Plat (BC061508) Mouse Untagged Clone
CAT#: MC206405
Plat (untagged) - Mouse plasminogen activator, tissue (cDNA clone MGC:70311 IMAGE:5352018), (10ug)
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Specifications
Product Data | |
Type | Mouse Untagged Clone |
Tag | Tag Free |
Symbol | Plat |
Synonyms | tPA, t-PA, MGC18508 |
Vector | PCMV6-Kan/Neo |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>BC061508
AGGAACTCAAGAGCTCAGCGTCAAGGAGAGGCCCCTGCAAGAGTGGGAAAGAAGCAAGCACTCTCGGGAC ACAGAAGAAACGGGGAGCAAAATGAAGAGAGAGCTGCTGTGTGTACTGCTGCTTTGTGGACTGGCTTTCC CATTGCCTGACCAGGGAATACATGGGAGGTTCAGAAGAGGAGCCCGGTCCTACAGAGCGACCTGCAGAGA TGAGCCAACGCAGACAACTTACCAACAGCACCAGTCGTGGCTCCGACCCATGCTCAGAAGCAGCCGGGTG GAATATTGCCGGTGCAACAGCGGCCTGGTACAATGCCACTCAGTGCCTGTCCGAAGTTGCAGCGAACCAA GATGCTTCAATGGGGGGACGTGTCAGCAGGCCCTGTATTTCTCTGACTTTGTCTGCCAGTGCCCTGATGG ATTTGTAGGGAAACGCTGTGACATAGATACCAGAGCAACATGCTTTGAGGAGCAGGGCATCACCTACAGA GGCACGTGGAGCACAGCAGAAAGTGGGGCTGAGTGCATCAACTGGAATAGCAGTGTTCTGTCGCTGAAGC CCTACAATGCAAGGAGGCCAAATGCCATCAAGCTGGGCCTTGGGAATCACAATTACTGCAGAAACCCAGA CCGAGACTTGAAGCCCTGGTGCTATGTCTTTAAGGCAGGGAAGTATACCACGGAGTTCTGTAGCACACCA GCTTGCCCTAAGGGAAAAAGCGAGGACTGCTATGTTGGGAAAGGTGTGACTTACCGTGGCACCCACAGCC TCACCACATCCCAGGCCTCCTGCCTCCCCTGGAATTCCATAGTCCTCATGGGCAAGAGTTACACAGCGTG GAGGACCAACTCCCAGGCACTCGGCCTGGGCAGACACAATTATTGTCGGAATCCAGATGGTGATGCCAGA CCTTGGTGCCATGTGATGAAGGACCGAAAGCTGACGTGGGAATACTGTGACATGTCCCCATGCTCCACCT GTGGCCTGAGGCAGTACAAACGGCCTCAGTTTAGAATTAAAGGAGGACTCTACACAGACATCACCTCACA CCCTTGGCAGGCTGCCATCTTTGTCAAGAACAAGAGGTCTCCTGGAGAGAGATTCCTTTGTGGAGGGGTG CTGATCAGTTCCTGCTGGGTGCTGTCAGCTGCCCACTGCTTTCTAGAGAGGTTCCCCCCCAATCATCTTA AAGTGGTCTTGGGCAGAACATACAGGGTGGTCCCCGGAGAGGAAGAACAGACATTTGAGATTGAAAAATA CATAGTCCATGAGGAATTTGATGACGATACTTATGACAACGACATCGCATTACTGCAGCTGAGGTCACAG TCCAAGCAATGTGCCCAAGAGAGCAGCTCTGTTGGCACTGCCTGCCTCCCTGACCCCAACCTGCAGCTCC CTGACTGGACAGAGTGTGAGCTTTCTGGCTACGGCAAGCATGAGGCATCGTCTCCATTCTTCTCTGACCG GCTGAAGGAGGCTCACGTCAGACTGTACCCGTCCAGCCGCTGCACCTCACAGCATCTGTTTAATAAAACC GTCACGAACAACATGCTGTGCGCTGGAGACACCCGGAGCGGAGGCAACCAAGACCTCCACGATGCATGCC AGGGTGACTCGGGAGGCCCTCTGGTGTGCATGATCAATAAACAGATGACATTGACTGGCATTATCAGCTG GGGCCTCGGCTGTGGGCAGAAGGATGTGCCTGGGGTCTACACAAAGGTTACGAATTACCTAGACTGGATT CACGACAACATGAAGCAATGACAAAGAAAGCCCAGCTCCTTCAATCCAGAGGAGGACCTGCCTTCCTCTT CCTCTTCTACAGAAGATGCGCCTAAAAGGCCAAGCATTCTTTACACCATCATCTTCGTGAGCTGCCACTC GGGAGAGGGGAGGGGGGTCTTTGGGAGCAGATGTAGCATTTACCTGTGACAGGTACTTCACAACTTGTAA GTTTTAAGGATGAAGGTCTGGCTTTAGAATAAATCCTGTCAGATGAGATGACAGGGAGATGCCAACCTTC CTATAACTCTAGGATTTTAAAAAGAGAGGTAGACCAAAGTCTGCCCTCCTGGTCCACTATGTTGTACACT GAACCACAAGATCATGTCTCAACAGCAAAAAAATACAACTTGATCTTTCAGGAGTGAAAGTTTGCACTGG GGACAAGAATGTGTTTTTATAGTTACACAGGGGGCCCCACAGGGCCTCCACGAGAAGGAAGGGGTATCTG GCCGAATCACAGCACCATAAAATCCTTGAGATCATGCACTCCCCATCCCTCCACACTCCTCAACTCTTGG GACATATCCCTTTGTATACAGTGTAAATGTCTTTTTCTTTATAAACTCTATAGATGGTTGGGAGAACTGT ATGATTTTAATAATTGATGAATAACACTAGTATATTTATATTTTAATCTATTTTAGTTTTTACTTTGTTA CTATAACTTTGTATTATACTGTACTTAAATAATAAATTCAGAGGTATTTTTCACAAAAAAAAAAAAAAAA |
Restriction Sites | RsrII-NotI |
ACCN | BC061508 |
ORF Size | 1680 bp |
Insert Size | 1680 |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Reference Data | |
RefSeq | BC061508, AAH61508 |
RefSeq Size | 2520 |
RefSeq ORF | 1680 |
Locus ID | 18791 |
Gene Summary | This gene encodes a key enzyme of the fibrinolytic pathway. The encoded protein undergoes proteolytic processing by plasmin to generate a heterodimeric serine protease that cleaves the proenzyme plasminogen to produce plasmin, a protease that is required to break down fibrin clots. Additionally, the encoded protein is involved in other biological processes such as synaptic plasticity, cell migration and tissue remodeling. Mice lacking the encoded protein display a reduction in long-term potentiation in hippocampus and conversely, transgenic mice overexpressing the encoded protein have increased and prolonged long-term potentiation. [provided by RefSeq, Jul 2015] |
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