Acvr1c (NM_001033369) Mouse Untagged Clone

CAT#: MC214283

Acvr1c (untagged) - Mouse activin A receptor, type IC (Acvr1c), transcript variant 2, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Acvr1c
• Synonyms: ACTR-IC; ACVRLK7; Alk-7; ALK7; C230097P10
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC214283 representing NM_001033369
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCTAACCAACGGGAAAGAGCAGGTGATCAAATCGTGTGTGTCCCTCCCGGAACTAAATGCTCAGGTCT
  TCTGTCACAGTTCCAACAACGTGACCAAAACCGAATGTTGCTTCACAGACTTCTGCAACAATATCACACT
  GCACCTTCCCACAGGTCTGCCTCTCTTGGTTCAAAGAACAATCGCAAGGACAATTGTACTTCAAGAAATC
  GTAGGAAAAGGTCGGTTTGGGGAAGTGTGGCACGGAAGATGGTGTGGAGAAGATGTGGCTGTGAAAATAT
  TCTCCTCCAGGGATGAGAGATCTTGGTTCCGTGAGGCGGAAATTTATCAGACGGTGATGCTGAGACACGA
  GAACATCCTCGGTTTCATCGCAGCTGACAACAAAGATAATGGAACTTGGACACAACTCTGGCTTGTGTCA
  GAGTATCACGAGCAGGGCTCCTTGTATGACTATTTGAACAGAAACATAGTGACTGTGGCTGGAATGGTCA
  AGCTGGCGCTTTCCATAGCGAGTGGTCTGGCTCACCTGCACATGGAGATCGTGGGTACTCAAGGTAAGCC
  TGCTATTGCTCACCGAGATATAAAGTCAAAGAATATCCTAGTCAAAAAATGTGACACTTGTGCCATAGCT
  GACTTAGGGCTGGCTGTGAAGCACGATTCTATCATGAACACTATAGACATACCCCAGAATCCTAAAGTGG
  GAACCAAGAGGTACATGGCTCCCGAAATGCTTGATGATACAATGAACCTGAGCATCTTTGAGTCCTTCAA
  GCGAGCTGACATCTATTCGGTGGGGCTGGTTTACTGGGAAATAGCTCGAAGGTGTTCAGTTGGAGGAGTT
  GTTGAGGAGTACCAGTTGCCTTACTATGACATGGTGCCTTCAGATCCTTCGATAGAAGAAATGAGGAAGG
  TTGTCTGTGATCAGAAACTCCGACCAAATCTCCCAAACCAGTGGCAAAGCTGTGAAGCGCTGCGGGTCAT
  GGGAAGAATAATGCGTGAGTGCTGGTACGCCAACGGGGCAGCACGCCTGACAGCCCTGCGCGTGAAGAAG
  ACCATCTCCCAGCTGTGTGTCAAGGAAGACTGTAAAGCTTAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001033369
• Insert Size: 1092 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001033369.3, NP_001028541.1
• RefSeq Size: 8666 bp
• RefSeq ORF: 1092 bp
• Locus ID: 269275
• Cytogenetics: 2 C1.1
• Gene Summary: Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis. [UniProtKB/Swiss-Prot Function]