EFEMP2 (NM_016938) Human Tagged ORF Clone

CAT#: RC203726L3

Lenti ORF clone of Human EGF containing fibulin-like extracellular matrix protein 2 (EFEMP2), transcript variant 1, Myc-DDK-tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: EFEMP2
• Synonyms: ARCL1B; FBLN4; MBP1; UPH1
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC203726).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_016938
• ORF Size: 1329 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_016938.2, NP_058634.1, NP_058634.2
• RefSeq Size: 2096
• RefSeq ORF: 1332
• Locus ID: 30008
• Domains: EGF_CA, EGF, EGF
• Protein Families: Druggable Genome, Secreted Protein
• MW: 49.4 kDa
• Gene Summary: A large number of extracellular matrix proteins have been found to contain variations of the epidermal growth factor (EGF) domain and have been implicated in functions as diverse as blood coagulation, activation of complement and determination of cell fate during development. The protein encoded by this gene contains four EGF2 domains and six calcium-binding EGF2 domains. This gene is necessary for elastic fiber formation and connective tissue development. Defects in this gene are cause of an autosomal recessive cutis laxa syndrome. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jan 2011]