RACGAP1 (NM_013277) Human Untagged Clone

CAT#: SC115325

RACGAP1 (untagged)-Human Rac GTPase activating protein 1 (RACGAP1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RACGAP1
• Synonyms: CYK4; HsCYK-4; ID-GAP; MgcRacGAP
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_013277 edited
  GAATTCGGCACGAGGGTGGGCGCGGCGCTGCTCTGCCGTTGGGTGAGGCGCGGAGCGAAG
  TGAAGGGTGGCCCAGGTGGGGCCAGGCTGACTGAAAAAGATGGATACTATGATGCTGAAT
  GTGCGGAATCTGTTTGAGCAGCTTGTGCGCCGGGTGGAGATTCTCAGTGAAGGAAATGAA
  GTCCAATTTATCCAGTTGGCGAAGGACTTTGAGGATTTCCGTAAAAAGTGGCAGAGGACT
  GACCATGAGCTGGGGAAATACAAGGATCTTTTGATGAAAGCAGAGACTGAGCGAAGTGCT
  CTGGATGTTAAGCTGAAGCATGCACGTAATCAGGTGGATGTAGAGATCAAACGGAGACAG
  AGAGCTGAGGCTGACTGCGAAAAGCTGGAACGACAGATTCAGCTGATTCGAGAGATGCTC
  ATGTGTGACACATCTGGCAGCATTCAACTAAGCGAGGAGCAAAAATCAGCTCTGGCTTTT
  CTCAACAGAGGCCAACCATCCAGCAGCAATGCTGGGAACAAAAGACTATCAACCATTGAT
  GAATCTGGTTCCATTTTATCAGATATCAGCTTTGACAAGACTGATGAATCACTGGATTGG
  GACTCTTCTTTGGTGAAGACTTTCAAACTGAAGAAGAGAGAAAAGAGGCGCTCTACTAGC
  CGACAGTTTGTTGATGGTCCCCCTGGACCTGTAAAGAAAACTCGTTCCATTGGCTCTGCA
  GTAGACCAGGGGAATGAATCCATAGTTGCAAAAACTACAGTGACTGTTCCCAATGATGGC
  GGGCCCATCGAAGCTGTGTCCACTATTGAGACTGTGCCATATTGGACCAGGAGCCGAAGG
  AAAACAGGTACTTTACAACCTTGGAACAGTGACTCCACCCTGAACAGCAGGCAGCTGGAG
  CCAAGAACTGAGACAGACAGTGTGGGCACGCCACAGAGTAATGGAGGGATGCGCCTGCAT
  GACTTTGTTTCTAAGACGGTTATTAAACCTGAATCCTGTGTTCCATGTGGAAAGCGGATA
  AAATTTGGCAAATTATCTCTGAAGTGTCGAGACTGTCGTGTGGTCTCTCATCCAGAATGT
  CGGGACCGCTGTCCCCTTCCCTGCATTCCTACCCTGATAGGAACACCTGTCAAGATTGGA
  GAGGGAATGCTGGCAGACTTTGTGTCCCAGACTTCTCCAATGATCCCCTCCATTGTTGTG
  CATTGTGTAAATGAGATTGAGCAAAGAGGTCTGACTGAGACAGGCCTGTATAGGATCTCT
  GGCTGTGACCGCACAGTAAAAGAGCTGAAAGAGAAATTCCTCAGAGTGAAAACTGTACCC
  CTCCTCAGCAAAGTGGATGATATCCATGCTATCTGTAGCCTTCTAAAAGACTTTCTTCGA
  AACCTCAAAGAACCTCTTCTGACCTTTCGCCTTAACAGAGCCTTTATGGAAGCAGCAGAA
  ATCACAGATGAAGACAACAGCATAGCTGCCATGTACCAAGCTGTTGGTGAACTGCCCCAG
  GCCAACAGGGACACATTAGCTTTCCTCATGATTCACTTGCAGAGAGTGGCTCAGAGTCCA
  CATACTAAAATGGATGTTGCCAATCTGGCTAAAGTCTTTGGCCCTACAATAGTGGCCCAT
  GCTGTGCCCAATCCAGACCCAGTGACAATGTTACAGGACATCAAGCGTCAACCCAAGGTG
  GTTGAGCGCCTGCTTTCCTTGCCTCTGGAGTATTGGAGTCAGTTCATGATGGTGGAGCAA
  GAGAACATTGACCCCCTACATGTCATTGAAAACTCAAATGCCTTTTCAACACCACAGACA
  CCAGATATTAAAGTGAGTTTACTGGGACCTGTGACCACTCCTGAACATCAGCTTCTCAAG
  ACTCCTTCATCTAGTTCCCTGTCACAGAGAGTCCGTTCCACCCTCACCAAGAACACTCCT
  AGATTTGGGAGCAAAAGCAAGTCTGCCACTAACCTAGGACGACAAGGCAACTTTTTTGCT
  TCTCCAATGCTCAAGTGAAGTCACATCTGCCTGTTACTTCCCAGCATTGACTGACTATAA
  GAAAGGACACATCTGTACTCTGCTCTGCAGCCCTCCTGTACTCATTACTACTTTTAGCAT
  TCTCCAGGCTTTTACTCAAGTTTAATTGTGCATGAGGGTTTTATTAAAACTATATATATC
  TCCCCTTCCTTCTCCTCAAGTCACATAATATCAGCACTTTGTGCTGGTCATTGTTGGGAG
  CTTTTAGATGAGACATCTTTCCAGGGGTAGAAGGGTTAGTATGGAATTGGGTTGTGATTC
  TTTTTGGGGAAGGGGGTTATTGTXXXXXXXXXXXXXXXXXXCTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_013277 unedited
  TTCGGATTTGTATACGACTCATATAGGGCGGCCGCGATTCGGCACGAGGGTGGGCGCGGC
