Sptlc2 (NM_011479) Mouse Untagged Clone

CAT#: MC218920

Sptlc2 (untagged) - Mouse serine palmitoyltransferase, long chain base subunit 2 (Sptlc2), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Sptlc2
• Synonyms: LCB2; LCB2a; Spt2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC218920 representing NM_011479
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCGGCCGGAGCCCGGAGGCTGCTGCTGCCGCCGCCCGATGCGGGCGAACGGCTGCGTCAAGAACGGGG
  AAGTGAGGAACGGGTACTTGAGGAGCAGCACCGCCACCGTCGCGGCTGCCGGCCAGATTCATCATGTAAC
  AGAAAATGGAGGACTGTACAAAAGACCGTTTAATGAAGCTTTTGAAGAAACACCCATGCTGGTTGCTGTG
  CTCACATATGTGGGCTATGGCGTACTCACCCTCTTTGGATATCTTCGAGATTTCTTGAGGCATTGGAGAA
  TTGAAAAGTGCCACCATGCAACAGAAAGAGAAGAACAAAAGGACTTTGTGTCCTTGTATCAGGATTTTGA
  AAACTTCTATACAAGGAACCTCTACATGAGAATCAGAGACAACTGGAATCGACCTATCTGTAGTGTGCCT
  GGAGCCAAGGTGGATATCATGGAGAGAAAATCTCATGACTATAACTGGTCATTCAAGTACACAGGGAATA
  TAATTAAAGGTGTAATAAACATGGGTTCCTACAACTATCTTGGATTTGCGAGGAACACTGGATCATGTCA
  GGAAGCAGCTGCTGAAGTCCTCAAGGAGTATGGAGCAGGGGTGTGCAGCACTCGTCAGGAAATTGGAAAC
  CTGGACAAGCATGAAGAACTAGAGAAATTGGTAGCAAGGTTCTTAGGTGTGGAAGCTGCTATGACCTATG
  GCATGGGATTTGCAACAAATTCAATGAACATTCCTGCTCTTGTTGGCAAAGGTTGCCTGATTCTGAGTGA
  TGAGCTGAACCATGCGTCACTGGTTCTAGGAGCCAGACTGTCAGGAGCAACCATTCGAATCTTCAAACAC
  AACAATATGCAAAGCTTAGAGAAGCTTTTAAAAGATGCCATTGTTTATGGTCAGCCTCGGACAAGAAGAC
  CCTGGAAGAAAATCTTAATCCTTGTGGAAGGCATATATAGTATGGAGGGGTCTATTGTTCGCCTTCCTGA
  AGTGATTGCTCTCAAGAAGAAATACAAGGCATACTTGTATCTGGATGAGGCTCACAGCATTGGGGCTCTT
  GGCCCTTCAGGGCGAGGCGTGGTAGATTACTTTGGCCTGGATCCTGAGGATGTAGATGTTATGATGGGAA
  CATTCACAAAGAGCTTCGGTGCTTCAGGAGGATACATCGGAGGCAAGAAGGAGCTGATAGACTACCTGCG
  CACACATTCTCACAGTGCTGTGTATGCCACGTCGATGTCACCGCCTGTGATGGAACAGATTATCACCTCC
  ATGAAGTGCATCATGGGGCAGGATGGCACCAGTCTTGGCAAAGAATGTATACAGCAGTTGGCTGAGAACA
  CCAGGTATTTCAGGAGACGCCTGAAGGAAATGGGGTTCATCATCTATGGCAATGAAGACTCCCCGGTGGT
  GCCTTTGATGCTCTACATGCCGGCCAAAATTGGCGCCTTTGGAAGAGAGATGCTGAAGCGGAACATTGGT
  GTAGTTGTGGTGGGATTTCCTGCTACCCCGATCATTGAGTCCAGAGCCAGATTTTGCCTGTCAGCAGCTC
  ATACCAAAGAAATACTTGACACTGCTTTGAAGGAGATAGATGAAGTTGGGGATCTGCTGCAGCTAAAGTA
  CTCTCGCCACCGGCTGGTGCCTCTACTGGACAGGCCCTTTGATGAGACTACCTATGAAGAGACAGAAGAC
  TGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_011479
• ORF Size: 1683 bp
• Insert Size: 1683
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_011479.4, NP_035609.1
• RefSeq Size: 6725
• RefSeq ORF: 1683
• Locus ID: 20773
• Gene Summary: This gene encodes a long chain base subunit of serine palmitoyltransferase. The enzyme, serine palmitoyltransferase, consists of two different subunits, and is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. A mutant allele of this gene in mice is used as a model for the human disease 'Susceptibilty to Psoriasis 1'. Mutations in the human gene are associated with hereditary sensory neuropathy type I. [provided by RefSeq, Sep 2015]