Trpc6 (NM_001282086) Mouse Untagged Clone

CAT#: MC229048

Trpc6 (untagged) - Mouse transient receptor potential cation channel, subfamily C, member 6 (Trpc6), transcript variant 2

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Trpc6
• Synonyms: AV025995; LLHWJM002; LLHWJM003; LLHWJM004; mtrp6; TRP-6; Trrp6
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC229048 representing NM_001282086
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAGCCAGAGCCCGAGGTTCGTGACCCGGAGGGGCGGCTCTCTAAAGGCTGCCCCTGGAGCCGGCACCC
  GGCGCAACGAGAGCCAGGACTATTTGCTGATGGACGAGCTGGGAGACGACGGCTACCCGCAGCTCCCGCT
  GCCACCGTATGGCTACTACCCCAGCTTCCGGGGTAATGAAAACAGACTGACTCACCGGCGGCAGACGATT
  CTTCGTGAGAAGGGAAGAAGGTTAGCTAATCGAGGACCAGCATACATGTTTAATGATCATTCAACAAGCC
  TGTCTATTGAGGAAGAACGCTTTCTAGATGCAGCTGAATATGGCAACATCCCAGTGGTGCGGAAGATGCT
  AGAAGAGTGTCATTCCCTCAATGTTAACTGTGTGGATTACATGGGCCAGAATGCCCTACAGCTGGCTGTG
  GCCAATGAGCACTTGGAAATCACAGAGCTGCTACTCAAGAAGGAAAACTTGTCTCGAGTTGGGGATGCTT
  TACTTTTAGCCATTAGTAAAGGTTATGTACGGATTGTGGAGGCAATCCTCAACCATCCAGCTTTTGCTGA
  AGGCAAAAGGTTAGCGACAAGCCCCAGCCAGTCTGAACTTCAGCAAGATGACTTTTATGCCTATGATGAA
  GATGGGACGCGGTTCTCCCATGATGTGACCCCAATCATTCTCGCTGCACATTGCCAGGAATATGAAATTG
  TGCATACCCTCCTGAGAAAGGGTGCCCGGATTGAGCGGCCTCATGATTACTTCTGCAAGTGTACAGAATG
  CAGCCAGAAGCAGAAGCATGATTCCTTCAGCCACTCTAGATCCAGGATCAATGCATACAAAGGTCTGGCA
  AGTCCAGCATACCTGTCATTGTCCAGTGAAGATCCAGTCATGACTGCTTTAGAACTTAGCAATGAGCTGG
  CAGTGCTTGCCAACATTGAGAAAGAGTTCAAGAATGACTACAGGAAGCTGTCTATGCAGTGCAAGGATTT
  CGTTGTTGGTCTCTTGGACCTCTGCAGAAACACAGAGGAAGTGGAGGCCATCCTGAATGGGGATGCAGAG
  ACTCGCCAGCCCGGGGACTTCGGCCGTCCAAATCTCAGCCGTTTAAAACTTGCTATTAAGTATGAAGTAA
  AAAAATTTGTGGCTCATCCAAACTGTCAGCAACAGCTCCTGTCCATATGGTATGAGAACCTCTCTGGTTT
  ACGGCAGCAGACCATGGCAGTGAAGTTCCTCGTGGTCCTTGCTGTTGCCATTGGATTGCCCTTCCTGGCT
  CTCATATACTGGTGTGCTCCTTGCAGCAAGATGGGGAAGATATTGCGAGGACCGTTCATGAAGTTTGTAG
  CACACGCAGCCTCCTTCACCATTTTCCTGGGGCTGCTCGTCATGAATGCAGCTGACAGATTTGAAGGCAC
  CAAGCTCCTCCCTAATGAAACCAGCACAGATAATGCAAGGCAGCTGTTCAGGATGAAAACATCCTGTTTC
  TCATGGATGGAGATGCTCATTATATCCTGGGTAATAGCCAGGATAAAGTGGGACCCTACTGATCCTCAGA
  TCATCTCTGAAGGTCTTTATGCAATCGCTGTGGTTTTAAGTTTCTCCAGAATAGCTTACATTTTACCAGC
  AAATGAAAGCTTTGGACCTCTGCAGATTTCACTTGGAAGAACAGTGAAAGATATCTTCAAATTCATGGTC
  ATATTCATCATGGTGTTTGTAGCCTTTATGATTGGAATGTTCAACCTTTACTCCTACTACATTGGCGCAA
  AACAGAATGAAGCATTCACAACAGTTGAGGAAAGTTTTAAGACACTGTTCTGGGCTATCTTTGGTCTTTC
  TGAAGTGAAGTCAGTGGTCATTAACTACAATCACAAGTTCATTGAAAACATCGGCTACGTTCTGTATGGT
  GTCTATAATGTCACAATGGTCATTGTTTTGCTAAATATGTTAATTGCGATGATCAATAGTTCATTCCAGG
  AAATTGAGGATGATGCGGACGTGGAGTGGAAGTTTGCAAGGGCCAAATTGTGGTTTTCCTACTTTGAGGA
  GGGGAGAACACTTCCTGTCCCCTTCAATCTTGTACCAAGTCCAAAATCCTTGCTTTATCTCCTATTGAAA
  TTTAAGAAATGGATGTGTGAGCTCATCCAGGGTCAAAAGCAAGGCTTCCAAGAAGATGCAGAGATGAACA
  AGAGAAATGAAGAAAAGAAATTTGGAATTTCAGGAAGTCACGAAGACCTTTCAAAATTTTCACTTGACAA
  AAATCAGTTGGCACACAACAAACAATCAAGTACAAGGAGCTCAGAAGATTATCATTTAAATAGTTTCAGT
  AACCCTCCAAGACAATATCAGAAAATCATGAAGAGACTCATTAAAAGATATGTATTGCAGGCCCAGATTG
  ATAAGGAGAGCGATGAGGTGAATGAAGGGGAATTGAAGGAAATTAAGCAAGACATCTCAAGTCTCCGTTA
  TGAACTCCTTGAAGAGAAATCACAGAACACAGAAGACCTAGCAGAGCTCATTAGAAAACTCGGGGAGAGA
  CTGTCGTTAGAGCCAAAGCTGGAGGAAAGCCGCAGATAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001282086
• ORF Size: 2559 bp
• Insert Size: 2559
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This clone expresses the complete ORF with c-terminal tags of Myc-DDK.

Reference Data

• RefSeq: NM_001282086.1, NP_001269015.1
• RefSeq Size: 3025
• RefSeq ORF: 2559
• Locus ID: 22068
• Gene Summary: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C. Seems not to be activated by intracellular calcium store depletion. [UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (2) lacks an in-frame exon in the central coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1.