ERLIN1 (NM_006459) Human Untagged Clone

CAT#: SC116080

ERLIN1 (untagged)-Human ER lipid raft associated 1 (ERLIN1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ERLIN1
• Synonyms: C10orf69; Erlin-1; KE04; KEO4; SPFH1; SPG62
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC116080 sequence for NM_006459 edited (data generated by NextGen Sequencing)
  ATGAATATGACTCAAGCCCGGGTTCTGGTGGCTGCAGTGGTGGGGTTGGTGGCTGTCCTG
  CTCTACGCCTCCATCCACAAGATTGAGGAGGGCCATCTGGCTGTGTACTACAGGGGAGGA
  GCTTTACTAACTAGCCCCAGTGGACCAGGCTATCATATCATGTTGCCTTTCATTACTACG
  TTCAGATCTGTGCAGACAACACTACAAACTGATGAAGTTAAAAATGTGCCTTGTGGAACA
  AGTGGTGGGGTCATGATCTATATTGACCGAATAGAAGTGGTTAATATGTTGGCTCCTTAT
  GCAGTGTTTGATATCGTGAGGAACTATACTGCAGATTATGACAAGACCTTAATCTTCAAT
  AAAATCCACCATGAGCTGAACCAGTTCTGCAGTGCCCACACACTTCAGGAAGTTTACATT
  GAATTGTTTGATCAAATAGATGAAAACCTGAAGCAAGCTCTGCAGAAAGACTTAAACCTC
  ATGGCCCCAGGTCTCACTATACAGGCTGTGCGTGTTACAAAACCCAAAATCCCAGAAGCC
  ATAAGAAGAAATTTTGAGTTAATGGAGGCTGAGAAGACAAAACTCCTTATAGCTGCACAG
  AAACAAAAGGTTGTGGAAAAAGAAGCTGAGACAGAGAGGAAAAAGGCAGTTATAGAAGCA
  GAGAAGATTGCACAAGTGGCAAAAATTCGGTTTCAGCAGAAAGTGATGGAAAAAGAAACT
  GAAAAGCGCATTTCTGAAATCGAAGATGCTGCATTCCTGGCCCGAGAGAAAGCGAAAGCA
  GATGCTGAATATTATGCTGCACACAAATATGCCACCTCAAACAAGCACAAGTTGACCCCG
  GAATATCTGGAGCTCAAAAAGTACCAGGCCGTTGCTTCTAACAGTAAGATCTATTTTGGC
  AGCAACATCCCTAACATGTTCGTGGACTCCTCATGTGCTTTGAAATATTCAGATATTAGG
  ACTGGAAGAGAAAGCTCACTCCCCTCTAAGGAGGCTCTTGAACCCTCTGGAGAGAACGTC
  ATCCAAAACAAAGAGAGCACAGGTTGA
  
