ITM2B (NM_021999) Human Tagged ORF Clone
CAT#: RC202377L3
- LentiORF®
Lenti ORF clone of Human integral membrane protein 2B (ITM2B), Myc-DDK-tagged
"NM_021999" in other vectors (7)
Product Images
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | ITM2B |
Synonyms | ABRI; BRI; BRI2; BRICD2B; E3-16; E25B; FBD; imBRI2; RDGCA |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC202377).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_021999 |
ORF Size | 798 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_021999.2, NP_068839.1 |
RefSeq Size | 1896 |
RefSeq ORF | 801 |
Locus ID | 9445 |
Domains | BRICHOS |
Protein Families | Druggable Genome, Transmembrane |
MW | 30.4 kDa |
Gene Summary | Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia. [provided by RefSeq, Oct 2009] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC108808 | ITM2B (untagged)-Human integral membrane protein 2B (ITM2B) |
USD 310.00 |
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SC322363 | ITM2B (untagged)-Human integral membrane protein 2B (ITM2B) |
USD 310.00 |
|
RC202377 | ITM2B (Myc-DDK-tagged)-Human integral membrane protein 2B (ITM2B) |
USD 420.00 |
|
RG202377 | ITM2B (GFP-tagged) - Human integral membrane protein 2B (ITM2B) |
USD 460.00 |
|
RC202377L1 | Lenti ORF clone of Human integral membrane protein 2B (ITM2B), Myc-DDK-tagged |
USD 768.00 |
|
RC202377L2 | Lenti ORF clone of Human integral membrane protein 2B (ITM2B), mGFP tagged |
USD 620.00 |
|
RC202377L4 | Lenti ORF clone of Human integral membrane protein 2B (ITM2B), mGFP tagged |
USD 620.00 |
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