Mag (NM_010758) Mouse Untagged Clone

CAT#: MC219276

Mag (untagged) - Mouse myelin-associated glycoprotein (Mag), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Mag
• Synonyms: Gma; siglec-4a
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC219276 representing NM_010758
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGATATTCCTCGCCACCCTGCCGCTGTTTTGGATAATGATTTCAGCTTCTCGAGGGGGCCACTGGGGTG
  CCTGGATGCCCTCGACCATCTCAGCCTTCGAGGGCACGTGTGTCTCCATTCCCTGCCGTTTCGACTTCCC
  CGATGAGCTCAGACCGGCTGTGGTACATGGCGTCTGGTATTTCAATAGTCCCTACCCCAAGAACTACCCA
  CCGGTGGTCTTCAAGTCCCGCACACAAGTGGTCCATGAGAGTTTCCAGGGCCGCAGCCGCCTATTGGGAG
  ACCTGGGCCTACGAAACTGTACCCTGCTTCTCAGCACACTGAGCCCCGAGCTGGGAGGCAAATACTATTT
  CCGAGGCGACCTGGGTGGCTACAACCAGTACACCTTCTCGGAGCACAGCGTCCTGGACATCGTCAACACC
  CCCAACATTGTGGTTCCCCCGGAAGTGGTGGCAGGAACGGAAGTGGAGGTCAGTTGTATGGTGCCGGACA
  ACTGCCCAGAGCTGCGGCCAGAGCTGAGCTGGCTGGGCCACGAGGGGCTGGGAGAGCCCACTGTGCTGGG
  TCGGCTGCGTGAGGATGAAGGCACCTGGGTGCAGGTGTCGCTGCTACACTTCGTGCCTACTAGAGAGGCC
  AACGGCCACCGTCTGGGCTGTCAGGCTGCCTTCCCCAACACCACCTTGCAGTTCGAGGGTTACGCCAGTT
  TGGACGTCAAGTACCCCCCAGTGATTGTGGAGATGAATTCCTCTGTGGAGGCCATTGAGGGCTCCCATGT
  CAGCCTGCTCTGTGGGGCTGACAGCAACCCGCCGCCGCTGCTGACTTGGATGCGGGATGGGATGGTGTTG
  AGGGAGGCAGTTGCCAAGAGCCTGTACCTGGATCTGGAGGAGGTGACCCCAGGAGAGGACGGCGTCTATG
  CTTGCCTAGCAGAGAACGCCTATGGCCAGGACAACCGCACGGTGGAGCTGAGTGTCATGTATGCACCTTG
  GAAGCCCACAGTGAATGGGACGGTGGTGGCCGTAGAGGGGGAGACTGTCTCTATCCTGTGTTCCACACAG
  AGCAACCCGGACCCCATCCTTACCATCTTCAAGGAGAAGCAGATCCTAGCCACGGTCATCTATGAGAGTC
  AGCTGCAGCTGGAACTCCCTGCAGTGACCCCCGAGGATGATGGGGAATACTGGTGTGTGGCTGAGAACCA
  GTATGGCCAGAGAGCCACTGCCTTCAACCTGTCTGTGGAGTTTGCCCCCATAATCCTTCTGGAGTCACAC
  TGTGCAGCGGCCAGAGACACCGTGCAGTGTCTATGTGTGGTAAAATCCAACCCGGAACCCTCTGTGGCCT
  TTGAGCTGCCTTCCCGCAACGTGACTGTGAATGAGACGGAGAGGGAGTTTGTGTACTCCGAGCGCAGTGG
  CCTCCTGCTCACCAGCATCCTCACGATCCGGGGTCAGGCCCAAGCCCCACCCCGCGTCATTTGTACCTCC
  AGGAACCTCTATGGCACCCAGAGCCTCGAGCTGCCTTTCCAGGGAGCACACCGACTGATGTGGGCCAAAA
  TCGGTCCTGTGGGTGCTGTGGTCGCCTTTGCCATCCTGATTGCCATTGTGTGCTACATCACCCAGACGAG
  AAGAAAAAAGAATGTCACGGAGAGCTCCAGCTTCTCAGGGGGAGACAACCCTCATGTCCTGTACAGCCCC
  GAATTCAGAATCTCTGGGGCACCTGATAAGTATGAGTCCAGAGAGGTCTCTACCCGGGATTGTCACTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_010758
• ORF Size: 1749 bp
• Insert Size: 1749
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_010758.2, NP_034888.1
• RefSeq Size: 2427
• RefSeq ORF: 1749
• Locus ID: 17136
• Gene Summary: This gene encodes a type I membrane protein and member of the immunoglobulin-like superfamily. It is expressed in myelinating glial cells, including oligodendrocytes of the central nervous system and Schwann cells of the peripheral nervous system. Mice lacking the encoded protein express abundant myelin, but suffer long-term axon degeneration, altered distribution of channels and adhesion molecules at nodes of Ranvier, and altered axon cytoskeletal structure. While not required for myelination, the encoded protein enhances axon-myelin stability, helps to structure nodes of Ranvier, and regulates the axon cytoskeleton. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
  Transcript Variant: This variant (6) uses an alternate exon in the 3' coding region resulting in novel 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (3) has a shorter and distinct C-terminus, compared to isoform 1. Variants 4, 5, 6, and 7 encode the same isoform (3).