Acvr1c (NM_001111030) Mouse Untagged Clone

CAT#: MC216909

Acvr1c (untagged) - Mouse activin A receptor, type IC (Acvr1c), transcript variant 1, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Acvr1c
• Synonyms: ACTR-IC; ACVRLK7; Alk-7; ALK7; C230097P10
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC216909 representing NM_001111030
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGACCCCAGCGCGCGGCTCCGCACTGAGCCTGGCCCTCCTGCTGGTGGCCCTGGCCGCCGACCTTGCGG
  CAGGACTGAAGTGTGTGTGTCTTTTGTGTGATTCTTCAAACTTCACCTGCCAAACGGAAGGAGCATGTTG
  GGCCTCCGTCATGCTAACCAACGGGAAAGAGCAGGTGATCAAATCGTGTGTGTCCCTCCCGGAACTAAAT
  GCTCAGGTCTTCTGTCACAGTTCCAACAACGTGACCAAAACCGAATGTTGCTTCACAGACTTCTGCAACA
  ATATCACACTGCACCTTCCCACAGCATCGCCAAATGCCCCTCGACTTGGTCCCACAGAGCTGACGGTTGT
  TATCACCGTGCCGGTTTGCCTCCTGTCCATAGCCGCCATGCTAACAATATGGGCGTGCCAGGACCGCCAG
  TGCACATACAGGAAGACTAAGAGACACAACGTGGAGGAAGCGCTGGCTGAGTACAGCCTTGTGAATGCAG
  GAAAAACACTCAAGGATCTGATCTACGATGCTACTGCCTCTGGCTCAGGCTCTGGTCTGCCTCTCTTGGT
  TCAAAGAACAATCGCAAGGACAATTGTACTTCAAGAAATCGTAGGAAAAGGTCGGTTTGGGGAAGTGTGG
  CACGGAAGATGGTGTGGAGAAGATGTGGCTGTGAAAATATTCTCCTCCAGGGATGAGAGATCTTGGTTCC
  GTGAGGCGGAAATTTATCAGACGGTGATGCTGAGACACGAGAACATCCTCGGTTTCATCGCAGCTGACAA
  CAAAGATAATGGAACTTGGACACAACTCTGGCTTGTGTCAGAGTATCACGAGCAGGGCTCCTTGTATGAC
  TATTTGAACAGAAACATAGTGACTGTGGCTGGAATGGTCAAGCTGGCGCTTTCCATAGCGAGTGGTCTGG
  CTCACCTGCACATGGAGATCGTGGGTACTCAAGGTAAGCCTGCTATTGCTCACCGAGATATAAAGTCAAA
  GAATATCCTAGTCAAAAAATGTGACACTTGTGCCATAGCTGACTTAGGGCTGGCTGTGAAGCACGATTCT
  ATCATGAACACTATAGACATACCCCAGAATCCTAAAGTGGGAACCAAGAGGTACATGGCTCCCGAAATGC
  TTGATGATACAATGAACCTGAGCATCTTTGAGTCCTTCAAGCGAGCTGACATCTATTCGGTGGGGCTGGT
  TTACTGGGAAATAGCTCGAAGGTGTTCAGTTGGAGGAGTTGTTGAGGAGTACCAGTTGCCTTACTATGAC
  ATGGTGCCTTCAGATCCTTCGATAGAAGAAATGAGGAAGGTTGTCTGTGATCAGAAACTCCGACCAAATC
  TCCCAAACCAGTGGCAAAGCTGTGAAGCGCTGCGGGTCATGGGAAGAATAATGCGTGAGTGCTGGTACGC
  CAACGGGGCAGCACGCCTGACAGCCCTGCGCGTGAAGAAGACCATCTCCCAGCTGTGTGTCAAGGAAGAC
  TGTAAAGCTTAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001111030
• ORF Size: 1482 bp
• Insert Size: 1482
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_001111030.1, NP_001104500.1
• RefSeq Size: 9033
• RefSeq ORF: 1482
• Locus ID: 269275
• Gene Summary: Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis. [UniProtKB/Swiss-Prot Function]