ERLIN1 (NM_006459) Human Untagged Clone

CAT#: SC322528

ERLIN1 (untagged)-Human ER lipid raft associated 1 (ERLIN1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ERLIN1
• Synonyms: C10orf69; Erlin-1; KE04; KEO4; SPFH1; SPG62
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC322528 CGCTCCCAGGAGGAACGAGAATGAATATGACTCAAGCCCGGGTTCTGGTGGCTGCAGTGG
  TGGGGTTGGTGGCTGTCCTGCTCTACGCCTCCATCCACAAGATTGAGGAGGGCCATCTGG
  CTGTGTACTACAGGGGAGGAGCTTTACTAACTAGCCCCAGTGGACCAGGCTATCATATCA
  TGTTGCCTTTCATTACTACGTTCAGATCTGTGCAGACAACACTACAAACTGATGAAGTTA
  AAAATGTGCCTTGTGGAACAAGTGGTGGGGTCATGATCTATATTGACCGAATAGAAGTGG
  TTAATATGTTGGCTCCTTATGCAGTGTTTGATATCGTGAGGAACTATACTGCAGATTATG
  ACAAGACCTTAATCTTCAATAAAATCCACCATGAGCTGAACCAGTTCTGCAGTGCCCACA
  CACTTCAGGAAGTTTACATTGAATTGTTTGATCAAATAGATGAAAACCTGAAGCAAGCTC
  TGCAGAAAGACTTAAACCTCATGGCCCCAGGTCTCACTATACAGGCTGTGCGTGTTACAA
  AACCCAAAATCCCAGAAGCCATAAGAAGAAATTTTGAGTTAATGGAGGCTGAGAAGACAA
  AACTCCTTATAGCTGCACAGAAACAAAAGGTTGTGGAAAAAGAAGCTGAGACAGAGAGGA
  AAAAGGCAGTTATAGAAGCAGAGAAGATTGCACAAGTGGCAAAAATTCGGTTTCAGCAGA
  AAGTGATGGAAAAAGAAACTGAAAAGCGCATTTCTGAAATCGAAGATGCTGCATTCCTGG
  CCCGAGAGAAAGCGAAAGCAGATGCTGAATATTATGCTGCACACAAATATGCCACCTCAA
  ACAAGCACAAGTTGACCCCGGAATATCTGGAGCTCAAAAAGTACCAGGCCATTGCTTCTA
  ACAGTAAGATCTATTTTGGCAGCAACATCCCTAACATGTTCGTGGACTCCTCATGTGCTT
  TGAAATATTCAGATATTAGGACTGGAAGAGAAAGCTCACTCCCCTCTAAGGAGGCTCTTG
  AACCCTCTGGAGAGAACGTCATCCAAAACAAAGAGAGCACAGGTTGATGCAAGAGGTGGA
  AATGTTCTCCATATCAAGATGTGGCCCAAGGGGTTAAGTGGGAACAATCATTATACGGAC
  TCTTCAGATTTACAGAGAACTTACACTTCATCTGTTCCACCTCTCCTGCGATAGTCCTGG
  GTGCTCCACTGATTGGAGGATAGAGCCAGCTGTCTGACACACAAATGGTCTTTTCAGCCA
  CAGTCTTATCAAGTATCCTATATGTATTCCTTTCTAAACTGCTACTCATGAATGAGGAAA
  GTCTTGCTAAGATACTGCCTGCACTGGAATGTTAAACACTAAATATATAACAAGCTGTGT
  TTTCCTAAGCTGAGATCTGTTGAATAATGTTTACATTCGTCCCCCGGGGAAATGTATGCT
  CAGCCACCATTCAAGAGATGACTGAGAAGGAGATGGTAAGTTCAAGAAGACTGATTGCAC
  CTGGGACCCAGGCCCTTTCTTTGGGATCCAGTCCCAGCCTTCATCCATGTGATTAAGATC
  CAGGCCGCTGAAGTTCCCCAGGAAATGATCTTCCACTTGAGCAACCTTTTACTTGATACG
  ATTTGCACCTTTCTGTTTTCCTGCAGTCAGGGTGGTGGCCTGCAGGGACCTGAGCTTTGC
  TACCCAACCAGATTCCTCATAGAGATTCCTAATCACTAGTTTCTTGTATTCATAAACTCA
  GAGATACAGAGGGCTTGGTTTGAAGTTGGGGTGAGATGAAACCTTTGCTCTGAGCCAAAG
  CTCTGGGGCCCTGCATTCCCTGCATTGGGTTGATGACTGTCAGCATCACTGCCGCAGGCC
  ATGCTTGACTAAGGTACCTGGTTTTAGCCACAGCCACCTCCTTGTATGTTACCTTTCAGC
  TCTGGCCAAGAGTGGGACAGGGTTTTAACCACAAATAGGAGCAGCATGCAATTCCTAGTG
  ACTTGCTGCACAGTATTGTATCATAATTACAGGAAGTTTTTATTTTTAAAACTGGATCTG
  GGGTATATTCATTTGCCCCATCACCTCTGTCTAAAGGCCCAAGTCCTAGGGCTGCCATGG
  TCACAAGCACACTGATGCTCCTTAAGATTGTTTATCTGGAGCCCACATAGTGTGGAACAA
  AAAGTCACCTAGAAAGCATCCTTGGTCATCATTGTCTCCTTCCCACCTGGCCCAGAGATG
  CTTAAATCCAAGTTGTTTCTCCAGCTGTCACCTCCCCCAGGAGATCAGGATTCCACTGAC
  GTCCTGGGCAGCCAGTGAATTTAATTTTCCATGAGAAACAACAGAGTTAACCTGTGGCAT
