CysLT1 (CYSLTR1) (NM_006639) Human Tagged ORF Clone
CAT#: RC207763L2
- LentiORF®
Lenti ORF clone of Human cysteinyl leukotriene receptor 1 (CYSLTR1), mGFP tagged
"NM_006639" in other vectors (6)
Product Images
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | mGFP |
Symbol | CYSLTR1 |
Synonyms | CYSLT1; CYSLT1R; CYSLTR; HMTMF81 |
Vector | pLenti-C-mGFP |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC207763).
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Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_006639 |
ORF Size | 1011 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_006639.2, NP_006630.1 |
RefSeq Size | 1537 |
RefSeq ORF | 1014 |
Locus ID | 10800 |
Domains | 7tm_1 |
Protein Families | Druggable Genome, GPCR, Transmembrane |
Protein Pathways | Calcium signaling pathway, Neuroactive ligand-receptor interaction |
MW | 38.4 kDa |
Gene Summary | This gene encodes a member of the G-protein coupled receptor 1 family. The encoded protein is a receptor for cysteinyl leukotrienes, and is involved in mediating bronchoconstriction via activation of a phosphatidylinositol-calcium second messenger system. Activation of the encoded receptor results in contraction and proliferation of bronchial smooth muscle cells, eosinophil migration, and damage to the mucus layer in the lung. Upregulation of this gene is associated with asthma and dysregulation may also be implicated in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC115965 | CYSLTR1 (untagged)-Human cysteinyl leukotriene receptor 1 (CYSLTR1) |
USD 310.00 |
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RC207763 | CYSLTR1 (Myc-DDK-tagged)-Human cysteinyl leukotriene receptor 1 (CYSLTR1) |
USD 590.00 |
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RG207763 | CYSLTR1 (GFP-tagged) - Human cysteinyl leukotriene receptor 1 (CYSLTR1) |
USD 460.00 |
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RC207763L1 | Lenti ORF clone of Human cysteinyl leukotriene receptor 1 (CYSLTR1), Myc-DDK-tagged |
USD 620.00 |
|
RC207763L3 | Lenti ORF clone of Human cysteinyl leukotriene receptor 1 (CYSLTR1), Myc-DDK-tagged |
USD 768.00 |
|
RC207763L4 | Lenti ORF clone of Human cysteinyl leukotriene receptor 1 (CYSLTR1), mGFP tagged |
USD 768.00 |
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