Pax6 (NM_001244200) Mouse Untagged Clone

CAT#: MC227695

Pax6 (untagged) - Mouse paired box 6 (Pax6), transcript variant 2


  "NM_001244200" in other vectors (1)

Reconstitution Protocol

USD 430.00

2 Weeks*

Size
    • 10 ug

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Specifications

Product Data
Type Mouse Untagged Clone
Tag Tag Free
Symbol Pax6
Synonyms 1500038E17Rik; AEY11; Dey; Gsfaey11; Pax-6; Sey
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>MC227695 representing NM_001244200
Red=Cloning site Blue=ORF Orange=Stop codon

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGCAGAACAGTCACAGCGGAGTGAATCAGCTTGGTGGTGTCTTTGTCAACGGGCGGCCACTGCCGGACT
CCACCCGGCAGAAGATCGTAGAGCTAGCTCACAGCGGGGCCCGGCCGTGCGACATTTCCCGAATTCTGCA
GACCCATGCAGATGCAAAAGTCCAGGTGCTGGACAATGAAAACGTATCCAACGGTTGTGTGAGTAAAATT
CTGGGCAGGTATTACGAGACTGGCTCCATCAGACCCAGGGCAATCGGAGGGAGTAAGCCAAGAGTGGCGA
CTCCAGAAGTTGTAAGCAAAATAGCCCAGTATAAACGGGAGTGCCCTTCCATCTTTGCTTGGGAAATCCG
AGACAGATTATTATCCGAGGGGGTCTGTACCAACGATAACATACCCAGTGTGTCATCAATAAACAGAGTT
CTTCGCAACCTGGCTAGCGAAAAGCAACAGATGGGCGCAGACGGCATGTATGATAAACTAAGGATGTTGA
ACGGGCAGACCGGAAGCTGGGGCACACGCCCTGGTTGGTATCCCGGGACTTCAGTACCAGGGCAACCCAC
GCAAGATGGCTGCCAGCAACAGGAAGGAGGGGGAGAGAACACCAACTCCATCAGTTCTAACGGAGAAGAC
TCGGATGAAGCTCAGATGCGACTTCAGCTGAAGCGGAAGCTGCAAAGAAATAGAACATCTTTTACCCAAG
AGCAGATTGAGGCTCTGGAGAAAGAGTTTGAGAGGACCCATTATCCAGATGTGTTTGCCCGGGAAAGACT
AGCAGCCAAAATAGATCTACCTGAAGCAAGAATACAGGTATGGTTTTCTAATCGAAGGGCCAAATGGAGA
AGAGAAGAGAAACTGAGGAACCAGAGAAGACAGGCCAGCAACACTCCTAGTCACATTCCTATCAGCAGCA
GCTTCAGTACCAGTGTCTACCAGCCAATCCCACAGCCCACCACACCTGTCTCCTCCTTCACATCAGGTTC
CATGTTGGGCCGAACAGACACCGCCCTCACCAACACGTACAGTGCTTTGCCACCCATGCCCAGCTTCACC
ATGGCAAACAACCTGCCTATGCAACCCCCAGTCCCCAGTCAGACCTCCTCATACTCGTGCATGCTGCCCA
CCAGCCCGTCAGTGAATGGGCGGAGTTATGATACCTACACCCCTCCGCACATGCAAACACACATGAACAG
TCAGCCCATGGGCACCTCGGGGACCACTTCAACAGGACTCATTTCACCTGGAGTGTCAGTTCCCGTCCAA
GTTCCCGGGAGTGAACCTGACATGTCTCAGTACTGGCCTCGATTACAGTAA


ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites SgfI-MluI     
ACCN NM_001244200
ORF Size 1311 bp
Insert Size 1311
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This clone expresses the complete ORF with c-terminal tags of Myc-DDK.
Reference Data
RefSeq NM_001244200.2, NP_001231129.1
RefSeq Size 3726
RefSeq ORF 1311
Locus ID 18508
Gene Summary This gene encodes a homeobox-containing protein that functions as a regulator of transcription. It plays a key role in the development of neural tissues, particularly the eye. Activity of this protein is also required for expression of glucagon in the pancreas. This gene is regulated by multiple enhancers located up to tens or hundreds of kilobases upstream and downstream of the transcription start sites. Mutations in this gene or deletion of these regulatory elements results in severe defects in eye development. Alternative splicing and the use of alternative promoters results in multiple transcript variants, some of which encode proteins that lack the N-terminal paired domain. [provided by RefSeq, Jul 2015]
Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. It initiates from the P1 promoter. Variants 1, 2, and 3 encode the same protein (isoform 1, also known as 5a).

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