ERLIN1 (NM_006459) Human Tagged ORF Clone

CAT#: RC205137L3

Lenti ORF clone of Human ER lipid raft associated 1 (ERLIN1), Myc-DDK-tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: ERLIN1
• Synonyms: C10orf69; Erlin-1; KE04; KEO4; SPFH1; SPG62
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC205137).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_006459
• ORF Size: 1038 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_006459.3, NP_006450.1, NP_006450.2
• RefSeq Size: 3450
• RefSeq ORF: 1047
• Locus ID: 10613
• Domains: Band_7
• Protein Families: Transmembrane
• MW: 38.9 kDa
• Gene Summary: The protein encoded by this gene is part of a protein complex that mediates degradation of inositol 1,4,5-trisphosphate receptors in the endoplasmic reticulum. The encoded protein also binds cholesterol and regulates the SREBP signaling pathway, which promotes cellular cholesterol homeostasis. Defects in this gene have been associated with spastic paraplegia 62. [provided by RefSeq, Dec 2016]