CysLT1 (CYSLTR1) (NM_006639) Human Untagged Clone

CAT#: SC115965

CYSLTR1 (untagged)-Human cysteinyl leukotriene receptor 1 (CYSLTR1)


  "NM_006639" in other vectors (6)

Reconstitution Protocol

USD 310.00

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol CYSLTR1
Synonyms CYSLT1; CYSLT1R; CYSLTR; HMTMF81
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC115965 sequence for NM_006639 edited (data generated by NextGen Sequencing)
ATGGATGAAACAGGAAATCTGACAGTATCTTCTGCCACATGCCATGACACTATTGATGAC
TTCCGCAATCAAGTGTATTCCACCTTGTACTCTATGATCTCTGTTGTAGGCTTCTTTGGC
AATGGCTTTGTGCTCTATGTCCTCATAAAAACCTATCACAAGAAGTCAGCCTTCCAAGTA
TACATGATTAATTTAGCAGTAGCAGATCTACTTTGTGTGTGCACACTGCCTCTCCGTGTG
GTCTATTATGTTCACAAAGGCATTTGGCTCTTTGGTGACTTCTTGTGCCGCCTCAGCACC
TATGCTTTGTATGTCAACCTCTATTGTAGCATCTTCTTTATGACAGCCATGAGCTTTTTC
CGGTGCATTGCAATTGTTTTTCCAGTCCAGAACATTAATTTGGTTACACAGAAAAAAGCC
AGGTTTGTGTGTGTAGGTATTTGGATTTTTGTGATTTTGACCAGTTCTCCATTTCTAATG
GCCAAACCACAAAAAGATGAGAAAAATAATACCAAGTGCTTTGAGCCCCCACAAGACAAT
CAAACTAAAAATCATGTTTTGGTCTTGCATTATGTGTCATTGTTTGTTGGCTTTATCATC
CCTTTTGTTATTATAATTGTCTGTTACACAATGATCATTTTGACCTTACTAAAAAAATCA
ATGAAAAAAAATCTGTCAAGTCATAAAAAGGCTATAGGAATGATCATGGTCGTGACCGCT
GCCTTTTTAGTCAGTTTCATGCCATATCATATTCAACGTACCATTCACCTTCATTTTTTA
CACAATGAAACTAAACCCTGTGATTCTGTCCTTAGAATGCAGAAGTCCGTGGTCATAACC
TTGTCTCTGGCTGCATCCAATTGTTGCTTTGACCCTCTCCTATATTTCTTTTCTGGGGGT
AACTTTAGGAAAAGGCTGTCTACATTTAGAAAGCATTCTTTGTCCAGCGTGACTTATGTA
CCCAGAAAGAAGGCCTCTTTGCCAGAAAAAGGAGAAGAAATATGTAAAGTATAG

