Enpp1 (NM_008813) Mouse Untagged Clone

CAT#: MC222520

Enpp1 (untagged) - Mouse ectonucleotide pyrophosphatase/phosphodiesterase 1 (Enpp1), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Enpp1
• Synonyms: 4833416E15Rik; AI428932; C76301; CD203c; E-NPP 1; E-NPP1; Ly-41; M6S1; NPP1; Npps; PC-1; Pca; Pca-1; Pdnp1; ttw; twy
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC222520 representing NM_008813
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGAGCGCGACGGCGACCAGGCAGGGCACGGGCCCCGGCACGGGTCAGCGGGAAACGGTCGCGAGCTCG
  AGTCACCAGCCGCGGCTTCGCTGCTCGCGCCCATGGACCTAGGAGAGGAGCCGCTGGAGAAGGCGGAGCG
  TGCCCGCCCTGCCAAAGACCCCAACACCTACAAAGTGCTGTCGCTGGTTTTGTCAGTATGTGTGCTAACA
  ACAATTCTTGGTTGTATATTTGGGTTGAAACCAAGCTGCGCCAAAGAAGTAAAAAGTTGCAAAGGCCGCT
  GCTTTGAAAGGACGTTCAGCAACTGTCGCTGTGATGCTGCCTGTGTCAGCCTTGGGAACTGCTGTCTGGA
  TTTCCAGGAGACCTGTGTGGAACCAACACATATATGGACTTGCAACAAATTCAGGTGCGGTGAGAAGAGG
  CTGTCCAGGTTCGTGTGCTCCTGTGCAGACGACTGCAAAACCCACAATGACTGTTGCATCAACTACAGTT
  CTGTGTGCCAAGATAAGAAGAGTTGGGTAGAAGAAACATGTGAAAGCATCGATACCCCGGAGTGTCCAGC
  AGAGTTTGAATCACCCCCTACTCTCTTGTTTTCTTTGGATGGATTCAGAGCTGAGTATTTGCACACCTGG
  GGTGGACTTCTTCCTGTCATTAGCAAGCTGAAAAACTGTGGAACATACACTAAAAACATGAGGCCTATGT
  ACCCTACCAAGACGTTTCCCAATCATTACAGCATCGTCACAGGACTTTATCCGGAATCCCATGGCATAAT
  TGATAACAAGATGTATGATCCCAAAATGAATGCTTCTTTCTCGCTTAAAAGTAAAGAGAAATTCAACCCT
  TTGTGGTACAAAGGACAGCCGATTTGGGTGACCGCTAATCATCAGGAGGTCAAGTCCGGCACATACTTTT
  GGCCAGGATCAGATGTGGAGATTGACGGGATTCTACCAGATATCTACAAAGTGTATAATGGGTCAGTACC
  ATTTGAAGAAAGGATTTTAGCTGTTCTTGAGTGGCTGCAGCTTCCTAGCCATGAAAGACCACACTTTTAC
  ACTCTGTATTTAGAAGAACCAGATTCTTCAGGGCATTCACATGGACCAGTCAGCAGCGAGGTCATCAAGG
  CCTTGCAGAAGGTTGACCGCCTGGTCGGCATGCTGATGGACGGCCTGAAGGACCTGGGCTTGGATAAATG
  CCTGAACCTCATCCTCATTTCAGATCACGGCATGGAACAAGGCAGCTGTAAGAAGTATGTGTACCTGAAT
  AAGTACTTGGGGGATGTGAACAATGTGAAAGTTGTGTATGGACCTGCTGCTCGGTTGAGACCCACTGATG
  TTCCAGAGACATACTATTCATTTAACTATGAAGCCCTTGCAAAAAATCTTTCTTGCCGGGAGCCAAACCA
  GCATTTCCGGCCTTACCTGAAACCCTTCTTACCCAAGCGCTTACACTTCGCTAAAAGTGACCGGATTGAG
  CCCCTGACCTTCTACCTGGACCCTCAGTGGCAACTTGCGTTGAATCCATCAGAGAGGAAATATTGTGGAA
  GTGGATTTCATGGCTCTGACAACTTGTTTTCAAACATGCAAGCTCTTTTTATTGGCTATGGACCTGCCTT
  CAAGCATGGTGCTGAAGTTGACTCCTTTGAAAATATTGAAGTCTATAACTTAATGTGTGACTTACTGGGT
  TTGATCCCAGCTCCCAATAATGGAAGTCATGGCAGCCTTAACCACCTTCTAAAGAAACCCATTTACAACC
  CAAGTCATCCCAAAGAAGAGGGCTTCCTGTCTCAGTGTCCAATCAAATCAACATCCAATGACCTCGGCTG
  CACATGTGACCCTTGGATTGTGCCAATCAAGGACTTTGAGAAACAGCTTAATCTGACCACAGAAGATGAT
  GACATTTACCATATGACTGTACCCTACGGGAGGCCCCGGATTCTACTGAAGCAGCACCGCGTCTGTCTAC
  TCCAGCAGCAACAGTTCTTGACCGGATACAGCCTGGACCTCCTCATGCCCCTCTGGGCGTCTTACACCTT
  CCTCAGTAATGACCAATTCTCCAGAGATGACTTTTCCAACTGTCTGTACCAGGATCTTCGGATTCCCCTT
  AGTCCTGTGCATAAATGTTCCTATTACAAAAGCAATTCTAAGCTAAGTTATGGGTTCCTCACGCCACCGA
  GACTAAATAGAGTTTCAAATCACATATACTCTGAAGCGCTGCTTACATCTAATATAGTGCCAATGTATCA
  GAGTTTTCAAGTTATATGGCACTACCTTCATGACACCCTACTGCAAAGGTATGCCCATGAAAGGAACGGC
  ATCAATGTTGTCAGCGGTCCCGTGTTTGACTTTGATTATGACGGACGCTATGATTCCTTAGAGATCCTGA
  AACAAAACAGCAGAGTCATCCGAAGCCAGGAAATTCTGATTCCGACTCACTTCTTCATTGTGCTCACCAG
  CTGCAAGCAGCTGTCTGAGACTCCCTTGGAGTGCTCCGCCTTAGAGTCCTCAGCTTACATACTGCCTCAT
  AGGCCTGATAACATTGAGAGCTGTACGCATGGGAAGCGGGAGTCTTCATGGGTCGAGGAGTTGCTGACCT
  TGCACAGAGCTCGGGTCACAGACGTGGAACTCATCACTGGCCTCAGCTTCTACCAGGACCGACAAGAGTC
  AGTTTCAGAACTGCTGAGGTTGAAAACACATTTGCCAATCTTCAGCCAAGAAGACTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_008813
• ORF Size: 2718 bp
• Insert Size: 2718
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_008813.4, NP_032839.3
• RefSeq Size: 6791
• RefSeq ORF: 2718
• Locus ID: 18605
• Gene Summary: This gene encodes a member of the nucleoside pyrophosphatase/phosphodiesterase family of enzymes that catalyzes the hydrolysis of pyrophosphate and phosphodiester bonds in nucleotide triphosphates and oligonucleotides, respectively, to generate nucleoside 5'-monophosphates. The encoded protein is a type II transmembrane glycoprotein that negatively regulates bone mineralization. Mice harboring a nonsense mutation in this gene, termed tiptoe walking (ttw), exhibit ectopic ossification of the spinal ligaments. The encoded protein binds to the insulin receptor, inhibits downstream signaling events and induces insulin resistance and glucose tolerance. This gene is located adjacent to a paralog on chromosome 10. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
  Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.