F10 (NM_001242368) Mouse Untagged Clone

CAT#: MC228005

F10 (untagged) - Mouse coagulation factor X (F10), transcript variant 1

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: F10
• Synonyms: Cf10; fX
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC228005 representing NM_001242368
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCCTGTCACAGCCACTGCCGTCCTTGACCACACCATGGGGAGCCCGGTGCAACTCAGCCTGCTCTGTG
  TTGTCCTGGCCAGCCTCCTGCTCCCTGGGAAAGGTGTGTTTATTAACCGGGAACGTGCCAACAATGTCCT
  GGCGAGGACTCGGAGGGCAAACTCATTTTTTGAAGAGTTCAAGAAAGGAAATCTGGAAAGAGAGTGTATG
  GAAGAAATTTGTTCTTATGAAGAGGTCCGTGAAATCTTCGAGGACGACGAGAAGACGAAAGAATACTGGA
  CCAAATATAAAGACGGCGACCAGTGTGAAAGCAGCCCTTGCCAGAACCAAGGAGCGTGTCGAGATGGCAT
  CGGGGGTTACACGTGCACCTGCTCGGAGGGATTTGAAGGCAAAAACTGTGAGCTCTTTGTTCGGAAACTC
  TGCCGCCTAGACAACGGAGACTGTGACCAGTTCTGCAGAGAAGAGCAGAACTCAGTGGTGTGCTCCTGCG
  CCAGCGGTTACTTCCTGGGTAATGATGGCAAGTCTTGCATCTCCACAGCTCCCTTCCCCTGTGGAAAAAT
  CACTACAGGACGTAGGAAGAGGTCTGTGGCCCTAAACACCAGCGACAGTGAGCTTGACCTTGAAGACGCC
  CTGCTTGATGAGGATTTCCTGTCCCCTACGGAGAATCCTATTGAACTGCTCAACCTCAACGAGACACAGC
  CTGAGAGGAGCAGCGATGACCTTGTTCGGATTGTGGGTGGCCGGGAATGCAAGGATGGAGAATGTCCCTG
  GCAGGCTCTGCTCATTAACGAAGACAATGAAGGGTTCTGTGGGGGCACCATCTTGAATGAGTTCTACATC
  CTCACTGCTGCCCACTGTCTCCATCAGGCCAGGCGATTCAAGGTGAGGGTAGGTGATCGGAACACAGAGA
  AGGAAGAAGGCAACGAGATGGTGCACGAGGTGGACGTGGTCATTAAGCACAACAAGTTTCAGAGGGACAC
  CTACGACTATGATATCGCCGTGCTGAGGCTGAAGACTCCCATCACGTTCCGGATGAACGTGGCCCCTGCC
  TGCCTGCCTCAGAAAGACTGGGCCGAGTCCACACTGATGACACAGAAGACGGGCATCGTGAGCGGGTTTG
  GACGCACGCATGAGAAGGGCCGCCAGTCGAACATCCTGAAGATGCTGGAGGTACCCTACGTGGATCGCAA
  CACCTGCAAGCTCTCCACCAGCTTCAGCATCACACAGAATATGTTCTGTGCGGGCTATGAGGCCAAGTTA
  GAGGATGCCTGCCAGGGGGACAGTGGTGGCCCCCATGTCACACGGTTCAAAAATACCTACTATGTGACCG
  GCATTGTCAGCTGGGGAGAGGGGTGTGCAAGGAAAGGGAAATATGGCATCTACACAAAGGTCACGACCTT
  CCTCAAGTGGATTGACAGGTCCATGAAAGCCAGGGTGGGACCCACAGCCGAGACCCCAAGGACAGCAGGT
  CCGCCCAATTAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001242368
• ORF Size: 1482 bp
• Insert Size: 1482
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This clone expresses the complete ORF with c-terminal tags of Myc-DDK.

Reference Data

• RefSeq: NM_001242368.1, NP_001229297.1
• RefSeq Size: 2693
• RefSeq ORF: 1482
• Locus ID: 14058
• Gene Summary: This gene encodes factor X, a component of both the intrinsic and extrinsic blood coagulation pathways. The encoded protein is a zymogen that undergoes further processing in a vitamin K-dependent manner to generate mature factor X, a heterodimer comprised of disulfide-linked heavy and light chains. The mature factor X is proteolytically activated either by factor IXa (intrinsic pathway) or factor VIIa (extrinsic pathway) to form factor Xa serine endopeptidase. Activated factor Xa catalyzes the conversion of prothrombin to thrombin. A complete lack of the encoded protein is fatal to mice. A severe deficiency of the encoded protein in mice causes age-dependent iron deposition and cardiac fibrosis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.