACACAAAAGCAAATCACTGAAGGACCTGGTGTCAGCTTGTGGCAGTGGAGGAGGCACAGATGTGTC TATGGAGGGCATGAAACCCGAAGTGGTGGAGACGCTTACCCCTCCACCCTCAGACGCCGGCTCACCCTCC CAGAGTAGCCCCTTGTCTTTTGGCAGCAGAGCTAGCAGCAGTGGTGGTAGTGACTCTGAGCCCGACAGTC CAGCCTTTGAGGATAGCCAGGTCAAAGCCCAGCGGCTGCCTTCACACAGCCGAGGCATGCTGGACCGCTC CCGCCTGGCCCTGTGTGTACTGGCCTTTCTGTGTCTGACCTGCAATCCTTTGGCCTCGCTTTTCGGCTGG GGCATTCTCACTCCCTCTGATGCTACGGGTACACACCGTAGTTCTGGGCGCAGCATGCTGGAGGCAGAGA GCAGAGATGGCTCTAATTGGACCCAGTGGTTGCTGCCACCCCTAGTCTGGCTGGCCAATGGACTACTAGT GTTGGCCTGCTTGGCTCTTCTCTTTGTCTATGGGGAACCTGTGACTAGGCCACACTCTGGCCCGGCTGTA CACTTCTGGAGACATCGCAAACAAGCTGACCTGGATTTGGCCCGGGGAGATTTCCCCCAGGCTGCTCAAC AGCTGTGGCTGGCCCTGCAAGCGCTGGGCCGGCCCCTGCCCACCTCAAACCTGGATCTGGCCTGCAGTCT GCTTTGGAACCTCATCCGCCACCTGCTCCAGCGTCTCTGGGTGGGCCGCTGGCTGGCAGGCCAGGCCGGG GGCCTGCTGAGGGACCGTGGGCTGAGGAAGGATGCCCGTGCCAGTGCCCGGGATGCGGCTGTTGTCTACC ATAAGCTGCACCAGCTGCATGCCATGGGCAAGTACACAGGAGGACATCTTGCTGCTTCTAACCTGGCACT AAGTGCCCTCAACCTGGCTGAGTGCGCAGGAGATGCTATCTCCATGGCAACACTGGCAGAGATCTATGTG GCAGCGGCCCTGAGGGTCAAAACCAGCCTCCCAAGAGCCCTGCACTTCTTGACACGTTTCTTCCTGAGCA GCGCCCGCCAGGCCTGCCTAGCACAGAGCGGCTCGGTGCCTCTTGCCATGCAGTGGCTCTGCCACCCTGT AGGTCACCGTTTCTTTGTGGACGGGGACTGGGCCGTGCACGGTGCCCCCCCGGAGAGCCTGTACAGCGTG GCTGGGAACCCAGTGGATCCGCTGGCCCAGGTGACCCGGCTATTCCGTGAACATCTCCTAGAGCGAGCGT TGAACTGTATTGCTCAGCCCAGCCCAGGGGCAGCTGACGGAGACAGGGAGTTCTCAGATGCCCTTGGATA TCTGCAGTTGCTAAATAGCTGTTCTGATGCTGCCGGGGCTCCTGCTTGCAGTTTCTCTGTCAGCTCCAGC ATGGCTGCCACCACTGGCCCAGACCCAGTGGCCAAGTGGTGGGCCTCACTGACAGCTGTGGTGATCCACT GGCTGAGGCGGGATGAAGAGGCAGCTGAGCGCTTGTACCCACTGGTAGAGCATATCCCCCAGGTGCTGCA GGACACTGAGAGACCCCTGCCCAGGGCAGCTCTGTACTCCTTCAAGGCTGCCCGGGCTCTGCTGGACCAC AGAAAGGTGGAATCTAGCCCAGCCAGCCTGGCCATCTGTGAGAAGGCCAGTGGGTACCTGCGGGACAGCT TAGCCTCTACACCAACTGGCAGTTCCATTGACAAGGCCATGCAGCTGCTCCTGTGTGATCTACTTCTTGT GGCCCGTACCAGTCTGTGGCAGCGGCAGCAGTCACCAGCTTCAGTCCAGGTAGCTCACGGTACCAGCAAT GGACCCCAGGCCTCTGCTCTGGAGCTGCGTGGTTTCCAACATGACCTGAGCAGCCTGCGGCGGTTGGCAC AGAGCTTCCGGCCTGCTATGAGGAGGGTATTCCTACATGAGGCCACAGCTCGGCTGATGGCAGGAGCAAG