  GCTGCTCTGCCGTTGGGTGAGGCGCGGAGCGAAGTGAAGGGTGGCCCAGGTGGGGCCAGG
  CTGACTGAAAAAGATGGATACTATGATGCTGAATGTGCGGAATCTGTTTGAGCAGCTTGT
  GCGCCGGGTGGAGATTCTCAGTGAAGGAAATGAAGTCCAATTTATCCAGTTGGCGAAGGA
  CTTTGAGGATTTCCGTAAAAAGTGGCAGAGGACTGACCATGAGCTGGGGAAATACAAGGA
  TCTTTTGATGAAAGCAGAGACTGAGCGAAGTGCTCTGGATGTTAAGCTGAAGCATGCACG
  TAATCAGGTGGATGTAGAGATCAAACGGAGACAGAGAGCTGAGGCTGACTGCGAAAAGCT
  GGAACGACAGATTCAGCTGATTCGAGAGATGCTCATGTGTGACACATCTGGCAGCATTCA
  ACTAAGCGAGGAGCAAAAATCAGCTCTGGCTTTTCTCAACAGAGGCCAACCATCCAGCAG
  CAATGCTGGGAACAAAAGACTATCAACCATTGATGAATCTGGTTCCATTTTATCAGATAT
  CAGCTNTGACAAGACTGATGAATCACTGGATTGGGACTCTTCTTTGGTGAAGACTNTCAN
  ACTGAAGAAGAGAGAANAGAGGCGCTCTACTAGCCGACAGTTTGTTGATGGTCCCCCTGG
  ACCTGTAAAGAAAACTCGTTCCATTGGCTCTGCAGTAGACCCAGGGAATGAATCCATAGN
  TGCAAAAACTACAGTGACTGTTCCCAATGATGGCGGCCCCCATCGAACTGTGTCCACTAT
  TGAGACTGTGCCATATTGNACCAGNAGCCGAAGGAAACAGGTACTTTACACCTTGGAACA
  GTGACTCCACCCCTGACAGAAGCAGCTG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_013277 unedited
  TAGAGTCGAGTTTTTTTTTTTTTTTTTTATTTTGAAAAACTATTTACTTTTTTTCCAATA
  TTATCCCAAATAGGTGTTTTACAGATAAGGGTCAATACGAAGTCAAACATTCTACAGAAG
  AAAATCGTTTTTACAGACATTAAGAATAATTTTAACAGAAGAAAAAGCTCACATCTATCT
  AGATGTGGCTATGTTCCATGGGAAAAATTTCAGCATCCAAAGTGCAAAGAAAAAATGACT
  GTAGCTTTTCTTACCACAAAATATTGACAATCTTCCCTTATAGCCTACTCTTTATTGTTA
  GTTGGGATGCCAAAGGATGATATATTGACCTTTAGAAGTTGGGCTCCACTGGACAAGGTT
  GGGGGTATGGGGGCCAAGCATCAGAATGAATTCAATTTTAAAAGAAAAACTGGCTTTGAC
  CCCAAATGAACCCAAAGTTCAGCCAGCGGCACATCAGAGATAAATACGAGTTGTACTTTC
  ACATTTACAAGGTTGTGCCACTCAACACTATTAAAGACCTAATCATCCAAATCAAAGCTA
  CGCATACTCCCATCACTAGTTCTGGTCTCAATGCATCCCATTTTTATGAAAGCTCCATAT
  TATAGCTCAGTTCATAATGGGGAATGAGACCTTCTGGTTCTTTAGAGGAGGCATCCTAAA
  TCCTCTGGTCTATCCTTTCTTTGCCCTGCCCTCCCACTCCCACCCTGAGAAAGCTAATCT
  TATCAGATTAGTAGGGTTTCTGCACTGNCTCCCGAAAATCAGTCTAAATGAACCTAAAGA
  ACGATCTTCTTTGACCCGTTTTTGGCTTTAACCACAGGACCTTACCCCCTTTCCCCAAAG
  AATCCCACCAATTCCTCTTACCCCTTTACCCTTGAAAGAAGTTCATTAAAGCCCCCAAAT
  GACACCCAAATGCTGATTTTTGGGATTGGGGAAAGGAGGGGAAATTATTAGTTTAATAAC
  CCCTGCCCAATAACTGGTAAACCGCGAAAGCTCAATTTTAGGTACCGAGGCGCAACAACC
  AAGGTGCCTTTTAAACCAAGTGGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_013277
• ORF Size: 1899 bp
• Insert Size: 3570
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_013277.2, NP_037409.2
• RefSeq Size: 3237
• RefSeq ORF: 1899
• Locus ID: 29127
• Domains: RhoGAP, DAG_PE-bind
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a GTPase-activating protein (GAP) that is a compoment of the centralspindlin complex. This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho-mediated signals. This protein plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for this gene. There is a pseudogene for this gene on chromosome 12. [provided by RefSeq, Feb 2016]
  Transcript Variant: This variant (1) is the reference variant. Variants 1, 2, 3, 4, 5, 6, 7, 8, and 9 encode the same isoform (a).