RACGAP1 (NM_013277) Human Tagged ORF Clone

CAT#: RC207542L3

Lenti ORF clone of Human Rac GTPase activating protein 1 (RACGAP1), transcript variant 1, Myc-DDK-tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: RACGAP1
• Synonyms: CYK4; HsCYK-4; ID-GAP; MgcRacGAP
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC207542).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_013277
• ORF Size: 1896 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_013277.2, NP_037409.2
• RefSeq Size: 3315
• RefSeq ORF: 1899
• Locus ID: 29127
• Domains: RhoGAP, DAG_PE-bind
• Protein Families: Druggable Genome
• MW: 71 kDa
• Gene Summary: This gene encodes a GTPase-activating protein (GAP) that is a compoment of the centralspindlin complex. This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho-mediated signals. This protein plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for this gene. There is a pseudogene for this gene on chromosome 12. [provided by RefSeq, Feb 2016]