Diaph1 (NM_007858) Mouse Untagged Clone

CAT#: MC224083

Diap1 (untagged) - Mouse diaphanous homolog 1 (Drosophila) (Diap1), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Diaph1
• Synonyms: D18Wsu154e; Dia1; Diap1; Drf1; p140mDia
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC224083 representing NM_007858
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGAGCCGTCCGGCGGGGGCCTGGGGCCCGGCCGCGGTACCCGGGACAAGAAGAAGGGTCGGAGCCCGG
  ATGAGCTGCCTGCGACGGGCGGCGACGGCGGCAAACATAAGAAATTTCTGGAGAGATTTACCAGCATGAG
  GATTAAGAAGGAGAAAGAAAAGCCCAATTCTGCTCATAGAAACTCCTCTGCATCGTACGGAGATGACCCC
  ACTGCTCAGTCATTGCAGGACATCTCAGACGAGCAAGTTCTTGTCCTCTTTGAGCAGATGCTGGTGGATA
  TGAACCTGAATGAGGAGAAGCAGCAGCCTTTGCGAGAGAAGGACATTGTCATCAAGAGGGAGATGGTGTC
  GCAATATCTGCACACTTCCAAGGCTGGCATGAACCAGAAAGAGAGCTCTAGGTCTGCCATGATGTACATC
  CAGGAGCTGAGGTCGGGCTTGCGGGATATGCACCTGCTTAGCTGCCTTGAGTCCCTTCGAGTCTCTCTCA
  ACAATAACCCTGTCAGTTGGGTGCAGACATTTGGTGCTGAGGGCCTAGCCTCCTTATTGGACATCCTCAA
  ACGACTCCATGATGAGAAAGAGGAGACTTCTGGAAACTACGACAGCCGAAACCAGCATGAGATTATCCGC
  TGTTTGAAGGCTTTCATGAACAACAAGTTTGGAATCAAAACTATGTTGGAGACGGAAGAAGGAATCCTAC
  TGCTGGTCAGAGCCATGGATCCTGCTGTTCCCAATATGATGATTGATGCAGCAAAGCTGCTGTCTGCCCT
  CTGTATCCTGCCGCAGCCGGAGGACATGAATGAACGAGTTCTAGAGGCAATGACAGAGAGAGCTGAAATG
  GATGAGGTCGAACGCTTCCAGCCACTTCTGGACGGATTAAAAAGTGGGACCTCTATTGCCCTCAAAGTGG
  GATGCCTACAGCTCATCAATGCTCTCATCACTCCAGCTGAGGAACTGGACTTCCGAGTTCACATCCGAAG
  TGAGCTGATGCGCCTGGGGCTGCATCAGGTGTTGCAGGAGCTTCGAGAGATTGAAAATGAAGATATGAAA
  GTACAGCTGTGCGTGTTTGATGAACAAGGGGATGAAGATTTCTTTGATCTGAAGGGACGGCTGGATGATA
  TCCGCATGGAGATGGATGACTTTGGTGAAGTTTTTCAGATTATTTTAAACACAGTGAAAGATTCAAAGGC
  AGAGCCACACTTCCTGTCTATCTTGCAGCATCTCCTGTTGGTCCGAAATGATTATGAAGCCAGGCCACAG
  TACTATAAACTGATTGAAGAATGTGTTTCTCAGATAGTTCTACACAAAAATGGAACTGATCCTGACTTCA
  AGTGCCGACACCTGCAGATTGATATTGAGAGATTGGTTGATCAAATGATTGATAAAACAAAGGTGGAAAA
  ATCTGAGGCCAAAGCTACAGAGCTGGAAAAAAAGTTGGATTCAGAATTAACAGCGCGGCACGAGTTACAA
  GTAGAAATGAAAAAGATGGAAAATGACTTTGAGCAGAAACTTCAGGATCTTCAAGGAGAAAAGGATGCCT
  TGGATTCTGAAAAGCAGCAGATCACTGCACAGAAACAAGACCTGGAGGCAGAGGTGTCCAAGCTGACAGG
  AGAGGTTGCCAAGCTGTCAAAAGAACTAGAAGATGCCAAGAATGAAATGGCTTCTCTCTCTGCTGTGGTT
  GTTGCACCTTCTGTTTCTAGCAGTGCTGCTGTTCCCCCTGCCCCTCCTCTGCCTGGTGACTCTGGCACTG
  TTATTCCACCTCCCCCACCCCCACCTCCTCTTCCTGGAGGTGTGGTCCCACCATCCCCTCCTCTGCCTCC
  AGGTACTTGTATCCCTCCACCTCCTCCTTTACCTGGAGGTGCTTGTATACCCCCTCCCCCCCAGTTGCCT
  GGCAGTGCTGCCATCCCTCCACCTCCTCCTCTACCTGGAGTTGCTTCCATCCCCCCACCTCCCCCTTTGC
  CTGGGGCTACTGCCATCCCCCCACCTCCCCCTTTGCCTGGGGCTACTGCCATCCCCCCACCTCCCCCTTT
  GCCTGGAGGTACAGGTATACCACCACCACCTCCTCCTTTGCCTGGAAGTGTTGGCGTTCCCCCACCCCCT
  CCCTTGCCTGGAGGACCAGGACTGCCTCCTCCCCCTCCCCCTTTTCCTGGAGCACCTGGCATTCCTCCAC
