Gfra2 (NM_008115) Mouse Untagged Clone

CAT#: MC216255

Gfra2 (untagged) - Mouse glial cell line derived neurotrophic factor family receptor alpha 2 (Gfra2), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Gfra2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC216255 representing NM_008115
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGATCTTGGCAAACGCCTTCTGCCTCTTCTTCTTTTTAGACGAAACCCTCCGCTCTTTGGCCAGCCCTT
  CCTCTCCGCAGGGCTCTGAGCTCCACGGCTGGCGCCCCCAAGTGGACTGTGTCCGGGCCAATGAGCTGTG
  TGCGGCTGAATCCAACTGCAGCTCCAGGTACCGCACCCTTCGGCAGTGCCTGGCAGGCCGGGATCGCAAT
  ACCATGCTGGCCAATAAGGAGTGCCAGGCGGCCCTGGAGGTCTTGCAGGAAAGCCCATTGTATGACTGCC
  GCTGCAAGCGGGGCATGAAGAAGGAGCTGCAGTGTCTGCAGATCTATTGGAGCATCCATCTGGGGCTGAC
  GGAGGGTGAGGAGTTCTACGAAGCTTCGCCCTATGAGCCTGTGACCTCCCGCCTCTCGGACATCTTCAGG
  CTCGCTTCAATCTTCTCAGGGACAGGGGCAGACCCGGTGGTCAGTGCCAAGAGCAACCACTGCCTGGATG
  CCGCCAAGGCCTGCAACCTGAACGACAACTGCAAGAAGCTCCGCTCCTCCTACATCTCCATCTGCAACCG
  CGAGATCTCTCCCACCGAACGCTGCAACCGCCGCAAGTGCCACAAGGCCCTGCGCCAGTTCTTCGACCGT
  GTGCCCAGCGAGTATACCTACCGCATGCTCTTCTGCTCCTGTCAGGACCAGGCATGCGCCGAGCGTCGCC
  GGCAAACCATCCTGCCCAGCTGTTCCTATGAGGACAAAGAGAAGCCCAATTGCTTGGACCTGCGCAGCCT
  GTGTCGTACAGACCACTTGTGCCGGTCCCGCCTGGCAGACTTCCACGCCAACTGTCGAGCCTCCTACCGG
  ACAATCACCAGCTGCCCTGCGGACAACTACCAGGCATGTCTGGGCTCCTATGCTGGCATGATTGGGTTTG
  ATATGACACCGAACTATGTGGACTCCAACCCCACGGGCATCGTGGTGTCTCCCTGGTGCAATTGTCGTGG
  CAGTGGGAACATGGAAGAAGAGTGTGAGAAGTTCCTCAAGGACTTCACAGAAAACCCATGCCTCCGGAAT
  GCCATTCAAGCCTTTGGCAATGGCACAGATGTGAACATGTCTCCCAAAGGCCCCACATTTTCAGCTACCC
  AGGCCCCTCGGGTAGAGAAAACTCCTTCACTGCCAGATGACCTCAGTGATAGCACCAGCCTGGGGACCAG
  TGTCATCACCACCTGCACATCTATCCAGGAGCAAGGGCTGAAGGCCAACAACTCCAAAGAGTTAAGCATG
  TGTTTCACAGAGCTCACGACAAATATCAGCCCAGGGAGTAAAAAGGTGATCAAACTTTACTCAGGCTCCT
  GCAGAGCCAGACTGTCGACTGCCTTGACTGCCCTCCCACTCCTGATGGTGACCTTGGCCCAGTAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_008115
• ORF Size: 1395 bp
• Insert Size: 1395
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_008115.3, NP_032141.2
• RefSeq Size: 3487
• RefSeq ORF: 1395
• Locus ID: 14586
• Gene Summary: The protein encoded by this gene is part of the receptor complex that transduces glial cell-derived neurotrophic factor and neurturin signals by mediating autophosphorylation and activation of the RET receptor. Mice lacking this protein are viable and fertile but display growth retardation attributed to impaired salivary and pancreatic secretion and innervation deficits in the intestinal tract. In addition, knockout mice display neural defects including a failure to initiate outgrowth of dorsal ganglion root neurons, demonstrating a requirement in neuronal differentiation of these cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).