F10 (NM_007972) Mouse Untagged Clone

CAT#: MC216596

F10 (untagged) - Mouse coagulation factor X (F10), (10ug)


  "NM_007972" in other vectors (4)

Reconstitution Protocol

USD 660.00

3 Weeks*

Size
    • 10 ug

Product Images

Specifications

Product Data
Type Mouse Untagged Clone
Tag Tag Free
Symbol F10
Synonyms Cf10; fX
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>MC216596 representing NM_007972
Red=Cloning site Blue=ORF Orange=Stop codon

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGGGGAGCCCGGTGCAACTCAGCCTGCTCTGTGTTGTCCTGGCCAGCCTCCTGCTCCCTGGGAAAGGTG
TGTTTATTAACCGGGAACGTGCCAACAATGTCCTGGCGAGGACTCGGAGGGCAAACTCATTTTTTGAAGA
GTTCAAGAAAGGAAATCTGGAAAGAGAGTGTATGGAAGAAATTTGTTCTTATGAAGAGGTCCGTGAAATC
TTCGAGGACGACGAGAAGACGAAAGAATACTGGACCAAATATAAAGACGGCGACCAGTGTGAAAGCAGCC
CTTGCCAGAACCAAGGAGCGTGTCGAGATGGCATCGGGGGTTACACGTGCACCTGCTCGGAGGGATTTGA
AGGCAAAAACTGTGAGCTCTTTGTTCGGAAACTCTGCCGCCTAGACAACGGAGACTGTGACCAGTTCTGC
AGAGAAGAGCAGAACTCAGTGGTGTGCTCCTGCGCCAGCGGTTACTTCCTGGGTAATGATGGCAAGTCTT
GCATCTCCACAGCTCCCTTCCCCTGTGGAAAAATCACTACAGGACGTAGGAAGAGGTCTGTGGCCCTAAA
CACCAGCGACAGTGAGCTTGACCTTGAAGACGCCCTGCTTGATGAGGATTTCCTGTCCCCTACGGAGAAT
CCTATTGAACTGCTCAACCTCAACGAGACACAGCCTGAGAGGAGCAGCGATGACCTTGTTCGGATTGTGG
GTGGCCGGGAATGCAAGGATGGAGAATGTCCCTGGCAGGCTCTGCTCATTAACGAAGACAATGAAGGGTT
CTGTGGGGGCACCATCTTGAATGAGTTCTACATCCTCACTGCTGCCCACTGTCTCCATCAGGCCAGGCGA
TTCAAGGTGAGGGTAGGTGATCGGAACACAGAGAAGGAAGAAGGCAACGAGATGGTGCACGAGGTGGACG
TGGTCATTAAGCACAACAAGTTTCAGAGGGACACCTACGACTATGATATCGCCGTGCTGAGGCTGAAGAC
TCCCATCACGTTCCGGATGAACGTGGCCCCTGCCTGCCTGCCTCAGAAAGACTGGGCCGAGTCCACACTG
ATGACACAGAAGACGGGCATCGTGAGCGGGTTTGGACGCACGCATGAGAAGGGCCGCCAGTCGAACATCC
TGAAGATGCTGGAGGTACCCTACGTGGATCGCAACACCTGCAAGCTCTCCACCAGCTTCAGCATCACACA
GAATATGTTCTGTGCGGGCTATGAGGCCAAGTTAGAGGATGCCTGCCAGGGGGACAGTGGTGGCCCCCAT
GTCACACGGTTCAAAAATACCTACTATGTGACCGGCATTGTCAGCTGGGGAGAGGGGTGTGCAAGGAAAG
GGAAATATGGCATCTACACAAAGGTCACGACCTTCCTCAAGTGGATTGACAGGTCCATGAAAGCCAGGGT
GGGACCCACAGCCGAGACCCCAAGGACAGCAGGTCCGCCCAATTAA


ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites SgfI-MluI     
ACCN NM_007972
ORF Size 1446 bp
Insert Size 1446
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq NM_007972.4, NP_031998.3
RefSeq Size 2503
RefSeq ORF 1446
Locus ID 14058
Gene Summary This gene encodes factor X, a component of both the intrinsic and extrinsic blood coagulation pathways. The encoded protein is a zymogen that undergoes further processing in a vitamin K-dependent manner to generate mature factor X, a heterodimer comprised of disulfide-linked heavy and light chains. The mature factor X is proteolytically activated either by factor IXa (intrinsic pathway) or factor VIIa (extrinsic pathway) to form factor Xa serine endopeptidase. Activated factor Xa catalyzes the conversion of prothrombin to thrombin. A complete lack of the encoded protein is fatal to mice. A severe deficiency of the encoded protein in mice causes age-dependent iron deposition and cardiac fibrosis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]
Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream, in-frame start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

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