Ltk (NM_206942) Mouse Untagged Clone

CAT#: MC221855

Ltk (untagged) - Mouse leukocyte tyrosine kinase (Ltk), transcript variant 3, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Ltk
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC221855 representing NM_206942
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGGCTGCTCCCACCGGCTGCTGCTGTGGCTGGGAGCTGCTGGAACTATTCTTTGCTCCAACTCGGAGT
  TCCAGACACCTTTTCTAACACCTTCGCTTTTGCCGGTGCTGGTACTCAATTCCCAGGAGCAGAAAGTCAC
  CCCCACACCCAGTAAATTGGAGCCAGCTTCCCTCCCAAATCCTCTAGGCACACGGGGGCCTTGGGTGTTT
  AACACCTGTGGCGCCAGCGGCAGGAGCGGACCCACACAAACACAGTGCGATGGGGCATACACAGGAAGCA
  GCGTGATGGTGACAGTGGGGGCTGCCGGGCCGCTCAAAGGCGTGCAGCTGTGGCGGGTGCCAGACACAGG
  CCAGTATCTGATCTCCGCCTACGGAGCGGCGGGCGGCAAGGGCGCCCAAAACCACCTGTCACGGGCGCAC
  GGCATCTTCCTCTCAGCAGTCTTCTTCCTCCGTCGCGGGGAGCCGGTGTACATCCTTGTGGGGCAGCAGG
  GCCAGGACGCCTGTCCCGGAGGGAGCCCTGAGAGCCAACTCGTCTGTCTGGGAGAGTCTGGGGAGCATGC
  AACCACCTATGGGACCGAAAGGATCCCAGGCTGGAGACGCTGGGCCGGCGGGGGCGGGGGTGGCGGAGGC
  GCCACCTCCATCTTCCGGCTGCGCGCGGGGGAGCCAGAGCCGCTGCTGGTGGCGGCGGGAGGCGGCGGGA
  GGTCCTACCGGAGGCGACCTGACCGCGGCCGGACTCAGGCCGTCCCCGAGAGGCTGGAGACCCGCGCGGC
  GGCGCCGGGCAGCGGCGGGAGAGGAGGCGCGGCAGGCGGTGATACTTCTGAGTCTGACCTCCTCTGGGCT
  GATGGGGAAGATGGCACATCCTTTGTCCACCCCAGTGGTGAGCTCTACCTACAGCCTCTGGCAGTCACAG
  AGGGCCATGGGGAGGTGGAGATCCGAAAGCATCCCAACTGCAGTCACTGCCCTTTCAAAGACTGCCAGTG
  GCAGGCAGAGCTCTGGACGGCCGAATGCACGTGCCCAGAGGGCACGGAGCTAGCTGTGGATAATGTCACT
  TGCATGGACCTGCCAACCACCGCAAGCCCTCTGATCCTGATGGGAGCTGTAGTGGCAGCCTTGGCACTGA
  GTCTCCTAATGATGTGTGCAGTCCTGATTCTAGTGAACCAGAAGTGTCAGGGCCTGTGGGGGACCAGGCT
  GCCAGGCCCTGAGCTTGAGCTAAGCAAGCTTCGATCCTCTGCCATCAGGACAGCACCCAACCCTTACTAT
  TGTCAGGTGGGACTCAGTCCTGCCCAGCCCTGGCCTTTGCCCCCAGGGCTCACTGAGGTTTCACCAGCCA
  ATGTCACTCTACTCAGAGCCCTTGGCCATGGTGCCTTTGGGGAAGTGTACGAGGGACTAGTGACTGGTCT
  TCCTGGGGACTCCAGTCCTCTTCCAGTGGCTATTAAGACTCTGCCAGAGCTCTGCTCCCATCAGGATGAG
  CTGGATTTTCTCATGGAGGCTCTGATCATCAGCAAGTTCAGCCATCAGAACATTGTACGCTGTGTGGGGC
  TCAGCTTTCGGTCTGCCCCGCGCCTCATTCTGCTGGAGCTGATGTCTGGTGGGGACATGAAGAGCTTTTT
  GAGGCACAGCAGACCACACCCAGGACAACTGGCACCTCTGACCATGCAGGACCTATTGCAGCTGGCCCAG
  GATATAGCCCAGGGCTGCCACTACCTGGAGGAAAATCACTTCATTCACAGAGACATTGCTGCCCGTAACT
  GTCTGCTTAGCTGCAGTGGAGCCAGCCGAGTGGCCAAGATTGGAGATTTTGGAATGGCAAGAGATATCTA
  CCAGGCCAGTTATTATCGCAAGGGTGGCCGGACCTTGCTCCCAGTCAAGTGGATGCCGCCAGAAGCTCTC
  CTGGAGGGCCTTTTCACATCCAAGACAGACTCCTGGTCTTTTGGGGTCCTGCTCTGGGAGATCTTCTCAC
  TGGGGTATATGCCCTACCCTGGACATACCAACCAGGAGGTTCTAGACTTCATTGCCACAGGGAACAGGAT
  GGACCCTCCTAGGAACTGTCCTGGGCCAGTGTACCGAATCATGACCCAGTGTTGGCAGCATCAGCCGGAG
  CTCCGCCCTGACTTTGGCAGCATCTTGGAACGGATTCAGTACTGCACTCAGGACCCTGATGTGCTGAACT
  CACCCCTGCCCGTGGAACCTGGGCCCATTCTAGAGGAGGAAGAGGCCTCCAGGCTGGGAAACAGGTCACT
  GGAGGGTCTTAGATCCCCAAAGCCCCTAGAGCTGAGTTCTCAGAACTTGAAGAGCTGGGGAGGAGGCCTT
  CTTGGCTCTTGGCTGCCCTCTGGCCTCAAGACCCTCAAACCCAGGTGCCTCCAACCTCAGAACATTTGGA
  ACCCCACCTATGGCTCCTGGACCCCAAGGGGCCCCCAGGGTGAAGATACAGGCATTGAACACTGCAATGG
  CTCCTCCTCAAGTTCCATTCCAGGCATCCAGTAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_206942
• ORF Size: 2484 bp
• Insert Size: 2484
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_206942.2, NP_996825.2
• RefSeq Size: 2932
• RefSeq ORF: 2484
• Locus ID: 17005
• Gene Summary: The protein encoded by this gene is a member of the ros/insulin receptor family of tyrosine kinases. Tyrosine-specific phosphorylation of proteins is a key to the control of diverse pathways leading to cell growth and differentiation. Four alternatively spliced transcript variants encoding different isoforms have been described for this gene. These transcripts are expressed in a tissue-specific manner in lymphocytes, brain and neuroblastoma cells, and the encoded isoforms exhibit different subcellular localization. The lymphocyte and brain specific variants initiate translation at non-AUG (CUG) start codons. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (3) is lacking an internal coding exon compared to transcript variant 4. This results in an isoform (C), which is missing a 61 aa segment compared to isoform D, and that is localized in the endoplasmic reticulum. This variant is expressed in neuroblastoma cells and initiates translation from the standard AUG start codon.