GLRB (NM_000824) Human Tagged ORF Clone
CAT#: RC207619L1
- LentiORF®
Lenti ORF clone of Human glycine receptor, beta (GLRB), transcript variant 1, Myc-DDK-tagged
"NM_000824" in other vectors (6)
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | GLRB |
Synonyms | HKPX2 |
Vector | pLenti-C-Myc-DDK |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC207619).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_000824 |
ORF Size | 1491 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_000824.2 |
RefSeq Size | 3076 bp |
RefSeq ORF | 1494 bp |
Locus ID | 2743 |
UniProt ID | P48167 |
Cytogenetics | 4q32.1 |
Domains | Neur_chan_memb, Neur_chan_LBD |
Protein Families | Druggable Genome, Ion Channels: Cys-loop Receptors, Transmembrane |
Protein Pathways | Neuroactive ligand-receptor interaction |
MW | 56.1 kDa |
Gene Summary | This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC321743 | GLRB (untagged)-Human glycine receptor, beta (GLRB), transcript variant 1 |
USD 310.00 |
|
RC207619 | GLRB (Myc-DDK-tagged)-Human glycine receptor, beta (GLRB), transcript variant 1 |
USD 420.00 |
|
RG207619 | GLRB (GFP-tagged) - Human glycine receptor, beta (GLRB), transcript variant 1 |
USD 460.00 |
|
RC207619L2 | Lenti ORF clone of Human glycine receptor, beta (GLRB), transcript variant 1, mGFP tagged |
USD 620.00 |
|
RC207619L3 | Lenti ORF clone of Human glycine receptor, beta (GLRB), transcript variant 1, Myc-DDK-tagged |
USD 620.00 |
|
RC207619L4 | Lenti ORF clone of Human glycine receptor, beta (GLRB), transcript variant 1, mGFP tagged |
USD 620.00 |
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