Cldn2 (BC015252) Mouse Untagged Clone

CAT#: MC206508

Cldn2 (untagged) - Mouse claudin 2 (cDNA clone MGC:18348 IMAGE:4223446), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Cldn2
• Synonyms: AL022813
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC015252
  GAAAGAAGTCAGCTTGCCAGAGACACTGTGAAATAAGGGATTAGAGGCTCGGATCCAAGAAGCAAGAGCA GCAGCCAAACGACAAGCAAACAGGCTCCGAAGATACTTCTACTGAGAGGTCTGCCATGGCCTCCCTTGGC GTTCAACTGGTGGGCTACATCCTAGGCCTTTTGGGGCTGTTAGGCACATCCATTGCCATGCTGCTTCCCA ACTGGCGAACGAGTTCCTATGTTGGTGCCAGCATTGTGACGGCGGTTGGCTTTTCCAAGGGCCTCTGGAT GGAGTGTGCGACACACAGCACAGGCATCACCCAGTGCGATATCTACAGTACCCTTTTAGGACTTCCTGCT GACATCCAGGCTGCCCAGGCCATGATGGTGACGTCCAGTGCAATGTCCTCGCTGGCTTGTATTATCTCTG TGGTGGGCATGAGATGCACCGTGTTCTGCCAGGATTCTCGAGCTAAGGACAGAGTGGCTGTAGTGGGTGG AGTCTTTTTCATCCTTGGTGGCATCCTGGGCTTTATCCCAGTTGCTTGGAATCTTCATGGCATCCTTCGG GACTTCTACTCGCCGCTGGTTCCTGACAGCATGAAATTTGAGATTGGAGAGGCTCTGTACTTGGGCATCA TCTCAGCCCTGTTTTCTTTGGTAGCCGGAGTCATCCTTTGCTTTTCCTGCTCGCCCCAGGGCAATCGTAC CAACTACTATGATGGCTACCAGGCCCAGCCTCTTGCCACTAGGAGCTCTCCAAGATCTGCTCAACAGCCC AAAGCCAAGAGTGAGTTCAACTCATACAGCCTGACTGGGTATGTGTGAAGAACCAGGGGCCAGAGCTGGG GGTAGGGTGGGGTAGTGGCTGGGACTATATATATAAAAAAAAGCAGTGGACAATGCCCCCAGGGTCACAA GCAAAGGACATTGCCACTGAATCATGTGTAAGGTGCTGCTGAGGGTAGAATGACTTTGGCCATTGGATGG AGTGAAGGCAGAGATGAGAAGAGGGGTGTCAGCATGTAGATGGCATTGCCAAGGACGCTTGCCAAGCTAG CTTTTCTATTTCCCTCACCTGACCTCACTAAAGTACCTCCTGTGCTTTGAATGCTCAACCCAAAAGCCCA AATCCCATCTCTGCCACTTTAGGCTATGCCCAGAGGCTCTCTTCTGCCCTTTGGTTTACTTGGAGATCTG TCCCCAAACCAATCATATCCTGTTGACTAATCACCTGTGATCAAAAGACCCTCTCCCTCTGGCTGAGGTT GGCTCTTAACTCAATTACTAAGGGACAGAGAGAAGAAAGAGTGGTGGCTTCTGTGAGGACATTTCTAGCT CCCTTCTCAAATCTCCAGCCAAAGAAATGGATTAGTCAGTAATGGGCCCTGAAGCTTCTCTTCCAGTTTT GCTATGAATGCAGTATGTCCAGACTGCATTGTGAATGAACTGAAGGAAAGCTATCTCATGGCATCCAGCA GAATACAGCTGGGTGCAGGATGGGAGGCAACCTGGGATCTAAAGAAACAAAACAAACAGCAAAACCCGAC AGAATCCCTTCTCAGGCCATCTCCTATAATTCCCGTACATTTGTGGGTCAGGGATGGAAGCACTGCTAAG GAAAGCACAAGAAGCCAAGGGAAAGCACATGGCTGCTGCCCTCTGACTCCACAGAGGAATTGCCCAGAAG CCAAGGTGAACACGGACCACTGAAAGCTCTGCCTCCCACTGGGGTGTCTGACCCAGCTTCCTGCTAAACC ACAAGACTTGGAGCCCTAGACAAGGGTTTCCTTAAGGACAATAAACCAGTTTTTCTAGAACTGCCCTTTG ACATGCGAGTTGCAGAAGGCTTAAAAAAAATACTACCCTTTAGCCCTGACCGAGAAAGAATAAGGGCTTG GGTATCAAAGAACCGGACAGAGATGTGTGGTAGCTGTTATGTGTGCTCCTACTGTTTCAGAGAGGCAGCC CTACCAGATACTTTAGACTTGATGGAAGACCAACCCATCAGGGTCTATGTCTCAGCACTACAGAGCCTCT GAAAGACCACAGCACCAGAGAGGTCCTTTGTCACTTTTCACACTTGAGTCATCGCCCATCAGAAGATATT CTCACAGGTATGCAAAGTCTCCAGTGTGGAACATCTGTGACCAAGGTGTTGTGTTCATGACCTGAGCAAT TGGTGAACTTCTGCCTGGGATTGTGCTTGAGGTGGGAGAACGGAGACTGGTTCCCTGTCCAACAGTTTTA TTTCCACGGTCTTAAAATGCTCCATTTCTTCTGTGGTAGATGGGGGTCATAAACCAGAGACATTTCCCCA CCACCAGCAGCTTAATATCACCAGCTTCAGAAGATCCCCAGCGCACCTCATCAAAACTTCAGCACCGGCA AGAGAGGCCCATATGTGAGGTTTCCCTTAACATGCCTTTCCTATTTCCACCATATTACTTGTGTTCAAGC TGATATGCTGACCTGGAAGCCATTTCCTTTTAACTAAGTCATCCCCATGCTTGGAGAACTTGCTCATTGA GCCTTCTCTGACCACTCCTTCCTGTTCTTTCCTTTCCCTCCTCCAACTCCCAATATATAAATTGCCTAAT CCTCATCATTCATAATTTTGATTGATAGTTTATAGTTCTTGTATGTGCATTTGTGTGTGACTCTATCCGT CTGTCTGTCTGTGTGATCTCAAAAGTTCACTGTAAGTACTTGGAGGGCAATTGCTATATCTTAGACCTGT CCATATGTATACCCAAGACTGTAACAGTGCTGGGCACACACAAGGTGATCAATAAACGGATGTTGATTGA GTAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: EcoRI-NotI
• ACCN: BC015252
• ORF Size: 693 bp
• Insert Size: 693
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: BC015252, AAH15252
• RefSeq Size: 2828
• RefSeq ORF: 693
• Locus ID: 12738
• Gene Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The knockout mice lacking this gene display normal appearance, activity, growth and behavior, but are defective in the leaky and cation-selective paracellular permeability properties of renal proximal tubules. The proteins encoded by this gene and another family member Cldn12 are also critical for vitamin D-dependent Ca2+ absorption between enterocytes. [provided by RefSeq, Aug 2010]