Mmp2 (NM_008610) Mouse Tagged ORF Clone

CAT#: MG209857

Mmp2 (GFP-tagged) - Mouse matrix metallopeptidase 2 (Mmp2)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: TurboGFP
• Symbol: Mmp2
• Synonyms: Clg4a; GelA; MMP-2
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MG209857 representing NM_008610
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGAGGCACGAGTGGCCTGGGGAGCGCTGGCCGGACCTCTGCGGGTTCTCTGCGTCCTGTGCTGCCTGT
  TGGGCCGCGCCATCGCTGCACCATCGCCCATCATCAAGTTCCCCGGCGATGTCGCCCCTAAAACAGACAA
  AGAGTTGGCAGTGCAATACCTGAACACTTTCTATGGCTGCCCCAAGGAGAGTTGCAACCTCTTTGTGCTG
  AAAGATACCCTCAAGAAGATGCAGAAGTTCTTTGGGCTGCCCCAGACAGGTGACCTTGACCAGAACACCA
  TCGAGACCATGCGGAAGCCAAGATGTGGCAACCCAGATGTGGCCAACTACAACTTCTTCCCCCGCAAGCC
  CAAGTGGGACAAGAACCAGATCACATACAGGATCATTGGTTACACACCTGACCTGGACCCTGAAACCGTG
  GATGATGCTTTTGCTCGGGCCTTAAAAGTATGGAGCGACGTCACTCCGCTGCGCTTTTCTCGAATCCATG
  ATGGGGAGGCTGACATCATGATCAACTTTGGACGCTGGGAGCATGGAGATGGATACCCATTTGATGGCAA
  GGATGGACTCCTGGCACATGCCTTTGCCCCGGGCACTGGTGTTGGGGGAGATTCTCACTTTGATGATGAT
  GAGCTGTGGACCCTGGGAGAAGGACAAGTGGTCCGCGTAAAGTATGGGAACGCTGATGGCGAGTACTGCA
  AGTTCCCCTTCCTGTTCAACGGTCGGGAATACAGCAGCTGTACAGACACTGGTCGCAGTGATGGCTTCCT
  CTGGTGCTCCACCACATACAACTTTGAGAAGGATGGCAAGTATGGCTTCTGCCCCCATGAAGCCTTGTTT
  ACCATGGGTGGCAATGCAGATGGACAGCCCTGCAAGTTCCCGTTCCGCTTCCAGGGCACCTCCTACAACA
  GCTGTACCACCGAGGGCCGCACCGATGGCTACCGCTGGTGTGGCACCACCGAGGACTATGACCGGGATAA
  GAAGTATGGATTCTGTCCCGAGACCGCTATGTCCACTGTGGGTGGAAATTCAGAAGGTGCCCCATGTGTC
  TTCCCCTTCACTTTCCTGGGCAACAAGTATGAGAGCTGCACCAGCGCCGGCCGCAACGATGGCAAGGTGT
  GGTGTGCGACCACAACCAACTACGATGATGACCGGAAGTGGGGCTTCTGTCCTGACCAAGGATATAGCCT
  ATTCCTCGTGGCAGCCCATGAGTTCGGCCATGCCATGGGGCTGGAACACTCTCAGGACCCTGGAGCTCTG
  ATGGCCCCGATCTACACCTACACCAAGAACTTCCGATTATCCCATGATGACATCAAGGGGATCCAGGAGC
  TCTATGGGCCCTCCCCCGATGCTGATACTGACACTGGTACTGGCCCCACACCAACACTGGGACCTGTCAC
  TCCGGAGATCTGCAAACAGGACATTGTCTTTGATGGCATCGCTCAGATCCGTGGTGAGATCTTCTTCTTC
  AAGGACCGGTTTATTTGGCGGACAGTGACACCACGTGACAAGCCCACAGGTCCCTTGCTGGTGGCCACAT
  TCTGGCCTGAGCTCCCAGAAAAGATTGACGCTGTGTATGAGGCCCCACAGGAGGAGAAGGCTGTGTTCTT
  CGCAGGGAATGAGTACTGGGTCTATTCTGCTAGTACTCTGGAGCGAGGATACCCCAAGCCACTGACCAGC
  CTGGGGTTGCCCCCTGATGTCCAGCAAGTAGATGCTGCCTTTAACTGGAGTAAGAACAAGAAGACATACA
  TCTTTGCAGGAGACAAGTTCTGGAGATACAATGAAGTGAAGAAGAAAATGGACCCCGGTTTCCCTAAGCT
  CATCGCAGACTCCTGGAATGCCATCCCTGATAACCTGGATGCCGTCGTGGACCTGCAGGGTGGTGGTCAT
  AGCTACTTCTTCAAGGGTGCTTATTACCTGAAGCTGGAGAACCAAAGTCTCAAGAGCGTGAAGTTTGGAA
  GCATCAAATCAGACTGGCTGGGCTGC
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >MG209857 representing NM_008610
  Red=Cloning site Green=Tags(s)
  
  MEARVAWGALAGPLRVLCVLCCLLGRAIAAPSPIIKFPGDVAPKTDKELAVQYLNTFYGCPKESCNLFVL
  KDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETV
  DDAFARALKVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDD
  ELWTLGEGQVVRVKYGNADGEYCKFPFLFNGREYSSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALF
  TMGGNADGQPCKFPFRFQGTSYNSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCV
  FPFTFLGNKYESCTSAGRNDGKVWCATTTNYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGAL
  MAPIYTYTKNFRLSHDDIKGIQELYGPSPDADTDTGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFF
  KDRFIWRTVTPRDKPTGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWVYSASTLERGYPKPLTS
  LGLPPDVQQVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADSWNAIPDNLDAVVDLQGGGH
  SYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_008610
• ORF Size: 1986 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_008610.2, NP_032636.1
• RefSeq Size: 3070
• RefSeq ORF: 1989
• Locus ID: 17390
• Gene Summary: This gene encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. The encoded preproprotein undergoes proteolytic processing to generate a mature, zinc-dependent endopeptidase enzyme that hydrolyzes collagens, gelatins, laminin, fibronectin and elastin. Mice lacking the encoded protein exhibit suppressed angiogenesis and attenuated features of human multicentric osteolysis with arthritis including abnormal skeletal and craniofacial development. [provided by RefSeq, Feb 2016]