Adam12 (NM_007400) Mouse Untagged Clone

CAT#: MC222455

Adam12 (untagged) - Mouse a disintegrin and metallopeptidase domain 12 (meltrin alpha) (Adam12), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Adam12
• Synonyms: Mltna
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC222455 representing NM_007400
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCAGAGCGCCCGGCGCGGCGCGCGCCCCCCGCCCGCGCCCTCCTGCTGGCCCTGGCTGGGGCCCTGC
  TGGCGCCCCGTGCAGCCCGAGGGATGAGTTTGTGGGACCAGAGAGGAACTTACGAAGTGGCCAGAGCCTC
  CCTTCTGAGCAAGGACCCTGGGATCCCAGGACAGAGCATCCCAGCCAAGGATCATCCAGACGTGCTGACT
  GTGCAACTGCAGCTGGAGAGCCGAGACCTGATCCTCAGCCTGGAAAGGAATGAGGGACTCATTGCCAATG
  GCTTCACGGAGACCCATTATCTGCAAGATGGTACTGATGTCTCTCTCACTCGAAATCACACGGATCATTG
  TTACTACCATGGACATGTGCAAGGAGATGCTGCATCAGTGGTCAGCCTCAGTACTTGCTCTGGTCTCCGG
  GGACTTATCATGTTTGAAAATAAAACGTACAGCTTAGAGCCAATGAAAAACACCACTGACAGCTACAAAC
  TCGTCCCAGCTGAGAGCATGACGAACATCCAAGGGCTGTGTGGGTCACAGCATAACAAGTCCAACCTCAC
  CATGGAAGATGTCTCCCCTGGAACCTCTCAAATGCGGGCAAGAAGGCATAAGAGAGAGACCCTTAAGATG
  ACCAAGTACGTAGAGCTGGTTATTGTGGCAGACAACAGAGAGTTTCAGAGGCAAGGAAAAGACCTGGAGA
  AAGTTAAGCAGCGATTAATAGAGATCGCCAATCACGTTGACAAGTTTTACAGACCACTGAACATCCGGAT
  CGTGCTGGTAGGAGTGGAAGTGTGGAATGACATCGACAAATGCTCTATAAGCCAGGACCCATTCACCAGC
  CTCCATGAGTTTCTAGACTGGAGAAAGATAAAGCTTCTACCTCGAAAATCCCACGACAATGCTCAGCTTA
  TCAGTGGGGTTTATTTCCAAGGAACCACCATCGGCATGGCACCCATCATGAGCATGTGCACTGCAGAACA
  GTCTGGAGGAGTTGTCATGGACCATTCAGACAGCCCCCTTGGTGCCGCAGTGACCTTGGCACATGAGCTG
  GGCCACAACTTCGGGATGAACCATGACACACTGGAGAGGGGCTGCAGCTGCAGAATGGCCGCAGAGAAAG
  GAGGCTGCATCATGAACCCGTCCACGGGGTTCCCATTCCCCATGGTGTTCAGCAGCTGCAGCAGGAAGGA
  CCTGGAGGCTAGCCTGGAGAAGGGCATGGGGATGTGCCTCTTCAACCTACCAGAGGTCAAGCAGGCCTTT
  GGGGGCCGGAAGTGTGGAAATGGCTATGTGGAAGAGGGAGAAGAGTGTGACTGCGGAGAACCGGAGGAAT
  GCACGAATCGCTGCTGTAACGCTACCACCTGTACTCTGAAGCCAGATGCTGTGTGCGCGCACGGGCAGTG
  CTGTGAAGACTGTCAGCTGAAGCCTCCAGGAACTGCATGCAGGGGCTCCAGCAACTCCTGTGACCTCCCA
  GAATTCTGCACAGGGACTGCCCCTCACTGTCCAGCCAATGTGTACCTACATGATGGCCACCCGTGTCAGG
  GCGTGGATGGTTACTGCTACAACGGCATCTGCCAGACCCATGAGCAGCAGTGTGTCACGCTCTGGGGACC
  AGGTGCTAAACCGGCTCCTGGCATCTGCTTTGAGCGAGTCAACTCTGCAGGAGATCCTTATGGTAACTGT
  GGCAAAGACTCCAAGAGCGCCTTCGCCAAATGTGAGCTGAGAGATGCCAAGTGTGGGAAAATCCAGTGTC
  AAGGTGGTGCAAGCCGACCTGTCATTGGTACCAATGCTGTTTCCATAGAAACAAATATCCCACAGCAGGA
  AGGAGGTCGGATTCTGTGCCGGGGGACCCATGTGTACTTGGGTGATGACATGCCAGACCCAGGGCTTGTG
  CTTGCAGGAACAAAGTGTGCAGAAGGAAAAATCTGCCTCAATCGTCGATGTCAGAATATCAGTGTCTTCG
  GCGTTCACAAGTGTGCCATGCAGTGCCACGGCCGAGGGGTATGTAACAACAGGAAGAATTGCCACTGTGA
  AGCCCACTGGGCTCCACCCTTCTGTGACAAGTTTGGCTTTGGAGGAAGCACAGACAGTGGTCCCATCAGG
  CAAGCAGATAACCAGGGCTTGACTGTAGGAATCCTGGTGAGCATCCTGTGTCTGCTTGCTGCTGGATTTG
  TGGTGTATCTCAAAAGGAAGACGTTGATGCGGCTGCTGTTCACACATAAAAAAACCACCATGGAAAAGCT
  AAGGTGTGTGCACCCTTCCCGGACACCCAGTGGCCCTCACCTTGGCCAGGCTCACCACACCCCCGGGAAA
  GGCCTGCTGATGAACCGGGCACCACATTTCAATACCCCCAAGGACAGGCACTCGCTGAAATGCCAGAACA
  TGGACATCAGCAGGCCCCTCGACGCTCGAGCCGTCCCACAGCTTCAGTCACCTCAGCGAGTGCTCCTGCC
  TCTCCACCAGACCCCACGTGCACCCAGTGGCCCTGCCAGGCCCCTGCCCGCCAGTCCTGCAGTCAGGCAG
  GCCCAGGGCATTCGAAAACCCAGTCCTCCTCAGAAGCCTCTGCCTGCTGATCCACTGAGCAGGACTTCTC
  GGCTCACTAGTGCCTTGGTGAGGACCCCAGGGCAGCAGGAACCTGGGCACCGCCCAGCCCCCATCAGACC
  TGCCCCTAAGCATCAAGTACCCAGACCTTCCCACAATGCCTATATCAAGTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_007400
• ORF Size: 2712 bp
• Insert Size: 2712
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_007400.2, NP_031426.2
• RefSeq Size: 7675
• RefSeq ORF: 2712
• Locus ID: 11489
• Gene Summary: This gene encodes a member of a disintegrin and metalloprotease (ADAM) family of endoproteases that play important roles in various biological processes including cell signaling, adhesion and migration. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional protein that localizes to the cell surface. About a third of the mice lacking the encoded protein die before weaning. Overexpression of the encoded protein in a mouse model of Duchenne muscular dystrophy alleviates the muscle pathology by preventing cell necrosis and inflammation. [provided by RefSeq, May 2016]