Igfbp3 (NM_008343) Mouse Tagged ORF Clone

CAT#: MR204018L3

Lenti ORF clone of Igfbp3 (Myc-DDK-tagged) - Mouse insulin-like growth factor binding protein 3 (Igfbp3)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Igfbp3
• Synonyms: AI649005; IGFBP-3; IGgfbp3
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR204018).
• Restriction Sites: SgfI-NotI Cloning Scheme for this gene
• ACCN: NM_008343
• ORF Size: 879 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_008343.2, NP_032369.2
• RefSeq Size: 2456
• RefSeq ORF: 879
• Locus ID: 16009
• Gene Summary: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R. [UniProtKB/Swiss-Prot Function]