Suz12 (NM_199196) Mouse Untagged Clone

CAT#: MC221213

Suz12 (untagged) - Mouse suppressor of zeste 12 homolog (Drosophila) (Suz12), transcript variant 1, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Suz12
• Synonyms: 2610028O16Rik; AI195385; AU016842; AW536442; D11Ertd530e; mKIAA0160
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC221213 representing NM_199196
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCGCCTCAGAAGCACGGCGGTGGGGGAGGGGGCGGCTCGGGGCCCAGCGCGGGGTCCGGGGGAGGCG
  GCTTCGGGGGTTCGGCGGCGGCGGTGGCGGCGGCGGCTTCGGGCGGCAAATCCGGCGGCGGGGGCTGTGG
  AGGCGGCGGCAGTTACTCGGCCTCCTCCTCCTCGGCGGCGGCCGCGGCGGCGGCGGCGGGGGCCGCGGTG
  TTGCCGGTGAAGAAGCCGAAAATGGAGCACGTCCAGGCTGACCACGAGCTTTTCCTCCAGGCCTTTGAGA
  AACCAACACAGATATATAGATTTCTTCGAACTCGAAATCTTATCGCACCAATATTTTTGCACAGAACTCT
  TACTTACATGTCTCATCGAAATTCCAGAACAAGCATCAAAAGGAAAACATTTAAAGTTGATGATATGTTA
  TCAAAAGTAGAGAAAATGAAAGGAGAGCAAGAATCTCATAGCTTGTCTGCACATTTGCAACTTACATTTA
  CCGGTTTCTTCCACAAAAATGATAAGCCATCACAAAACTCAGAAAATGAACAAAATTCTGTTACCCTGGA
  AGTCCTGCTTGTGAAAGTTTGCCACAAAAAAAGGAAGGATGTAAGTTGTCCAATAAGACAAGTCCCTACT
  GGTAAAAAGCAGGTGCCTTTGAATCCTGACCTCAATCAAACAAAACCAGGAAATTTTCCATCCCTGGCAG
  TTTCCAGTAATGAATTTGAACCTAGTAACAGCCATATGGTGAAGTCCTACTCGTTGCTGTTTAGAGTAAC
  TCGTCCAGGAAGAAGAGAATTTAATGGAATGATTAATGGAGAAACCAATGAAAATATTGATGTCAGTGAA
  GAACTTCCAGCCAGAAGAAAACGAAATCGCGAAGATGGAGAAAAGACATTTGTTGCACAAATGACAGTTT
  TTGACAAAAACAGGCGTTTACAGCTTTTAGATGGGGAATATGAAGTGGCCATGCAGGAAATGGAAGAATG
  TCCAATAAGTAAGAAAAGAGCAACATGGGAGACAATTCTTGATGGGAAGAGGCTGCCTCCATTTGAGACA
  TTTTCTCAGGGACCTACATTACAATTTACTCTTCGATGGACAGGAGAAACCAACGATAAGTCTACAGCTC
  CTGTTGCCAAGCCTCTTGCCACTAGAAATTCAGAGAGCCTTCATCAGGAAAATAAGCCTGGTTCTGTTAA
  ACCTGCACAAACTATTGCTGTTAAGGAGACGCTGACTACAGAGCTGCAAACAAGAAAAGAAAAGGATAAT
  TCAAATGAAAGTCGCCAGAAGTTAAGAATATTTTATCAGTTCCTTTATAACAATAATACAAGACAACAGA
  CAGAAGCCAGAGACGACCTGCACTGCCCGTGGTGCACTCTGAACTGCCGTAAACTGTATAGCTTACTCAA
  ACATCTAAAGCTCTGCCACAGCAGGTTCATCTTCAATTACGTATATCATCCAAAAGGTGCTAGGATAGAT
  GTTTCAATCAATGAGTGTTATGATGGCTCCTATGCAGGAAATCCTCAGGATATACATCGCCAACCTGGAT
  TTGCTTTTAGTCGAAATGGACCGGTAAAGAGAACACCTATCACACATATTCTTGTTTGCAGGCCAAAAAG
  AACAAAAGCAAGCATGTCGGAGTTTCTTGAATCTGAAGATGGAGAAGTGGAGCAGCAGAGAACATACAGC
  AGTGGCCACAATCGTCTCTATTTCCACAGTGATACCTGCTTACCTCTTCGGCCACAAGAAATGGAAGTAG
  ATAGTGAAGATGAGAAAGATCCAGAATGGCTGAGAGAAAAAACCATTACTCAAATTGAAGAATTTTCTGA
  TGTGAATGAAGGAGAGAAAGAAGTGATGAAGCTGTGGAACCTCCATGTCATGAAGCATGGATTTATTGCT
  GACAATCAAATGAATCATGCCTGTATGCTGTTTGTAGAAAATTATGGACAGAAAATAATTAAGAAGAATT
  TATGTCGAAACTTCATGCTTCATCTAGTCAGCATGCATGACTTTAATCTTATTAGCATAATGTCAATAGA
  TAAAGCTGTTACCAAGCTCCGAGAAATGCAGCAAAAACTAGAAAAAGGAGAATCTGCGACCCCTTCAAAT
  GAAGAAATAGCTGAGGAACAAAATGGAACAGCAAATGGATTCAGTGAAACTAACTCAAAAGAGAAAGCTT
  TGGAAACTGACGGTGTCTCAGGGGTTCCAAAACAGAGCAAGAAACAAAAACTCTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_199196
• ORF Size: 2226 bp
• Insert Size: 2226
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_199196.2, NP_954666.1
• RefSeq Size: 4449
• RefSeq ORF: 2226
• Locus ID: 52615
• Gene Summary: This gene encodes a core component of the polycomb repressive complex 2 (PRC2) that also includes, at least, embryonic ectoderm development protein (EED) and enhancer of zeste homolog 1 or 2 (EZH1 or EZH2). Through the methyltransferase activity of EZH1 or EZH2, the PRC2 complex methylates Lys9 and Lys27 of histone 3 and Lys26 of histone 1, leading to recruitment of the PRC1 complex, histone 2A ubiquitylation and transcriptional repression of the target genes. This gene product is essential for the activity and integrity of the PRC2 complex, and is required for X chromosome inactivation, stem cell maintenance and differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).