  Clone variation with respect to NM_006459.3
  871 a=>g
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006459 unedited
  AGGATTTTGTAATACGACTCACTATAGGGCGGCCCGCGAATTCGCACGAGGGCTGCACGT
  GCGGGCGGGGGCGATGCGTCACTGATCGGAGGAACGAGAATGAATATGACTCAAGCCCGG
  GTTCTGGTGGCTGCAGTGGTGGGGTTGGTGGCTGTCCTGCTCTACGCCTCCATCCACAAG
  ATTGAGGAGGGCCATCTGGCTGTGTACTACAGGGGAGGAGCTTTACTAACTAGCCCCAGT
  GGACCAGGCTATCATATCATGTTGCCTTTCATTACTACGTTCAGATCTGTGCAGACAACA
  CTACAAACTGATGAAGTTAAAAATGTGCCTTGTGGAACAAGTGGTGGGGTCATGATCTAT
  ATTGACCGAATAGAAGTGGTTAATATGTTGGCTCCTTATGCAGTGTTTGATATCGTGAGG
  AACTATACTGCAGATTATGACAAGACCTTAATCTTCAATAAAATCCACCATGAGCTGAAC
  CAGTTCTGCAGTGCCCACACACTTCAGGAAGTTTACATTGAATTGTTTGATCAAATAGAT
  GAAAACCTGAAGCAAGCTCTGCAGAAAGACTTAAACCTCATGGCCCCAGGTCTCACTATA
  CAGGCTGTGCGTGTTACAAAACCCAAAATCCCAGAAGCCATAAGAAGAAATTTTGAGTTA
  ATGGAGGCTGAGAAGACAAAACTCCTTATAGCTGCACAGAAACAAAAGGTTGTGGAAAAA
  GAAGCTGAGACAGAGAGGAAAAAGGCAGTTATAGAAGCAGAGAAGATTGCACAAGTGGCA
  AANATTCGGTTTCAGCAGAAAGTGATGGAAAAAGAACTGANAGCGCATTTCTGAAATCGA
  GATGCTGCATTCCTGGCCCGAGAGAAACGAAAGCAGATGCTGAATATTATGCTGCACACA
  NATATGCCACCCTCAACAAGCACAAGNTGACCCCCGNATATCTGNAGCTCAAAAGTACCC
  AGCCCGTGCTTCTACAAGTAGATCTATTA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006459 unedited
  CAATCTAAAGTCGAGTTTTTTTTTTTTTTTTTTGATAGTAAAATAATTTTATTTAGTTTC
  TTATTTTAAAAAAGGTAGCATTTCAACATATAAATTTAGACTCAAGATTACAGTGTATAT
  TTGCCAAAAGGAACACCCCGAAAGACGGCCAGCCTCAGAGCTGAGAGGGCACAGGGAGGC
  ACACTCCTCACACATGGGAGTTTAAGCAGAAGTGCTTTAAGACTTCACAGCGGCATTTCC
  CTGTTCCTCAGCCCCGCCTCCAGGGCCATCACTTTGGGGCAACAGCTTTTGCTCATGTAA
  CTATAAAACATCTCTAGGAATGAAAGCACAGAGGTCAATGATCCAGATTTTCCACAACAA
  TCATCTGCAGCAACAATTCGACAGGTAAAGATTTTATTTTTATAATTCAAAAGTTCTTTT
  AAGGAGAACTAAAGAACACAAAATTCATTTATAAAGAGAATTTATAGAATTAAATGAGCA
  AAAATGAAAAATTATTTTCTCCATATTACAAATGCCTCTATAGGATAAGGCCCAGGGGAA
  AGACCCATTCAAATCTGGGCTTTCCTTTCCCAAATAAAGTGTTTGGCACAACCAACAAAC
  TGTCATGAGACTGACAGGCCTGACAGCTGAAAGATTTCTAGAAGTGGTCCCATGACTNTT
  TTGTTGAGCTTCAACATAGCGTACACAAGAGTTGTCTTAAACAGCTGCACANACTCAGGC
  CCGACTACGCAGCACACTGCTCCAGAAAAGTAAACTGAAGGAAAAAAGGTNCACATNGAG
  TAGGTCTCCTATGCCACAGTTAACTCTNGTGTTCTCATGGAANATAAATCACTGGCTGCC
  CAGACGTCAGTGGATCCTGNATCTCTGGGGGAGTGACAGCTGGAGAACAACTGGNATTNA
  GCATCTCTGGGCAGTGGGGAAGAGACATGATGACAGGNTGCTTCTAGTGACTTTTTGTCC
  ACTTGTGGCTCAGAAACATCTAGGACATCGGTGCTGGACAT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006459
• ORF Size: 1041 bp
• Insert Size: 3630
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006459.2, NP_006450.1
• RefSeq Size: 3115
• RefSeq ORF: 1041
• Locus ID: 10613
• Domains: Band_7
• Protein Families: Transmembrane
• Gene Summary: The protein encoded by this gene is part of a protein complex that mediates degradation of inositol 1,4,5-trisphosphate receptors in the endoplasmic reticulum. The encoded protein also binds cholesterol and regulates the SREBP signaling pathway, which promotes cellular cholesterol homeostasis. Defects in this gene have been associated with spastic paraplegia 62. [provided by RefSeq, Dec 2016]
  Transcript Variant: This variant (1) represents the longest transcript. Variants 1-6 all encode the same isoform (a).