Clone variation with respect to NM_006639.2
927 c=>t
>OriGene 5' read for NM_006639 unedited
NGGTTGAGGATTTTGTNATACGATTTACTATAGGGTCGGCCGCGAAATTCGCACGAGGTG
CTTTTACGACCCTACAGGGTATCAAGATACTGTGCAGCTCGCCAACAAGGATTAATTGCA
AGGACTGGTAGATCGAATTTACTGAAGACTTGGAGCTTGCTTCTGAGAACAAACGCAAAA
GGACAGTAAACTGTGGACCTTGAAGTTAGCAGCGTGGGCTTCCTCTAATATTACACCGTA
AAAGGCATTGATCACCATAAGAAGGAACATTTGTGAAGGTACTCCAGTGCCAGAAAGAGG
CACAAAGCAGACATATGTAGAGAAACATGGATGAAACAGGAAATCTGACAGTATCTTCTA
TCACATGCCATGACACTATTGATGACTTCCGCAATCAAGTGTATTCCACCTTGTACTCTA
TGATCTCTGTTGTAGGCTTCTTTGGCAATGGCTTTGTGCTCTATGTCCTCATAAAAACCT
ATCACAAGATAGTCAGCCTTCCAAGTATACATGATTAATTTAGCAGTAGCAGATCTACTT
TGTGTGTGCACACTGCCTCTCCGTGTGGTCTATTATGTTCACAAAGGCATTTGGCTCTTT
GGTGACTTCTTGTGCCGCCTCAGCACCTATGCTTTGTATGTCAACCTCTATTGTAGCATC
TTCTTTATGACAGCCATGAGCTCTTTCCGGTGCATTGCAATTGTTTTTCCAGTCCAGAAC
ATTAATTTGGTTACACAGAAAAAAAGCCAGGTTTGTGTGTGTAGGTATTTTGCATTTTTG
TGATTTTGACCAGTTCTTCATTTCTAATGGCCACACCACCAAAAGATGATGAAAATAATA
CCAAGTGCCTTTGAGCTCCCACAAGACATCAAACCTAAAAATCATGTTCTGGTCTCGCCA
TATGTGGCATTGTTTGGTTGCCTT
>OriGene 3' read for NM_006639 unedited
AAATAATAAANNNNNNNTTATTANNNNNGGCCACTTTTGATTACATTTTTTTTTTTGNAG
TAAGTTACTTTTTAAAAACAACTTAAAGGCACACTACACTTCAGCAAAAGCTTGTCCACG
CATATTATATTTCAGCCGTAGATGAGTTGTTGTGGCTGTTTTAAGATCAAAGCGTCCACT
GTAATATAAAAGTCACTGTAAACATATCCATGATATTCCTGTCAACATACCAATAAAAAG
TAATAAAGCAATAATAAAACTTATCGTGAACTTTCACCCATAATGCATATCATACAGCAA
AATCTCTTACATATAGTTGTATACATATACATAAATGTATGCACTTCTTAAAAGAATTTG
TAACGTGAACATTCACAATTTTCTTCATAAATCCTTTGTAGTTTATTTTGATCCCAGCAA
TTGGCATATAGAAAAGTAGATTCCTTTTCCTTTTCTCTTCTTCAGATAAGTTTTTAATTA
CTTCTATTTATATATAGGAGTGCCAGTTGTCTGGCTTCTTAAGGAAGAATTGTATGTCAT
GGATGGAGAGAAATCTCTACAGGAACCTCACTGAGCAGCTAAAACTCCACTATTCAATTT
TGGGAGCCTGAGGCAAAGGCAGAAGAAAACTGGAGACAAACTGGCTTTTGACCAGATTTC
TCCTGTTGCCATATTGAACATTGTATGGTGCTTTTAAGACCCTTTAGCTGAATACTAGTC
TGTTCTAGCACTTTTACATTCTCTTTTGGAAAGAATGGCCCTTATTTGCCTAGCGAATCA
GTACTACAAAAGAAGGTGACAGTACGTTTTATGTAACTCCTGAGTATCTTCAGTTCTCAT
CTGATGGCATGCATGCAAAGGAATATGTAGAATGATTCAGAACTATTTGGCCATTTATAT
CTAGTTTTATTTTTAATACTTTAACCTT
Restriction Sites NotI-NotI     
ACCN NM_006639
ORF Size 1014 bp
Insert Size 2550
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Reference Data
RefSeq NM_006639.2, NP_006630.1
RefSeq Size 1537
RefSeq ORF 1014
Locus ID 10800
Domains 7tm_1
Protein Families Druggable Genome, GPCR, Transmembrane
Protein Pathways Calcium signaling pathway, Neuroactive ligand-receptor interaction
Gene Summary This gene encodes a member of the G-protein coupled receptor 1 family. The encoded protein is a receptor for cysteinyl leukotrienes, and is involved in mediating bronchoconstriction via activation of a phosphatidylinositol-calcium second messenger system. Activation of the encoded receptor results in contraction and proliferation of bronchial smooth muscle cells, eosinophil migration, and damage to the mucus layer in the lung. Upregulation of this gene is associated with asthma and dysregulation may also be implicated in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1, 2, 3, and 4 encode the same protein.

Other Versions

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