  TAGGAGACCTACTTCATGTGGACCCTTTTTTTCCTTCAGTTTAACTTTTCTGGAGCAGTG
  TGCTGCGTAGTTCGGCCTGAGTTTGTGCAGCTTGTTAAGACAACTCTTGTGTACGCTATG
  TTGAAGCTCAACAAAAAAGTCATGGGACCACTTCTAGAAATCTTTCAGCTGTCAGGCCTG
  TCAGTCTCATGACAGTTTGTTGGTTGTGCCAAACACTTTATTTGGGAAAGGAAAGCCCAG
  ATTTGAATGGGTCTTTCCCCTGGGCCTTATCCTATAGAGGCATTTGTAATATGGAGAAAA
  TAATTTTTCATTTTTGCTCATTTAATTCTATAAATTCTCTTTATAAATGAATTTTGTGTT
  CTTTAGTTCTCCTTAAAAGAACTTTTGAATTATAAAAATAAAATCTTTACCTGTCGAATT
  GTTGCTGCAGATGATTGTTGTGGAAAATCTGGATCATTGACCTCTGTGCTTTCATTCCTA
  GAGATGTTTTATAGTTACATGAGCAAAAGCTGTTGCCCCAAAGTGATGGCCCTGGAGGCG
  GGGCTGAGGAACAGGGAAATGCCGCTGTGAAGTCTTAAAGCACTTCTGCTTAAACTCCAT
  GTGTGAGGAGTGTGCCTCCCTGTGCCCTCTCAGCTCTGAGGCTGGCCGTCTTTCGGGGTG
  TTCCTTTTGGCAAATATACACTGTAATCTTGAGTCTAAATTTATATGTTGAAATGCTACC
  TTTTTTAAAATAAGAAACTAAATAAAATTATTTTACTATCAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for SC322528 unedited
  GGCTCTTTGTATACGACTCCTATAGGGCGGCCGGCGATCGCGGCGCGCCGGTACCGGTCC
  GGAATTCCCGGGATATCGTCGACCCACGCGTCCGCGCTCCCAGGAGGAACGAGAATGAAT
  ATGACTCAAGCCCGGGTTCTGGTGGCTGCAGTGGTGGGGTTGGTGGCTGTCCTGCTCTAC
  GCCTCCATCCACAAGATTGAGGAGGGCCATCTGGCTGTGTACTACAGGGGAGGAGCTTTA
  CTAACTAGCCCCAGTGGACCAGGCTATCATATCATGTTGCCTTTCATTACTACGTTCAGA
  TCTGTGCAGACAACACTACAAACTGATGAAGTTAAAAATGTGCCTTGTGGAACAAGTGGT
  GGGGTCATGATCTATATTGACCGAATAGAAGTGGTTAATATGTTGGCTCCTTATGCAGTG
  TTTGATATCGTGAGGAACTATACTGCAGATTATGACAAGACCTTAATCTTCAATAAAATC
  CACCATGAGCTGAACCAGTTCTGCAGTGCCCACACACTTCAGGAAGTTTACATTGAATTG
  TTTGATCAAATAGATGAAAACCTGAAGCAAGCTCTGCAGAAAGACTTAAACCTCATGGCC
  CCAGGTCTCACTATACAGGCTGTGCGTGTTACAAAACCCAAAATCCCAGAAGCCATAAGA
  AGAAATTTTGAGTTAATGGAGGCTGAGAAGACAAAACTCCTTATAGCTGCACAGAAACAA
  AAGGTTGTGGAAAAAGAAGCTGAGACAGAGAGGAAAAAGGCAGTTATAGAGCAGAGAGAT
  TGCACAGTGGCAAAAATTCGGTTTCAGCAGAAGTGATGGAAAAGAACTGAAAAGCGCATT
  TTCTGAATTCGAGATGCTGCATTCTGGCCCGAGAGAAAGCGAAGCCGATGCTGAATATTT
  ATGCTGCACCAAATATGCCACCTCAACAGACAAGTGACCTGAAATTCTGGAACCTAAAAG
  GTACAGGCATTGCCTTTCTTACACGGTAGAGAATCCAAT
• Restriction Sites: Please inquire
• ACCN: NM_006459
• ORF Size: 1041 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_006459.2, NP_006450.1
• RefSeq Size: 3115
• RefSeq ORF: 1041
• Locus ID: 10613
• Domains: Band_7
• Protein Families: Transmembrane
• Gene Summary: The protein encoded by this gene is part of a protein complex that mediates degradation of inositol 1,4,5-trisphosphate receptors in the endoplasmic reticulum. The encoded protein also binds cholesterol and regulates the SREBP signaling pathway, which promotes cellular cholesterol homeostasis. Defects in this gene have been associated with spastic paraplegia 62. [provided by RefSeq, Dec 2016]
  Transcript Variant: This variant (1) represents the longest transcript. Variants 1-6 all encode the same isoform (a).