PARL (NM_018622) Human Tagged ORF Clone
CAT#: RC204096L3
- LentiORF®
Lenti ORF clone of Human presenilin associated, rhomboid-like (PARL), nuclear gene encoding mitochondrial protein, transcript variant 1, Myc-DDK-tagged
"NM_018622" in other vectors (6)
Product Images
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | PARL |
Synonyms | PRO2207; PSARL; PSARL1; PSENIP2; RHBDS1 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC204096).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_018622 |
ORF Size | 1137 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_018622.5, NP_061092.3 |
RefSeq Size | 1423 |
RefSeq ORF | 1140 |
Locus ID | 55486 |
Domains | Rhomboid |
Protein Families | Protease, Transmembrane |
MW | 42.2 kDa |
Gene Summary | This gene encodes a member of the rhomboid family of intramembrane serine proteases that is localized to the inner mitochondrial membrane. The encoded protein regulates mitochondrial remodeling and apoptosis through regulated substrate proteolysis. Proteolytic processing of the encoded protein results in the release of a small peptide, P-beta, which may transit to the nucleus. Mutations in this gene may be associated with Parkinson's disease. [provided by RefSeq, May 2016] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC108782 | PARL (untagged)-Human presenilin associated, rhomboid-like (PARL), nuclear gene encoding mitochondrial protein, transcript variant 1 |
USD 760.00 |
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RC204096 | PARL (Myc-DDK-tagged)-Human presenilin associated, rhomboid-like (PARL), nuclear gene encoding mitochondrial protein, transcript variant 1 |
USD 420.00 |
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RG204096 | PARL (GFP-tagged) - Human presenilin associated, rhomboid-like (PARL), nuclear gene encoding mitochondrial protein, transcript variant 1 |
USD 460.00 |
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RC204096L1 | Lenti ORF clone of Human presenilin associated, rhomboid-like (PARL), nuclear gene encoding mitochondrial protein, transcript variant 1, Myc-DDK-tagged |
USD 768.00 |
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RC204096L2 | Lenti ORF clone of Human presenilin associated, rhomboid-like (PARL), nuclear gene encoding mitochondrial protein, transcript variant 1, mGFP tagged |
USD 620.00 |
|
RC204096L4 | Lenti ORF clone of Human presenilin associated, rhomboid-like (PARL), nuclear gene encoding mitochondrial protein, transcript variant 1, mGFP tagged |
USD 620.00 |
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