TCCTGCCCGGACACACCAGCTCCTGGATCGCAGTCTGAGGAGGAGGGCAGGTTCCAGTGGCAAAGGAGGC ACTACAGCTGAGCTGGAGCCACGGCCCACATGGCGGGAGCACACCGAGGCCCTGCTGTTGGCATCCTGCT ATCTGCCCCCTGCCTTCCTGTCGGCTCCTGGGCAGCGAATGAGCATGCTGGCCGAGGCGGCACGCACCGT AGAGAAGCTTGGCGATCACCGGCTACTGCTGGACTGCCAGCAGATGCTCCTGCGCCTGGGCGGCGGAACC ACCGTCACTTCCAGCTAGACCCCAAAGCTTTCCCTTGAGGACCTTTGTCATTGGCTGTGGTCTTCCAGAG GGTGAGCCTGACAAGCAATCAGGACCATGCCGACCTCTAGTGGCAGATCTGGAAATTGCAGAGGCTGCAC TGGCCCGATGGCACCCTCTTGCTCTGTAGGCACCTTAGTGGCTTTTCCCTAGCTGAGGCTCACCCTGGGA GACCTGTACATAGTGTAGATCCGGCTGGGCCTGGCTCCAGGGCAGGCCCATGTACTACTTTGACTTTTGC AAACTTTATTTTCATAGGTTGAGAAATTTTGTACAGAATATTAAAAAATGAAATTATTTATAACTTCAGT TTTGTTTATCTGGGTAGGCAGATGTCTGCCTCAGCTGATTGCTATCTTTCCTGGCTTGTCCTTTGGGAAG CCGGACTTCCCATCTGTTGTAAGGTGTATTTGCTGGCTTGGTGATGCTATGTTGAGCCACCTTGGCCCTC TGATCTCATGGCTCATAACCCTTGAGGGGCCTTGATGGTCTCAGTTGTTCCTTTGCCTTCCAGCCCTCCA CCAGGTAATAACCCCGTATATCCAGAAACACACACAGTTCCCTAGTCATCTCTGTGCACCAGCATAGGCG AAGGATCAGGGCCCATTAGTGAGTAGACTGGGAACCCTGTTTGTGTCCCCCGGCCCCTTCCCTCTACTCC CAACCCCTTAGGGAATCTGGTCGGCATCCACAGGCCGCACACTTCCAAAACAATCGTGGTATCTTTATTG ACTTTTTTTTTTCTGAATGCAATGACTGTTTTTTTTTTTTTTAACTCTTAAGGAAAATAAACATCTTTTA GAAACAGCTCGATACAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: AscI-NotI
• ACCN: NM_011480
• ORF Size: 3405 bp
• Insert Size: 3405
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: BC056922, AAH56922
• RefSeq Size: 4306
• RefSeq ORF: 3405
• Locus ID: 20787
• Gene Summary: This gene encodes a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols inhibit the cleavage of the precursor, and the mature nuclear form is rapidly catabolized, thereby reducing transcription. The protein is a member of the basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor family. Alternatively spliced transcript variants have been characterized for this gene. [provided by RefSeq, Nov 2017]
  Transcript Variant: This variant (1, also known as SREBP-1a) represents the longest transcript and encodes the longest isoform (a).