Kcnj5 (NM_010605) Mouse Tagged ORF Clone

CAT#: MR226110L3

Lenti ORF clone of Kcnj5 (Myc-DDK-tagged) - Mouse potassium inwardly-rectifying channel, subfamily J, member 5 (Kcnj5)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Kcnj5
• Synonyms: CIR; GIRK4; KATP-1; Kir3.4
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR226110).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_010605
• ORF Size: 1257 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_010605.4, NP_034735.3
• RefSeq Size: 4496
• RefSeq ORF: 1260
• Locus ID: 16521
• Gene Summary: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium. [UniProtKB/Swiss-Prot Function]