C1qc (NM_007574) Mouse Tagged ORF Clone

CAT#: MG203092

C1qc (GFP-tagged) - Mouse complement component 1, q subcomponent, C chain (C1qc)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: TurboGFP
• Symbol: C1qc
• Synonyms: Adib; AI385742; C1qg; Ciqc
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MG203092 representing NM_007574
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGTCGTTGGACCCAGTTGCCAGCCTCCATGTGGACTTTGCCTGCTGCTGCTGTTTCTTCTGGCCCTAC
  CACTCAGGAGCCAGGCCAGCGCTGGCTGCTATGGGATCCCAGGGATGCCAGGCATGCCGGGGGCCCCTGG
  GAAGGACGGGCATGATGGACTCCAGGGGCCCAAGGGAGAGCCAGGAATCCCAGCCGTCCCTGGGACCCGA
  GGACCCAAGGGTCAGAAGGGCGAGCCTGGCATGCCTGGCCACCGTGGGAAAAATGGCCCTAGGGGGACCT
  CAGGGTTGCCAGGGGACCCAGGCCCCAGGGGGCCTCCGGGGGAGCCAGGTGTGGAGGGCCGATACAAACA
  GAAGCACCAGTCGGTATTCACAGTCACCCGGCAGACCACCCAGTACCCAGAGGCCAACGCCCTCGTCAGG
  TTCAACTCTGTGGTCACCAACCCTCAGGGGCATTACAACCCAAGCACAGGGAAGTTCACCTGTGAAGTGC
  CGGGCCTCTACTACTTCGTCTACTACACATCGCATACGGCCAACCTGTGCGTGCACCTGAACCTCAACCT
  TGCCAGGGTGGCCAGCTTCTGCGACCACATGTTCAACAGCAAGCAGGTCAGCTCCGGAGGAGTCCTCCTG
  CGGCTCCAGAGGGGCGACGAGGTGTGGCTATCAGTCAATGACTACAATGGCATGGTGGGCATAGAGGGCT
  CCAACAGCGTCTTCTCTGGTTTCCTACTGTTTCCCGAC
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >MG203092 representing NM_007574
  Red=Cloning site Green=Tags(s)
  
  MVVGPSCQPPCGLCLLLLFLLALPLRSQASAGCYGIPGMPGMPGAPGKDGHDGLQGPKGEPGIPAVPGTR
  GPKGQKGEPGMPGHRGKNGPRGTSGLPGDPGPRGPPGEPGVEGRYKQKHQSVFTVTRQTTQYPEANALVR
  FNSVVTNPQGHYNPSTGKFTCEVPGLYYFVYYTSHTANLCVHLNLNLARVASFCDHMFNSKQVSSGGVLL
  RLQRGDEVWLSVNDYNGMVGIEGSNSVFSGFLLFPD
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_007574
• ORF Size: 738 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_007574.2, NP_031600.2
• RefSeq Size: 1063
• RefSeq ORF: 741
• Locus ID: 12262
• Gene Summary: C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. [UniProtKB/Swiss-Prot Function]