  CTCCACCTGGTATGGGCGTGCCTCCACCTCCCCCCTTTGGATTTGGGGTTCCTGCGGCCCCAGTTCTGCC
  ATTTGGATTAACCCCCAAAAAAGTTTATAAGCCAGAGGTGCAGCTCCGGAGGCCAAACTGGTCCAAGTTT
  GTGGCTGAGGACCTTTCCCAGGACTGCTTCTGGACAAAGGTGAAGGAGGACCGCTTTGAGAACAATGAAC
  TTTTTGCCAAACTTACCCTTGCCTTCTCCGCCCAGACCAAGACTTCTAAAGCCAAGAAGGATCAAGAAGG
  TGGAGAAGAAAAGAAATCTGTTCAAAAGAAGAAAGTAAAAGAGCTGAAAGTGCTGGATTCAAAGACAGCG
  CAGAATCTCTCAATCTTTTTGGGTTCATTCCGCATGCCCTATCAAGAGATAAAGAACGTTATCCTGGAGG
  TGAATGAGGCTGTTCTCACAGAGTCTATGATCCAGAACCTCATTAAACAGATGCCAGAGCCAGAGCAGCT
  AAAGATGCTCTCTGAACTGAAGGAGGAGTACGATGATCTGGCTGAGTCAGAGCAGTTTGGTGTGGTGATG
  GGCACAGTGCCCCGCCTTCGGCCTCGCCTCAACGCCATCCTCTTCAAGCTACAGTTCAGTGAGCAAGTTG
  AGAACATCAAGCCAGAGATCGTGTCTGTCACCGCCGCATGCGAAGAGCTGCGTAAGAGTGAGAACTTCTC
  CAGCCTCCTGGAGCTCACACTGCTGGTCGGAAACTATATGAATGCGGGCTCCAGGAATGCTGGTGCTTTC
  GGCTTCAATATCAGCTTCCTTTGTAAGCTTCGAGACACCAAGTCTGCAGATCAGAAGATGACTCTGTTGC
  ATTTCTTGGCTGAGTTATGTGAGAATGACCACCCCGAAGTCCTCAAGTTTCCTGATGAGCTTGCCCATGT
  AGAGAAAGCCAGCAGAGTCTCTGCTGAGAACCTGCAGAAGAGCTTAGATCAGATGAAGAAGCAGATTGCG
  GACGTGGAGCGCGATGTTCAGAATTTCCCAGCTGCCACTGACGAGAAGGACAAGTTTGTTGAGAAGATGA
  CCAGCTTTGTGAAGGATGCACAGGAACAGTATAACAAACTACGGATGATGCACTCCAACATGGAGACCCT
  CTATAAGGAGCTAGGTGACTACTTCGTCTTTGACCCTAAGAAGTTGTCTGTAGAGGAATTCTTTATGGAT
  CTGCACAACTTTAGGAATATGTTTTTGCAAGCAGTCAAGGAAAACCAGAAGCGCCGGGAAACAGAAGAAA
  AGATGCGGAGAGCAAAATTAGCCAAGGAGAAGGCAGAAAAAGAGCGACTGGAGAAGCAGCAGAAGCGCGA
  GCAGCTCATCGACATGAACGCAGAGGGGGATGAGACAGGTGTGATGGACAGTCTTCTAGAAGCTCTGCAG
  TCAGGGGCAGCATTCCGACGGAAGAGAGGGCCCCGGCAGGTCAACAGGAAGGCTGGGTGTGCAGTCACAT
  CTCTGCTAGCCTCGGAGCTGACCAAGGATGATGCCATGGCTCCTGGTCCTGTTAAGGTACCCAAGAAAAG
  TGAAGGAGTCCCCACAATCCTGGAAGAAGCCAAGGAGCTGGTTGGCCGTGCAAGCTAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_007858
• ORF Size: 3768 bp
• Insert Size: 3768
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_007858.3, NP_031884.1
• RefSeq Size: 5633
• RefSeq ORF: 3768
• Locus ID: 13367
• Gene Summary: This gene encodes a member of the formin family of proteins that play important roles in cytoskeletal rearragnement by nucleation of actin filaments. Mice lacking the encoded protein develop age-dependent myeloproliferative defects resembling human myeloproliferative syndrome and myelodysplastic syndromes. Trafficking of T lymphocytes to secondary lymphoid organs and egression of thymocytes from the thymus are impaired in these animals. Lack of the encoded protein in T lymphocytes and thymocytes also reduces chemotaxis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2016]
  Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region compared to variant 1. It encodes isoform 2 which is shorter, compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.